Search Results - "Lelimousin, Mickael"

Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93 by Goedhart, Joachim, von Stetten, David, Noirclerc-Savoye, Marjolaine, Lelimousin, Mickaël, Joosen, Linda, Hink, Mark A., van Weeren, Laura, Gadella, Theodorus W.J., Royant, Antoine

“…Cyan variants of green fluorescent protein are widely used as donors in Förster resonance energy transfer experiments. The popular, but modestly bright,…”
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The Hidden Conformation of Lewis x, a Human Histo-Blood Group Antigen, Is a Determinant for Recognition by Pathogen Lectins by Topin, Jérémie, Lelimousin, Mickaël, Arnaud, Julie, Audfray, Aymeric, Pérez, Serge, Varrot, Annabelle, Imberty, Anne

“…Histo-blood group epitopes are fucosylated branched oligosaccharides with well-defined conformations in solution that are recognized by receptors, such as…”
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Intrinsic Dynamics in ECFP and Cerulean Control Fluorescence Quantum Yield by Lelimousin, Mickaël, Noirclerc-Savoye, Marjolaine, Lazareno-Saez, Christelle, Paetzold, Bernhard, Le Vot, Sophie, Chazal, Richard, Macheboeuf, Pauline, Field, Martin J, Bourgeois, Dominique, Royant, Antoine

“…Enhanced cyan fluorescent protein (ECFP) and its variant Cerulean are genetically encoded fluorophores widely used as donors in FRET-based cell imaging…”
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Conformational Changes in the Epidermal Growth Factor Receptor: Role of the Transmembrane Domain Investigated by Coarse-Grained MetaDynamics Free Energy Calculations by Lelimousin, Mickaël, Limongelli, Vittorio, Sansom, Mark S. P

“…The epidermal growth factor receptor (EGFR) is a dimeric membrane protein that regulates key aspects of cellular function. Activation of the EGFR is linked to…”
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Gating-like Motions and Wall Porosity in a DNA Nanopore Scaffold Revealed by Molecular Simulations by Maingi, Vishal, Lelimousin, Mickaël, Howorka, Stefan, Sansom, Mark S. P

“…Recently developed synthetic membrane pores composed of folded DNA enrich the current range of natural and engineered protein pores and of nonbiogenic…”
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Membrane Perturbation by Carbon Nanotube Insertion: Pathways to Internalization by Lelimousin, Mickaël, Sansom, Mark S. P.

“…Carbon nanotubes (CNTs) can penetrate the membranes of cells, offering prospects for nanomedicine but problems for nanotoxicity. Molecular simulations are used…”
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Structural Basis of X-ray-Induced Transient Photobleaching in a Photoactivatable Green Fluorescent Protein by Adam, Virgile, Carpentier, Philippe, Violot, Sebastien, Lelimousin, Mickaël, Darnault, Claudine, Nienhaus, G. Ulrich, Bourgeois, Dominique

“…We have observed the photoactivatable fluorescent protein IrisFP in a transient dark state with near-atomic resolution. This dark state is assigned to a…”
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Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study by Lepsik, Martin, Sommer, Roman, Kuhaudomlarp, Sakonwan, Lelimousin, Mickaël, Paci, Emanuele, Varrot, Annabelle, Titz, Alexander, Imberty, Anne

“…Pathogenic micro-organisms utilize protein receptors (lectins) in adhesion to host tissues, a process that in some cases relies on the interaction between…”
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Effect of Noncanonical Amino Acids on Protein–Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs by Tobola, Felix, Lelimousin, Mickael, Varrot, Annabelle, Gillon, Emilie, Darnhofer, Barbara, Blixt, Ola, Birner-Gruenberger, Ruth, Imberty, Anne, Wiltschi, Birgit

“…Protein–carbohydrate interactions play crucial roles in biology. Understanding and modifying these interactions is of major interest for fighting many…”
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Interfacial activation of M37 lipase: A multi-scale simulation study by Willems, Nathalie, Lelimousin, Mickaël, Koldsø, Heidi, Sansom, Mark S.P.

