Search Results - "Lemes, Romélia Pinheiro"

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    Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship by Pedrosa, Alano Martins, Leal, Luzia Kalyne A M, Lemes, Romélia Pinheiro G

    Published in Hematology, Transfusion and Cell Therapy (01-10-2021)
    “…INTRODUCTIONAlthough the efficacy of hydroxyurea (HU) in inhibiting erythrocyte sickling has been well demonstrated, the action of this drug on human…”
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    Journal Article
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    Sickle Cell Disease and the Kidney: Pathophysiology and Novel Biomarkers by Lemes, Romélia Pinheiro Gonçalves, Rocha Laurentino, Marilia, Castelo, Luan Rebouças, Silva Junior, Geraldo

    Published in Contributions to nephrology (01-01-2021)
    “…Clinical Background: Renal involvement in sickle cell disease (SCD), called sickle cell nephropathy (SCN), includes several renal manifestations, such as renal…”
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    Non-invasive urinary biomarkers of renal function in sickle cell disease: an overview by Laurentino, Marília Rocha, Parente Filho, Sérgio Luiz Arruda, Parente, Lívia Leal Chagas, da Silva Júnior, Geraldo Bezerra, Daher, Elizabeth De Francesco, Lemes, Romélia Pinheiro Gonçalves

    Published in Annals of hematology (01-12-2019)
    “…Sickle cell disease (SCD) is a hereditary condition characterized by homozygosis of the hemoglobin S (HbS) gene. Marked morbimortality is observed due to…”
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    Influence of βS-Globin Haplotypes and Hydroxyurea on Arginase I Levels in Sickle Cell Disease by Martins, Alice Maria Costa, Santos, T. E., Barbosa, M. C., Lemes, Romelia Pinheiro Gonçalves, Laurentino, M. R., Machado, R. P. G., Moreira, J. A., Bandeira, I. C. J.

    Published in Disease markers (01-01-2016)
    “…Introduction. Sickle cell disease (SCD) is characterized by hemoglobin S homozygosity, leading to hemolysis and vasoocclusion. The hemolysis releases arginase…”
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