Search Results - "Lelianova, Vera"

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities by Silva, John-Paul, Lelianova, Vera G, Ermolyuk, Yaroslav S, Vysokov, Nickolai, Hitchen, Paul G, Berninghausen, Otto, Rahman, M. Atiqur, Zangrandi, Alice, Fidalgo, Sara, Tonevitsky, Alexander G, Dell, Anne, Volynski, Kirill E, Ushkaryov, Yuri A

“…Latrophilin 1 (LPH1), a neuronal receptor of α-latrotoxin, is implicated in neurotransmitter release and control of presynaptic Ca²⁺. As an "adhesion…”
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ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model by Vitobello, Antonio, Mazel, Benoit, Lelianova, Vera G., Zangrandi, Alice, Petitto, Evelina, Suckling, Jason, Salpietro, Vincenzo, Meyer, Robert, Elbracht, Miriam, Kurth, Ingo, Eggermann, Thomas, Benlaouer, Ouafa, Lall, Gurprit, Tonevitsky, Alexander G., Scott, Daryl A., Chan, Katie M., Rosenfeld, Jill A., Nambot, Sophie, Safraou, Hana, Bruel, Ange-Line, Denommé-Pichon, Anne-Sophie, Tran Mau-Them, Frédéric, Philippe, Christophe, Duffourd, Yannis, Guo, Hui, Petersen, Andrea K., Granger, Leslie, Crunk, Amy, Bayat, Allan, Striano, Pasquale, Zara, Federico, Scala, Marcello, Thomas, Quentin, Delahaye, Andrée, de Sainte Agathe, Jean-Madeleine, Buratti, Julien, Kozlov, Serguei V., Faivre, Laurence, Thauvin-Robinet, Christel, Ushkaryov, Yuri

“…ADGRL1 (latrophilin 1), a well-characterized adhesion G protein-coupled receptor, has been implicated in synaptic development, maturation, and activity…”
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Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones by Vysokov, Nickolai V, Silva, John-Paul, Lelianova, Vera G, Suckling, Jason, Cassidy, John, Blackburn, Jennifer K, Yankova, Natalia, Djamgoz, Mustafa Ba, Kozlov, Serguei V, Tonevitsky, Alexander G, Ushkaryov, Yuri A

“…A presynaptic adhesion G-protein-coupled receptor, latrophilin-1, and a postsynaptic transmembrane protein, Lasso/teneurin-2, are implicated in trans-synaptic…”
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The Mechanism of Regulated Release of Lasso/Teneurin-2 by Vysokov, Nickolai V, Silva, John-Paul, Lelianova, Vera G, Ho, Claudia, Djamgoz, Mustafa B, Tonevitsky, Alexander G, Ushkaryov, Yuri A

“…Teneurins are large cell-surface receptors involved in axon guidance. Teneurin-2 (also known as latrophilin-1-associated synaptic surface organizer (Lasso))…”
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Catching Latrophilin With Lasso: A Universal Mechanism for Axonal Attraction and Synapse Formation by Ushkaryov, Yuri A, Lelianova, Vera, Vysokov, Nickolai V

“…Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue. As…”
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Functional Cross-interaction of the Fragments Produced by the Cleavage of Distinct Adhesion G-protein-coupled Receptors by Silva, John-Paul, Lelianova, Vera, Hopkins, Colin, Volynski, Kirill E., Ushkaryov, Yuri

“…The unusual adhesion G-protein-coupled receptors (aGPCRs) contain large extracellular N-terminal domains, which resemble cell-adhesion receptors, and…”
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Latrophilin fragments behave as independent proteins that associate and signal on binding of LTX(N4C) by Volynski, Kirill E, Silva, John-Paul, Lelianova, Vera G, Atiqur Rahman, M, Hopkins, Colin, Ushkaryov, Yuri A

“…Heptahelical, or G-protein-coupled, receptors control many cellular functions and normally consist of one polypeptide chain. In contrast, heptahelical…”
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Latrophilin fragments behave as independent proteins that associate and signal on binding of LTXN4C by Volynski, Kirill E, Silva, John-Paul, Lelianova, Vera G, Atiqur Rahman, M, Hopkins, Colin, Ushkaryov, Yuri A

“…Heptahelical, or G‐protein‐coupled, receptors control many cellular functions and normally consist of one polypeptide chain. In contrast, heptahelical…”
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Functional Cross-interaction of the Fragments Produced by the Cleavage of Distinct Adhesion G-protein-coupled ReceptorsS by Silva, John-Paul, Lelianova, Vera, Hopkins, Colin, Volynski, Kirill E., Ushkaryov, Yuri

“…The unusual adhesion G-protein-coupled receptors (aGPCRs) contain large extracellular N-terminal domains, which resemble cell-adhesion receptors, and…”
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α-Latrotoxin Receptor, Latrophilin, Is a Novel Member of the Secretin Family of G Protein-coupled Receptors by Lelianova, Vera G., Davletov, Bazbek A., Sterling, Alistair, Rahman, M. Atiqur, Grishin, Eugene V., Totty, Nicholas F., Ushkaryov, Yuri A.

