Search Results - "Leme, A. F. Paes"

The Role of Sucrose in Cariogenic Dental Biofilm Formation—New Insight by Leme, A.F. Paes, Koo, H., Bellato, C.M., Bedi, G., Cury, J.A.

“…Dental caries is a biofilm-dependent oral disease, and fermentable dietary carbohydrates are the key environmental factors involved in its initiation and…”
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Extracellular vesicles from oral squamous carcinoma cells display pro‐ and anti‐angiogenic properties by Andrade, ALDL, Oliveira, CE, Dourado, MR, Macedo, CCS, Winck, FV, Paes Leme, AF, Salo, T, Coletta, RD, Almeida Freitas, R, Galvão, HC

“…Background A new intercellular communication mode established by neoplastic cells and tumor microenvironment components is based on extracellular vesicles…”
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The characterization of a thermostable and cambialistic superoxide dismutase from Thermus filiformis by Mandelli, F., Franco Cairo, J.P.L., Citadini, A.P.S., Büchli, F., Alvarez, T.M., Oliveira, R.J., Leite, V.B.P., Paes Leme, A.F., Mercadante, A.Z., Squina, F.M.

“…The superoxide dismutase (TfSOD) gene from the extremely thermophilic bacterium Thermus filiformis was cloned and expressed at high levels in mesophilic host…”
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Proteomic analysis of matrix of dental biofilm formed under dietary carbohydrate exposure by Moi, G P, Cury, J A, Dombroski, T C D, Pauletti, B A, Paes Leme, A F

“…To evaluate whether protein changes in extracellular matrix of dental biofilm are a unique property of sucrose, this in situ study was conducted using as…”
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Effects of sucrose on the extracellular matrix of plaque-like biofilm formed in vivo, studied by proteomic analysis by Paes Leme, A F, Bellato, C M, Bedi, G, Cury, A A Del Bel, Koo, H, Cury, J A

“…Previous studies have shown that sucrose promotes changes in the composition of the extracellular matrix (ECM) of plaque-like biofilm (PLB), but its effect on…”
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Functional characterization and synergic action of fungal xylanase and arabinofuranosidase for production of xylooligosaccharides by Gonçalves, T.A., Damásio, A.R.L., Segato, F., Alvarez, T.M., Bragatto, J., Brenelli, L.B., Citadini, A.P.S., Murakami, M.T., Ruller, R., Paes Leme, A.F., Prade, R.A., Squina, F.M.

“…▸ Hypersecretion of xylanase and arabinofuranosidase by fungal expression system. ▸ Biochemical and biophysical characterization of both enzymes. ▸ Depiction…”
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Thermal adaptation strategies of the extremophile bacterium Thermus filiformis based on multi-omics analysis by Mandelli, F., Couger, M. B., Paixão, D. A. A., Machado, C. B., Carnielli, C. M., Aricetti, J. A., Polikarpov, I., Prade, R., Caldana, C., Paes Leme, A. F., Mercadante, A. Z., Riaño-Pachón, D. M., Squina, Fabio Marcio

“…Thermus filiformis is an aerobic thermophilic bacterium isolated from a hot spring in New Zealand. The experimental study of the mechanisms of thermal…”
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Temporal relationship between sucrose-associated changes in dental biofilm composition and enamel demineralization by Vale, G C, Tabchoury, C P M, Arthur, R A, Del Bel Cury, A A, Paes Leme, A F, Cury, J A

“…The aim of this study was to investigate the temporal relationship between changes in biofilm composition and enamel demineralization following exposure to…”
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Bothrops protease A, a unique highly glycosylated serine proteinase, is a potent, specific fibrinogenolytic agent by PAES LEME, A. F., PREZOTO, B. C., YAMASHIRO, E. T., BERTHOLIM, L., TASHIMA, A. K., KLITZKE, C. F., CAMARGO, A. C. M., SERRANO, S. M. T.

