Search Results - "Leme, Adriana F Paes"

A targeted proteomic strategy for the measurement of oral cancer candidate biomarkers in human saliva by Kawahara, Rebeca, Bollinger, James G., Rivera, César, Ribeiro, Ana Carolina P., Brandão, Thaís Bianca, Leme, Adriana F. Paes, MacCoss, Michael J.

“…Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most common malignancy in the world and are characterized by poor prognosis…”
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Salivary annexin A1: A candidate biomarker for periodontitis by Casarin, Renato C. V., Salmon, Cristiane R., Stolf, Camila S., Paz, Hélvis E. S., Rangel, Thiago P., Domingues, Romênia R., Pauletti, Bianca A., Paes‐Leme, Adriana F., Araújo, Cassia, Santamaria, Mauro P., Ruiz, Karina S., Monteiro, Mabelle F.

“…Aim To compare the salivary proteomic profile of periodontitis‐affected (PA) parents and their offspring to periodontally healthy (PH) dyads in the pursuit of…”
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Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses by Ribeiro-Filho, Helder V., Coimbra, Lais D., Cassago, Alexandre, Rocha, Rebeca P. F., Guerra, João Victor da Silva, de Felicio, Rafael, Carnieli, Carolina Moretto, Leme, Luiza, Padilha, Antonio Cláudio, Paes Leme, Adriana F., Trivella, Daniela B. B., Portugal, Rodrigo Villares, Lopes-de-Oliveira, Paulo Sérgio, Marques, Rafael Elias

“…Mayaro virus (MAYV) is an emerging arbovirus of the Americas that may cause a debilitating arthritogenic disease. The biology of MAYV is not fully understood…”
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Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma by Hansen, Hinrich P, Paes Leme, Adriana F, Hallek, Michael

“…Cancer cells generally recruit and influence non-malignant immune cells to support the tumor growth. Classical Hodgkin lymphoma (cHL) is a good example because…”
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Extracellular Vesicles from Different Sources of Mesenchymal Stromal Cells Have Distinct Effects on Lung and Distal Organs in Experimental Sepsis by Blanco, Natália G, Machado, Natália M, Castro, Ligia L, Antunes, Mariana A, Takiya, Christina M, Trugilho, Monique R O, Silva, Luana R, Paes Leme, Adriana F, Domingues, Romênia R, Pauletti, Bianca A, Miranda, Beatriz T, Silva, Johnatas D, Dos Santos, Claudia C, Silva, Pedro L, Rocco, Patricia R M, Cruz, Fernanda F

“…The effects of the administration of mesenchymal stromal cells (MSC) may vary according to the source. We hypothesized that MSC-derived extracellular vesicles…”
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Novel processed form of syndecan-1 shed from SCC-9 cells plays a role in cell migration by Aragão, Annelize Z B, Belloni, Marília, Simabuco, Fernando M, Zanetti, Mariana R, Yokoo, Sami, Domingues, Romênia R, Kawahara, Rebeca, Pauletti, Bianca A, Gonçalves, Anderson, Agostini, Michelle, Graner, Edgard, Coletta, Ricardo D, Fox, Jay W, Paes Leme, Adriana F

“…The extracellular milieu is comprised in part by products of cellular secretion and cell surface shedding. The presence of such molecules of the sheddome and…”
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Bothrops jararaca venom proteome rearrangement upon neonate to adult transition by Zelanis, André, Tashima, Alexandre K., Pinto, Antônio F. M., Paes Leme, Adriana F., Stuginski, Daniel R., Furtado, Maria F., Sherman, Nicholas E., Ho, Paulo L., Fox, Jay W., Serrano, Solange M. T.