“…α-Latrotoxin (LTX) stimulates massive exocytosis of synaptic vesicles and may help to elucidate the mechanism of regulation of neurosecretion. We have recently…”
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alpha-Latrotoxin, acting via two Ca2+-dependent pathways, triggers exocytosis of two pools of synaptic vesicles by Ashton, A C, Volynski, K E, Lelianova, V G, Orlova, E V, Van Renterghem, C, Canepari, M, Seagar, M, Ushkaryov, Y A

“…alpha-Latrotoxin stimulates three types of [(3)H]gamma-aminobutyric acid and [(14)C]glutamate release from synaptosomes. The Ca(2+)-independent component (i)…”
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The latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution by Matsushita, Hiroaki, Lelianova, Vera G., Ushkaryov, Yuri A.

“…Latrophilin is a brain-specific Ca 2+-independent receptor of α-latrotoxin, a potent presynaptic neurotoxin. We now report the finding of two novel latrophilin…”
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Vesicle exocytosis stimulated by α-latrotoxin is mediated by latrophilin and requires both external and stored Ca2 by Davletov, Bazbek A., Meunier, Frédéric A., Ashton, Anthony C., Matsushita, Hiroaki, Hirst, Warren D., Lelianova, Vera G., Wilkin, Graham P., Dolly, J.Oliver, Ushkaryov, Yuri A.

“…α‐Latrotoxin (LTX) stimulates massive neurotransmitter release by two mechanisms: Ca2+‐dependent and ‐independent. Our studies on norepinephrine secretion from…”
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Isolation and biochemical characterization of a Ca2+-independent alpha-latrotoxin-binding protein by Davletov, B A, Shamotienko, O G, Lelianova, V G, Grishin, E V, Ushkaryov, Y A

“…alpha-Latrotoxin, a black widow spider neurotoxin, can bind to high affinity receptors on the presynaptic plasma membrane and stimulate massive…”
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Latrophilin fragments behave as independent proteins that associate and signal on binding of LTX N4C by Ushkaryov, Yuri A, Volynski, Kirill E, Silva, John-Paul, Lelianova, Vera G, Atiqur Rahman, M, Hopkins, Colin

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α-Latrotoxin forms calcium-permeable membrane pores via interactions with latrophilin or neurexin by Van Renterghem, Catherine, Iborra, Cécile, Martin-Moutot, Nicole, Lelianova, Vera, Ushkaryov, Yuri, Seagar, Michael

“…In order to explore the mechanisms by which α‐latrotoxin activates neurotransmitter release, we have characterized its effects by patch‐clamp methods on cells…”
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(Alpha)-latrotoxin forms calcium-permeable membrane pores via interactions with latrophilin or neurexin by Catherine Van Renterghem, Iborra, Cecile, Martin-Moutot, Nicole, Lelianova, Vera

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Latrophilin, Neurexin, and Their Signaling-deficient Mutants Facilitate α-Latrotoxin Insertion into Membranes but Are Not Involved in Pore Formation by Volynski, Kirill E., Meunier, Frédéric A., Lelianova, Vera G., Dudina, Ekaterina E., Volkova, Tatyana M., Rahman, M. Atiqur, Manser, Catherine, Grishin, Eugene V., Dolly, J. Oliver, Ashley, Richard H., Ushkaryov, Yuri A.

“…Pure α-latrotoxin is very inefficient at forming channels/pores in artificial lipid bilayers or in the plasma membrane of non-secretory cells. However, the…”
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The postweld heat-treatment response of simulated coarse-grained heat-affected zones in a new ferritic steel by NAWROCKI, J. G, DUPONT, J. N, ROBINO, C. V, MARDER, A. R

“…Although the composition of HCM2S is different from conventional 2.25Cr-1Mo steel, current welding codes apply the same PWHT schedules to each alloy. However,…”
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Vesicle exocytosis stimulated by α-latrotoxin is mediated by latrophilin and requires both external and stored Ca 2 by Ushkaryov, Yuri A, Davletov, Bazbek A, Meunier, Frédéric A, Ashton, Anthony C, Matsushita, Hiroaki, Hirst, Warren D, Lelianova, Vera G, Wilkin, Graham P, Dolly, J.Oliver

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