“…Background: The hemostatic system is the major target of snake venom serine proteinases (SVSPs) that act on substrates of the coagulation, fibrinolytic and…”
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Rutile nano-bio-interactions mediate dissimilar intracellular destiny in human skin cells by Sanches, P. L, Souza, W, Gemini-Piperni, S, Rossi, A. L, Scapin, S, Midlej, V, Sade, Y, Leme, A. F. Paes, Benchimol, M, Rocha, L. A, Carias, R. B. V, Borojevic, R, Granjeiro, J. M, Ribeiro, A. R

“…The use of nanoparticles (NPs) in the healthcare market is growing exponentially, due to their unique physicochemical properties. Titanium dioxide…”
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Human FEZ1 Protein Forms a Disulfide Bond Mediated Dimer: Implications for Cargo Transport by Alborghetti, M. R, Furlan, A. S, Silva, J. C, Paes Leme, A. F, Torriani, I. C. L, Kobarg, J

“…The human proteins FEZ1 (fasciculation and elongation protein zeta 1) and FEZ2 are orthologs of the protein UNC-76 from C. elegans, involved in the growth and…”
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In situ Effect of Frequent Sucrose Exposure on Enamel Demineralization and on Plaque Composition after APF Application and F Dentifrice Use by Paes Leme, A.F., Dalcico, R., Tabchoury, C.P.M., Del Bel Cury, A.A., Rosalen, P.L., Cury, J.A.

“…Since the effect of the combination of methods of fluoride use on enamel demineralization and on plaque composition is not clearly established, this study…”
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Salivary pellicle composition and multispecies biofilm developed on titanium nitrided by cold plasma by Cavalcanti, I.M.G, Ricomini Filho, A.P, Lucena-Ferreira, S.C, da Silva, W.J, Paes Leme, A.F, Senna, P.M, Del Bel Cury, A.A

“…Abstract Objective The aim of this study was to evaluate the composition of the salivary pellicle (SP) and multispecies biofilm developed on titanium nitrided…”
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Acidulated phosphate fluoride application changes the protein composition of human acquired enamel pellicle by Masson, N, Domingues, R R, Cury, J A, Paes Leme, A F

“…We evaluated, by proteomic analysis, whether the chemical changes provoked on enamel by acidulated phosphate fluoride (APF) application alter the protein…”
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Caries progression and inhibition in human and bovine root dentine in situ by Hara, A T, Queiroz, C S, Paes Leme, A F, Serra, M C, Cury, J A

“…Since the use of bovine instead of human dentine to evaluate cariogenic and anticariogenic substances is not well established, this in situ study was…”
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Trypanosoma cruzi mitochondrial tryparedoxin peroxidase is located throughout the cell and its pull down provides one step towards the understanding of its mechanism of action by Peloso, E.F., Dias, L., Queiroz, R.M.L., Leme, A.F.P. Paes, Pereira, C.N., Carnielli, C.M., Werneck, C.C., Sousa, M.V., Ricart, C.A.O., Gadelha, F.R.

“…Trypanosoma cruzi depends on the effectiveness of redox metabolism to survive and ensure infection in the host. Homeostasis of redox metabolism in T. cruzi is…”
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Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ by Pecharki, G D, Cury, J A, Paes Leme, A F, Tabchoury, C P M, Del Bel Cury, A A, Rosalen, P L, Bowen, W H

“…Since the effect of iron (Fe) on the cariogenicity of sucrose in humans is unexplored, this study assessed in situ the effect of Fe co-crystallized with…”
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Effect of luting cement on dental biofilm composition and secondary caries around metallic restorations in situ by Moura, J S, Lima, E M C X, Paes Leme, A F, Del Bel Cury, Altair A, Tabchoury, C P M, Cury, J A

“…Since the importance of luting cement on secondary caries in enamel and dentin is unknown, an in situ crossover study was conducted in three phases over 21…”
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New insights into the structural elements involved in the skin haemorrhage induced by snake venom metalloproteinases by Oliveira, Ana K, Paes Leme, Adriana F, Asega, Amanda F, Camargo, Antonio C M, Fox, Jay W, Serrano, Solange M T

“…Haemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon resulting in capillary disruption and extravasation. This study analysed…”
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SALIVARY PROTEINS AS MARKERS OF RADIATION-RELATED ORAL TOXICITIES by Santos-Silva, AR, Palmier, NR, Migliorati, CA, Prado-Ribeiro, AC, de Rossi, T, Lopes, AF Busso, Leme, AF Paes, de Castro, G, Lopes, MA, Brandão, TB

“…Lately, there has been a great search for molecular-based treatments. The aim of this study was to characterize the salivary proteomic profile of patients…”
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