First results of computer-enhanced optical diagnosis of bladder cancer

Bladder cancer is the sixth leading cancer cause worldwide. Non-muscle invasive tumors can be diagnosed and treated endoscopically. Based on biopsies alone, pathologists cannot determine the spatial organization of specimens, their relationship with each other, or their complete removal. To extend w...

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Bibliographic Details
Published in:Current directions in biomedical engineering Vol. 6; no. 3; pp. 246 - 249
Main Authors: Wittenberg, T., Hackner, R., Bocklitz, T., Krafft, C., Becker, W., Braun, L., Pohlmann, P., Miernik, A., Suarez-Ibarrola, R., Lemke, M. N.
Format: Journal Article
Language:English
Published: De Gruyter 01-09-2020
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Summary:Bladder cancer is the sixth leading cancer cause worldwide. Non-muscle invasive tumors can be diagnosed and treated endoscopically. Based on biopsies alone, pathologists cannot determine the spatial organization of specimens, their relationship with each other, or their complete removal. To extend white light cystoscopy as the gold standard for bladder cancer detection, diagnosis and removal of small or flat lesions, new image-based technologies have been investigated. These include a stereo-cystoscope for improved orientation and navigation, computation of 2D and 3D panoramic images for extended visualization and documentation, as well as label-free fiber-based fluorescence-lifetime imaging (FLIM) and Raman-spectroscopy in combination with statistical data analysis. Combining all these technologies, cystoscopy can will be further enhanced to include new diagnostic possibilities.
ISSN:2364-5504
2364-5504
DOI:10.1515/cdbme-2020-3062