Search Results - "Lemmens, Bennie B. L. G."

DNA double-strand break repair in Caenorhabditis elegans by Lemmens, Bennie B. L. G, Tijsterman, Marcel

“…Faithful repair of DNA double-strand breaks (DSBs) is vital for animal development, as inappropriate repair can cause gross chromosomal alterations that result…”
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CRISPR/Cas9-targeted mutagenesis in Caenorhabditis elegans by Waaijers, Selma, Portegijs, Vincent, Kerver, Jana, Lemmens, Bennie B L G, Tijsterman, Marcel, van den Heuvel, Sander, Boxem, Mike

“…The generation of genetic mutants in Caenorhabditis elegans has long relied on the selection of mutations in large-scale screens. Directed mutagenesis of…”
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COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining by Lemmens, Bennie B L G, Johnson, Nicholas M, Tijsterman, Marcel

“…Successful completion of meiosis requires the induction and faithful repair of DNA double-strand breaks (DSBs). DSBs can be repaired via homologous…”
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A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination by Johnson, Nicholas M, Lemmens, Bennie B L G, Tijsterman, Marcel

“…Malignant brain tumour (MBT) domain proteins are transcriptional repressors that function within Polycomb complexes. Some MBT genes are tumour suppressors, but…”
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THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1 by Kamp, Juliette A, Lemmens, Bennie B L G, Romeijn, Ron J, González-Prieto, Román, Olsen, Jesper V, Vertegaal, Alfred C O, van Schendel, Robin, Tijsterman, Marcel

“…The integrity and proper expression of genomes are safeguarded by DNA and RNA surveillance pathways. While many RNA surveillance factors have additional…”
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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε by de Souza Gama, Fernando H., Dutra, Luiz A., Hawgood, Michael, dos Reis, Caio Vinícius, Serafim, Ricardo A. M., Ferreira, Marcos A., Teodoro, Bruno V. M., Takarada, Jéssica Emi, Santiago, André S., Balourdas, Dimitrios-Ilias, Nilsson, Ann-Sofie, Urien, Bruno, Almeida, Vitor M., Gileadi, Carina, Ramos, Priscila Z., Salmazo, Anita, Vasconcelos, Stanley N. S., Cunha, Micael R., Mueller, Susanne, Knapp, Stefan, Massirer, Katlin B., Elkins, Jonathan M., Gileadi, Opher, Mascarello, Alessandra, Lemmens, Bennie B. L. G., Guimarães, Cristiano R. W., Azevedo, Hatylas, Couñago, Rafael M.

“…Vaccinia-related kinase 1 (VRK1) and the δ and ε isoforms of casein kinase 1 (CK1) are linked to various disease-relevant pathways. However, the lack of tool…”
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Erratum to: DNA double-strand break repair in Caenorhabditis elegans by Lemmens, Bennie B. L. G., Tijsterman, Marcel

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