“…The pharmacological activities displayed by Bothrops jararaca venom undergo a significant ontogenetic shift. Similarly, the diet of this species changes from…”
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Sirtuin E deacetylase is required for full virulence of Aspergillus fumigatus by Wassano, Natália S., da Silva, Gabriela B., Reis, Artur H., A. Gerhardt, Jaqueline, Antoniel, Everton P., Akiyama, Daniel, Rezende, Caroline P., Neves, Leandro X., Vasconcelos, Elton J. R., de Figueiredo, Fernanda L., Almeida, Fausto, de Castro, Patrícia A., Pinzan, Camila F., Goldman, Gustavo H., Paes Leme, Adriana F., Fill, Taicia P., Moretti, Nilmar S., Damasio, André

“…Aspergillus fumigatus represents a public health problem due to the high mortality rate in immunosuppressed patients and the emergence of antifungal-resistant…”
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CD30-Positive Extracellular Vesicles Enable the Targeting of CD30-Negative DLBCL Cells by the CD30 Antibody-Drug Conjugate Brentuximab Vedotin by Lobastova, Liudmila, Lettau, Marcus, Babatz, Felix, de Oliveira, Thais Dolzany, Nguyen, Phuong-Hien, Pauletti, Bianca Alves, Schauss, Astrid C., Dürkop, Horst, Janssen, Ottmar, Paes Leme, Adriana F., Hallek, Michael, Hansen, Hinrich P.

“…CD30, a member of the TNF receptor superfamily, is selectively expressed on a subset of activated lymphocytes and on malignant cells of certain lymphomas, such…”
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Secretome Profiling of Periodontal Ligament from Deciduous and Permanent Teeth Reveals a Distinct Expression Pattern of Laminin Chains by Giovani, Priscila A, Salmon, Cristiane R, Martins, Luciane, Paes Leme, Adriana F, Rebouças, Pedro, Puppin Rontani, Regina M, Mofatto, Luciana S, Sallum, Enilson A, Nociti, Jr, Francisco H, Kantovitz, Kamila R

“…It has been suggested that there are histological and functional distinctions between the periodontal ligament (PDL) of deciduous (DecPDL) and permanent…”
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ZIF‑8 Metal–Organic Framework Electrochemical Biosensor for the Detection of Protein–Protein Interaction by Trino, Luciana D, Albano, Luiz G. S, Granato, Daniela C, Santana, Aline G, de Camargo, Davi H. S, Correa, Catia C, Bof Bufon, Carlos C, Paes Leme, Adriana F

“…In this study, a novel label-free electrochemical biosensor based on the zeolitic imidazole framework (ZIF-8) was developed for monitoring protein–protein…”
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Some aspects of the venom proteome of the Colubridae snake Philodryas olfersii revealed from a Duvernoy’s (venom) gland transcriptome by Ching, Ana T.C., Rocha, Marisa M.T., Paes Leme, Adriana F., Pimenta, Daniel C., de Fátima D. Furtado, Maria, Serrano, Solange M.T., Ho, Paulo L., Junqueira-de-Azevedo, Inácio L.M.

“…We investigated the putative toxins of Philodryas olfersii (Colubridae), a representative of a family of snakes neglected in venom studies despite their…”
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Integrated proteomics identified up-regulated focal adhesion-mediated proteins in human squamous cell carcinoma in an orthotopic murine model by Granato, Daniela C, Zanetti, Mariana R, Kawahara, Rebeca, Yokoo, Sami, Domingues, Romênia R, Aragão, Annelize Z, Agostini, Michelle, Carazzolle, Marcelo F, Vidal, Ramon O, Flores, Isadora L, Korvala, Johanna, Cervigne, Nilva K, Silva, Alan R S, Coletta, Ricardo D, Graner, Edgard, Sherman, Nicholas E, Paes Leme, Adriana F

“…Understanding the molecular mechanisms of oral carcinogenesis will yield important advances in diagnostics, prognostics, effective treatment, and outcome of…”
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Extracellular vesicles in carcinoma microenvironment by Carvalho-Silva, Larissa Tinô de, Normando, Ana Gabriela C, Sá, Jamile de Oliveira, Dos Santos, Erison Santana, De Rossi, Tatiane, Busso-Lopes, Ariane Fidelis, de Oliveira, Ana Karina, Paes Leme, Adriana F

