Search Results - "Lelièvre Pégorier, Martine"
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The magnitude of nephron number reduction mediates intrauterine growth-restriction-induced long term chronic renal disease in the rat. A comparative study in two experimental models
Published in Journal of translational medicine (30-11-2016)“…Intrauterine growth restriction (IUGR) is a risk factor for hypertension (HT) and chronic renal disease (CRD). A reduction in the nephron number is proposed to…”
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2
Long Lasting Microvascular Tone Alteration in Rat Offspring Exposed In Utero to Maternal Hyperglycaemia
Published in PloS one (12-01-2016)“…Epidemiologic studies have demonstrated that cardiovascular risk is not only determined by conventional risk factors in adulthood, but also by early life…”
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3
MMP9 Limits Apoptosis and Stimulates Branching Morphogenesis During Kidney Development
Published in Journal of the American Society of Nephrology (01-10-2009)“…Early events in kidney organogenesis involve reciprocal interactions between the ureteric bud and the metanephric mesenchyme, which lead to remodeling of the…”
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4
Compensatory renal growth after unilateral or subtotal nephrectomy in the ovine fetus
Published in Pediatric research (01-12-2013)“…Background: Clinical and experimental studies show that unilateral (1/2Nx) and subtotal nephrectomy (5/6Nx) in adults result in compensatory renal growth…”
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Kidney Gene Expression Analysis in a Rat Model of Intrauterine Growth Restriction Reveals Massive Alterations of Coagulation Genes
Published in Endocrinology (Philadelphia) (01-11-2007)“…In this study, low birth weight was induced in rats by feeding the dams with a low-protein diet during pregnancy. Kidneys from the fetuses at the end of…”
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6
Exposure to Maternal Diabetes Induces Salt-Sensitive Hypertension and Impairs Renal Function in Adult Rat Offspring
Published in Diabetes (New York, N.Y.) (01-08-2008)“…Exposure to Maternal Diabetes Induces Salt-Sensitive Hypertension and Impairs Renal Function in Adult Rat Offspring Touria Nehiri 1 , Jean-Paul Duong Van Huyen…”
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7
Neonatal Oxygen Exposure in Rats Leads to Cardiovascular and Renal Alterations in Adulthood
Published in Hypertension (Dallas, Tex. 1979) (01-11-2008)“…Long-term vascular and renal consequences of neonatal oxidative injury are unknown. Using a rat model, we sought to investigate whether vascular function and…”
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Mild vitamin A deficiency leads to inborn nephron deficit in the rat
Published in Kidney international (01-11-1998)“…Mild vitamin A deficiency leads to inborn nephron deficit in the rat. Vitamin A plays a critical role in fetal organogenesis, and its severe deficiency during…”
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Hyperoxia exposure impairs nephrogenesis in the neonatal rat: role of HIF-1α
Published in PloS one (17-12-2013)“…Preterm neonates are exposed at birth to high oxygen concentrations relative to the intrauterine environment. We have previously shown in a rat model that a…”
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10
Role of retinoids in renal development: pathophysiological implication
Published in Current opinion in nephrology and hypertension (01-01-1999)“…Vitamin A closely modulates nephron endowment at birth. It is also required for the development of renal vasculature. Fetal vitamin A status may thus be…”
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Early postnatal overfeeding induces early chronic renal dysfunction in adult male rats
Published in American journal of physiology. Renal physiology (01-10-2009)“…Low birth weight is associated with an increased risk of hypertension and renal dysfunction at adulthood. Such an association has been shown to involve a…”
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12
Effects of early postnatal hypernutrition on nephron number and long-term renal function and structure in rats
Published in American journal of physiology. Renal physiology (01-12-2007)“…Various antenatal events impair nephrogenesis in humans as well as in several animal models. The consecutive low nephron endowment may contribute to an…”
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13
Effects of mild vitamin a deficiency on lung maturation in newborn rats: a morphometric and morphologic study
Published in Biology of the neonate (01-01-2004)“…To evaluate the effects of a 60% vitamin A deficiency (VAD) on the two postnatal stages of lung development: alveolarization and microvascular maturation…”
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Altered Nephrogenesis Due to Maternal Diabetes Is Associated With Increased Expression of IGF-II/Mannose-6-Phosphate Receptor in the Fetal Kidney
Published in Diabetes (New York, N.Y.) (01-05-2001)“…Altered Nephrogenesis Due to Maternal Diabetes Is Associated With Increased Expression of IGF-II/Mannose-6-Phosphate Receptor in the Fetal Kidney Kaouthar Amri…”
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Midkine is involved in kidney development and in its regulation by retinoids
Published in Journal of the American Society of Nephrology (01-03-2002)“…In the kidney, in which development depends on epithelial-mesenchymal interactions, it has been shown that retinoids modulate nephrogenesis in a dose-dependent…”
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Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies
Published in Diabetes (New York, N.Y.) (01-11-1999)“…Adverse effects of hyperglycemia on kidney development in rats: in vivo and in vitro studies. K Amri , N Freund , J Vilar , C Merlet-Bénichou and M…”
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Mild Vitamin A Deficiency Delays Fetal Lung Maturation in the Rat
Published in American journal of respiratory cell and molecular biology (01-07-1999)“…During late pregnancy, the fetal lung stores surfactant in preparation for extrauterine life. Surfactant deficiency, most often due to prematurity,…”
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In Utero Exposure to Maternal Diabetes Impairs Vascular Expression of Prostacyclin Receptor in Rat Offspring
Published in Diabetes (New York, N.Y.) (01-10-2010)“…To evaluate modifications of arterial structure, gene expression, and function in our model of rats exposed to maternal diabetes. Morphometric analyses of…”
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Intrauterine growth retardation leads to a permanent nephron deficit in the rat
Published in Pediatric nephrology (Berlin, West) (01-04-1994)“…Intrauterine growth retardation (IUGR) was induced in Sprague-Dawley rats by partial artery ligation of one uterine horn in the mother on day 17 of gestation…”
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The (pro)renin receptor: biochemistry and ontogeny
Published in Journal of the renin-angiotensin-aldosterone system (01-03-2008)Get full text
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