Search Results - "Lemcke, René"
-
1
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2022)“…Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of Hcrt causes the sleep disorder…”
Get full text
Journal Article -
2
Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Published in eLife (12-09-2023)“…Infection with Influenza A virus (IAV) causes the well-known symptoms of the flu, including fever, loss of appetite, and excessive sleepiness. These responses,…”
Get full text
Journal Article -
3
Deciphering Molecular Host-Pathogen Interactions During Ramularia Collo-Cygni Infection on Barley
Published in Frontiers in plant science (22-10-2021)“…Ramularia collo-cygni is the causal agent of Ramularia leaf spot disease (RLS) on barley and became, during the recent decades, an increasing threat for…”
Get full text
Journal Article -
4
A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis
Published in Nature communications (01-09-2022)“…The ginkgo tree ( Ginkgo biloba ) is considered a living fossil due to its 200 million year’s history under morphological stasis. Its resilience is partly…”
Get full text
Journal Article -
5
Integrative transcript to proteome analysis of barley during Ramularia collo-cygni leaf spot development identified several proteins that are related to fungal recognition and infection responses
Published in Frontiers in plant science (28-03-2024)“…leaf spot (RLS) disease is a growing threat to barley cultivation, but with no substantial resistance identified to date. Similarly, the understanding of the…”
Get full text
Journal Article -
6
Non-invasive detection of narcolepsy type I phenotypical features and disease progression by continuous home-cage monitoring of activity in two mouse models: the HCRT-KO and DTA model
Published in Sleep (New York, N.Y.) (01-09-2023)“…Abstract Narcolepsy type 1 (NT1) is a neurological disorder caused by disruption of hypocretin (HCRT; or orexin) neurotransmission leading to fragmented…”
Get full text
Journal Article -
7
Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Published in eLife (12-09-2023)“…Infection with Influenza A virus (IAV) causes the well-known symptoms of the flu, including fever, loss of appetite, and excessive sleepiness. These responses,…”
Get full text
Journal Article -
8
Dissection of Ramularia Leaf Spot Disease by Integrated Analysis of Barley and Ramularia collo-cygni Transcriptome Responses
Published in Molecular plant-microbe interactions (01-02-2019)“…Ramularia leaf spot disease (RLS), caused by the ascomycete fungus Ramularia collo-cygni, has emerged as a major economic disease of barley. No substantial…”
Get full text
Journal Article