“…Lipases are enzymes of biotechnological importance that function at the interface formed between hydrophobic and aqueous environments. Hydrophobic interfaces…”
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The effect of mutations in the lid region of Thermomyces lanuginosus lipase on interactions with triglyceride surfaces: A multi-scale simulation study by Willems, Nathalie, Lelimousin, Mickäel, Skjold-Jørgensen, Jakob, Svendsen, Allan, Sansom, Mark S.P.

“…•Lipases function at the interface between an amphiphilic molecular substrate surface and water.•Molecular simulations reveal interactions of Thermomyces…”
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Structural characterization of IrisFP, an optical highlighter undergoing multiple photo-induced transformations by Adam, Virgile, Lelimousin, Mickaël, Boehme, Susan, Desfonds, Guillaume, Nienhaus, Karin, Field, Martin J, Wiedenmann, Joerg, McSweeney, Sean, Nienhaus, G. Ulrich, Bourgeois, Dominique

“…Photoactivatable fluorescent proteins (FPs) are powerful fluorescent highlighters in live cell imaging and offer perspectives for optical nanoscopy and the…”
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Photoconversion of the Fluorescent Protein EosFP: A Hybrid Potential Simulation Study Reveals Intersystem Crossings by Lelimousin, Mickaël, Adam, Virgile, Nienhaus, G. Ulrich, Bourgeois, Dominique, Field, Martin J

“…Fluorescent proteins undergoing green to red photoconversion have proved to be essential tools in cell biology, notably in superlocalization nanoscopy…”
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Rational Design of Photoconvertible and Biphotochromic Fluorescent Proteins for Advanced Microscopy Applications by Adam, Virgile, Moeyaert, Benjamien, David, Charlotte C., Mizuno, Hideaki, Lelimousin, Mickaël, Dedecker, Peter, Ando, Ryoko, Miyawaki, Atsushi, Michiels, Jan, Engelborghs, Yves, Hofkens, Johan

“…Advanced fluorescence imaging, including subdiffraction microscopy, relies on fluorophores with controllable emission properties. Chief among these…”
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When Additive Molecular Dynamics Fails: Quantum Effects in Calcium-Dependent Lectin/Carbohydrate Complex by Lepsik, Martin, Lelimousin, Mickael G., Paci, Emanuele, Imberty, Anne

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Biomimetic Phospholipid Membrane Organization on Graphene and Graphene Oxide Surfaces: A Molecular Dynamics Simulation Study by Willems, Nathalie, Urtizberea, Ainhoa, Verre, Andrea F, Iliut, Maria, Lelimousin, Mickael, Hirtz, Michael, Vijayaraghavan, Aravind, Sansom, Mark S. P

“…Supported phospholipid membrane patches stabilized on graphene surfaces have shown potential in sensor device functionalization, including biosensors and…”
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Lipase Dynamics and Activation: The Case of M37 by Willems, Nathalie, Lelimousin, Mickael, Sansom, Mark S.P.

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Structure of Arabidopsis thaliana FUT1 Reveals a Variant of the GT-B Class Fold and Provides Insight into Xyloglucan Fucosylation by Rocha, Joana, Cicéron, Félix, de Sanctis, Daniele, Lelimousin, Mickael, Chazalet, Valérie, Lerouxel, Olivier, Breton, Christelle

“…The plant cell wall is a complex and dynamic network made mostly of cellulose, hemicelluloses, and pectins. Xyloglucan, the major hemicellulosic component in…”
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Transmembrane Helix Association of ErbB Receptors Investigated by Coarse-Grained Metadynamics Simulations by Lelimousin, Mickael, Limongelli, Vittorio, Sansom, Mark S.P.

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Highly Enhanced Conformational Sampling of the Transmembrane Domain of Egf Receptor Sheds Light on the Activation Mechanism by Lelimousin, Mickael G., Limongelli, Vittorio, Sansom, Mark S.P.

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