Search Results - "Lemelle, Elise"

Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents by Zheng, Shilong, Zhong, Qiu, Mottamal, Madhusoodanan, Zhang, Qiang, Zhang, Changde, LeMelle, Elise, McFerrin, Harris, Wang, Guangdi

“…A series of novel pyridine-bridged analogues of combretastatin-A4 (CA-4) were designed and synthesized. As expected, the 4-atom linker configuration retained…”
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Somatic PRPF8 Mutations in Myeloid Neoplasia by Adema, Vera, Hirsch, Cassandra M., Przychodzen, Bartlomiej P., Nagata, Yasunobu, Lemelle, Elise, Nazha, Aziz, Carraway, Hetty E., Sekeres, Mikkael A., Visconte, Valeria, Maciejewski, Jaroslaw P., Padgett, Richard A

“…Somaticmutations in genes of the RNA-splicing machinery are recurrent in myeloid neoplasia. PRPF8 has a central role in the spliceosome assembly and it is…”
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High Frequency of Subclonal Myeloid Mutations Can be Found in Large Granular Lymphocyte Leukemia by LeMelle, Elise, Hirsch, Cassandra M., Clemente, Michael, Sanikommu, Srinivasa Reddy, Adema, Vera, Awada, Hassan, Przychodzen, Bartlomiej P., Carraway, Hetty E., Lichtin, Alan, Sekeres, Mikkael A., Mukherjee, Sudipto, Visconte, Valeria, Maciejewski, Jaroslaw P.

“…Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferation of cytotoxic T-lymphocytes often associated with immune cytopenias. Somatic mutations…”
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Activation of Autophagy in Models of SF3B1 Mutant MDS by Visconte, Valeria, Adema, Vera, Przychodzen, Bartlomiej P., Noe, Allison, Toth, Rachel, Hirbawi, Yasmine, Hirsch, Cassandra M., Khouri, Jack, LeMelle, Elise, Balasubramanian, Suresh K., Carraway, Hetty E., Lindner, Daniel, Advani, Anjali S., Rogers, Heesun J., Phillips, James G, Radivoyevitch, Tomas, Kelly, Kevin R, Nawrocki, Steffan T., Sekeres, Mikkael A., Maciejewski, Jaroslaw P., Carew, Jennifer

“…Background:SF3B1 is a key pre-mRNA splicing factor that is abundantly expressed in normal erythroid cells and whose mutation has been linked with high…”
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Distinct Clinical Phenotypes of Patients with Myeloid Neoplasms Carrying SF3B1 Hotspot Mutations by Khouri, Jack, Adema, Vera, Ni, Ying, Rogers, Heesun J., Przychodzen, Bartlomiej P., Hirsch, Cassandra M., Lemelle, Elise, Kuzmanovic, Teodora, Advani, Anjali S., Gerds, Aaron T., Mukherjee, Sudipto, Nazha, Aziz, Saunthararajah, Yogenthiran, Madanat, Yazan F., Patel, Bhumika J., Sole, Francesc, Nawrocki, Steffan T., Carew, Jennifer, Kalaycio, Matt, Sekeres, Mikkael A., Maciejewski, Jaroslaw P., Visconte, Valeria, Carraway, Hetty E.

“…Background: Mutations in the pre-mRNA splicing factor SF3B1 are now established as one of the classification criteria in myelodysplastic syndromes (MDS) and…”
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