Search Results - "Lellis, Laura De"
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Low AMY1 Gene Copy Number Is Associated with Increased Body Mass Index in Prepubertal Boys
Published in PloS one (05-05-2016)“…Genome-wide association studies have identified more than 60 single nucleotide polymorphisms associated with Body Mass Index (BMI). Additional genetic…”
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2
Tgf-β1 transcriptionally promotes 90K expression: possible implications for cancer progression
Published in Cell death discovery (22-04-2021)“…The 90K protein, also known as Mac-2 BP or LGALS3BP, can activate the immune response in part by increasing major histocompatibility (MHC) class I levels. In…”
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3
Bridelia speciosa Müll.Arg. Stem bark Extracts as a Potential Biomedicine: From Tropical Western Africa to the Pharmacy Shelf
Published in Antioxidants (02-02-2020)“…species have been used in traditional African medicine for the management of diverse human ailments. In the current work, the detailed phytochemical profiles…”
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Correction: Tgf-β1 transcriptionally promotes 90K expression: possible implications for cancer progression
Published in Cell death discovery (11-05-2021)Get full text
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Resveratrol Derivative Exhibits Marked Antiproliferative Actions, Affecting Stemness in Pancreatic Cancer Cells
Published in International journal of molecular sciences (19-01-2023)“…Pancreatic cancer (PC) is one of the deadliest malignancies, with an increasing incidence and limited response to current therapeutic options. Therefore, more…”
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The Anticancer Potential of Peroxisome Proliferator‐Activated Receptor Antagonists
Published in ChemMedChem (06-02-2018)“…The effects on cancer‐cell proliferation and differentiation mediated by peroxisome proliferator‐activated receptors (PPARs) have been widely studied, and…”
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Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells
Published in Scientific reports (11-09-2018)“…Paragangliomas (PGLs) are infiltrating autonomic nervous system tumors that cause important morbidity. At present, surgery is the only effective therapeutic…”
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Effects of repurposed drug candidates nitroxoline and nelfinavir as single agents or in combination with erlotinib in pancreatic cancer cells
Published in Journal of experimental & clinical cancer research (21-09-2018)“…Pancreatic cancer (PC) is the fourth most common cause of cancer death. Combination therapies with classical chemotherapeutic agents improved treatment of…”
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The Role of Dysfunctional Adipose Tissue in Pancreatic Cancer: A Molecular Perspective
Published in Cancers (09-07-2020)“…Pancreatic cancer (PC) is a lethal malignancy with rising incidence and limited therapeutic options. Obesity is a well-established risk factor for PC…”
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10
Screening of Benzimidazole-Based Anthelmintics and Their Enantiomers as Repurposed Drug Candidates in Cancer Therapy
Published in Pharmaceuticals (Basel, Switzerland) (17-04-2021)“…Repurposing of approved non-antitumor drugs represents a promising and affordable strategy that may help to increase the repertoire of effective anticancer…”
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Integrative proteomic and functional analyses provide novel insights into the action of the repurposed drug candidate nitroxoline in AsPC-1 cells
Published in Scientific reports (13-02-2020)“…We recently identified nitroxoline as a repurposed drug candidate in pancreatic cancer (PC) showing a dose-dependent antiproliferative activity in different PC…”
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Effects of PPARα inhibition in head and neck paraganglioma cells
Published in PloS one (08-06-2017)“…Head and neck paragangliomas (HNPGLs) are rare tumors that may cause important morbidity, because of their tendency to infiltrate the skull base. At present,…”
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13
Flow Cytometry Detection of Anthracycline-Treated Breast Cancer Cells: An Optimized Protocol
Published in Current issues in molecular biology (28-12-2022)“…The use of anthracycline derivatives was approved for the treatment of a broad spectrum of human tumors (i.e., breast cancer). The need to test these drugs on…”
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High Blood Concentration of Leukocyte-Derived Extracellular Vesicles Is Predictive of Favorable Clinical Outcomes in Patients with Pancreatic Cancer: Results from a Multicenter Prospective Study
Published in Cancers (29-09-2022)“…Pancreatic cancer (PC) is one of the leading causes of cancer-related death worldwide. Identification of novel tumor biomarkers is highly advocated in PC to…”
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Benzothiazole Derivatives Endowed with Antiproliferative Activity in Paraganglioma and Pancreatic Cancer Cells: Structure–Activity Relationship Studies and Target Prediction Analysis
Published in Pharmaceuticals (Basel, Switzerland) (28-07-2022)“…The antiproliferative effects played by benzothiazoles in different cancers have aroused the interest for these molecules as promising antitumor agents. In…”
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Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2020)“…Pancreatic cancer (PC) is one of the deadliest carcinomas and in most cases, which are diagnosed with locally advanced or metastatic disease, current…”
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Exosomes as Pleiotropic Players in Pancreatic Cancer
Published in Biomedicines (09-03-2021)“…Pancreatic cancer (PC) incidence is rising and due to late diagnosis, combined with unsatisfactory response to current therapeutic approaches, this tumor has…”
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Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms
Published in PloS one (20-11-2013)“…The identification of germline variants predisposing to hereditary nonpolyposis colorectal cancer (HNPCC) is crucial for clinical management of carriers, but…”
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Multicenter Comparison of PCR Assays for Detection of Human Herpesvirus 8 DNA in Semen
Published in Journal of Clinical Microbiology (01-05-1999)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Drug Repurposing, an Attractive Strategy in Pancreatic Cancer Treatment: Preclinical and Clinical Updates
Published in Cancers (05-08-2021)“…Pancreatic cancer (PC) is one of the deadliest malignancies worldwide, since patients rarely display symptoms until an advanced and unresectable stage of the…”
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