“…Cancer is a significant cause of death, precluding increasing life expectancy worldwide. That is a multifactorial disease initiated by intrinsic or extrinsic…”
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HIV-1 Nef Changes the Proteome of T Cells Extracellular Vesicles Depleting IFITMs and Other Antiviral Factors by da Silva-Januário, Mara E, da Costa, Cristina S, Tavares, Lucas A, Oliveira, Ana K, Januário, Yunan C, de Carvalho, Andreia N, Cassiano, Murilo H A, Rodrigues, Roger L, Miller, Michael E, Palameta, Soledad, Arns, Clarice W, Arruda, Eurico, Paes Leme, Adriana F, daSilva, Luis L P

“…Extracellular vesicles (EVs) are biomolecule carriers for intercellular communication in health and disease. Nef is a HIV virulence factor that is released…”
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Functional annotation and biological interpretation of proteomics data by Carnielli, Carolina M., Winck, Flavia V., Paes Leme, Adriana F.

“…Proteomics experiments often generate a vast amount of data. However, the simple identification and quantification of proteins from a cell proteome or…”
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Analysis of the subproteomes of proteinases and heparin-binding toxins of eight Bothrops venoms by Leme, Adriana F. Paes, Kitano, Eduardo S, Furtado, Maria F, Valente, Richard H, Camargo, Antonio C.M, Ho, Paulo L, Fox, Jay W, Serrano, Solange M.T

“…Viperid snakes show the most complex snake-venom proteomes and offer an intriguing challenge in terms of understanding the nature of their components and the…”
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Activation of leukocyte rolling by the cysteine-rich domain and the hyper-variable region of HF3, a snake venom hemorrhagic metalloproteinase by Menezes, Milene C., Paes Leme, Adriana F., Melo, Robson L., Silva, Carlos A., Della Casa, Maisa, Bruni, Fernanda M., Lima, Carla, Lopes-Ferreira, Mônica, Camargo, Antonio C.M., Fox, Jay W., Serrano, Solange M.T.

“…The functionality of the disintegrin-like/cysteine-rich domains of snake venom metalloproteinases (SVMPs) has been shown to reside in the cysteine-rich region,…”
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Proteomics of serum-derived extracellular vesicles are associated with the severity and different clinical profiles of patients with COVID-19: An exploratory secondary analysis by Paes Leme, Adriana F., Yokoo, Sami, Normando, Ana Gabriela C., Ormonde, João Vitor S., Domingues, Romenia Ramos, Cruz, Fernanda F., Silva, Pedro L., Souza, Bruno S.F., dos Santos, Claudia C., Castro-Faria-Neto, Hugo, Martins, Camila Marinelli, Lopes-Pacheco, Miquéias, Rocco, Patricia R.M.

“…Coronavirus disease 2019 (COVID-19) is characterized by a broad spectrum of clinical manifestations with the potential to progress to multiple organ…”
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CD30 on extracellular vesicles from malignant Hodgkin cells supports damaging of CD30 ligand-expressing bystander cells with Brentuximab-Vedotin, in vitro by Hansen, Hinrich P, Trad, Ahmad, Dams, Maria, Zigrino, Paola, Moss, Marcia, Tator, Maximilian, Schön, Gisela, Grenzi, Patricia C, Bachurski, Daniel, Aquino, Bruno, Dürkop, Horst, Reiners, Katrin S, von Bergwelt-Baildon, Michael, Hallek, Michael, Grötzinger, Joachim, Engert, Andreas, Paes Leme, Adriana F, Pogge von Strandmann, Elke

“…The goal of targeted immunotherapy in cancer is to damage both malignant and tumor-supporting cells of the microenvironment but spare unaffected tissue. The…”
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