Search Results - "Lelièvre, Eric"

Chemotherapy-induced senescence, an adaptive mechanism driving resistance and tumor heterogeneity by Guillon, Jordan, Petit, Coralie, Toutain, Bertrand, Guette, Catherine, Lelièvre, Eric, Coqueret, Olivier

“…Senescence is activated in response to chemotherapy to prevent the propagation of cancer cells. In transformed cells, recent studies have shown that this…”
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Protective role of the mitochondrial fusion protein OPA1 in hypertension by Robert, Pauline, Nguyen, Phuc Minh Chau, Richard, Alexis, Grenier, Céline, Chevrollier, Arnaud, Munier, Mathilde, Grimaud, Linda, Proux, Coralyne, Champin, Tristan, Lelièvre, Eric, Sarzi, Emmanuelle, Vessières, Emilie, Henni, Samir, Prunier, Delphine, Reynier, Pascal, Lenaers, Guys, Fassot, Céline, Henrion, Daniel, Loufrani, Laurent

“…Hypertension is associated with excessive reactive oxygen species (ROS) production in vascular cells. Mitochondria undergo fusion and fission, a process…”
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Proteomics Approaches to Define Senescence Heterogeneity and Chemotherapy Response by Petit, Coralie, Guillon, Jordan, Toutain, Bertrand, Boissard, Alice, Patsouris, Anne, Lelièvre, Eric, Guette, Catherine, Coqueret, Olivier

“…In primary cells, senescence induces a permanent proliferative arrest to prevent the propagation of malignant cells. However, the outcome of senescence is more…”
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Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment by Guillon, Jordan, Petit, Coralie, Moreau, Marie, Toutain, Bertrand, Henry, Cécile, Roché, Henry, Bonichon-Lamichhane, Nathalie, Salmon, Jean Paul, Lemonnier, Jérôme, Campone, Mario, Verrièle, Véronique, Lelièvre, Eric, Guette, Catherine, Coqueret, Olivier

“…Senescence is a tumor-suppressive mechanism induced by telomere shortening, oncogenes, or chemotherapy treatment. Although it is clear that this suppressive…”
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Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy by Le Duff, Mélanie, Gouju, Julien, Jonchère, Barbara, Guillon, Jordan, Toutain, Bertrand, Boissard, Alice, Henry, Cécile, Guette, Catherine, Lelièvre, Eric, Coqueret, Olivier

“…Senescence is a tumor suppressive mechanism that induces a permanent proliferative arrest in response to an oncogenic insult or to the genotoxic stress induced…”
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Long Lasting Microvascular Tone Alteration in Rat Offspring Exposed In Utero to Maternal Hyperglycaemia by Vessières, Emilie, Dib, Abdallah, Bourreau, Jennifer, Lelièvre, Eric, Custaud, Marc-Antoine, Lelièvre-Pégorier, Martine, Loufrani, Laurent, Henrion, Daniel, Fassot, Céline

“…Epidemiologic studies have demonstrated that cardiovascular risk is not only determined by conventional risk factors in adulthood, but also by early life…”
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Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling by Imler, Jean-Luc, Gay, Nicholas J, Weber, Alexander N R, Ray, Keith P, Lelièvre, Eric, Hoffmann, Jules A, Morse, Mary A, Tauszig-Delamasure, Servane, Gascan, Hugues

“…The extracellular protein Spätzle is required for activation of the Toll signaling pathway in the embryonic development and innate immune defense of…”
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O-GlcNAcylation Links Nutrition to the Epigenetic Downregulation of UNC5A during Colon Carcinogenesis by Decourcelle, Amélie, Very, Ninon, Djouina, Madjid, Loison, Ingrid, Thévenet, Julien, Body-Malapel, Mathilde, Lelièvre, Eric, Coqueret, Olivier, Leprince, Dominique, Yazidi-Belkoura, Ikram El, Dehennaut, Vanessa

“…While it is now accepted that nutrition can influence the epigenetic modifications occurring in colorectal cancer (CRC), the underlying mechanisms are not…”
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Overexpression of a Medicago truncatula stress-associated protein gene (MtSAP1) leads to nitric oxide accumulation and confers osmotic and salt stress tolerance in transgenic tobacco by Charrier, Aurélie, Planchet, Elisabeth, Cerveau, Delphine, Gimeno-Gilles, Christine, Verdu, Isabelle, Limami, Anis M., Lelièvre, Eric

“…The impact of Medicago truncatula stress-associated protein gene (MtSAP1) overexpression has been investigated in Nicotiana tabacum transgenic seedlings. Under…”
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ABA-Mediated Inhibition of Germination Is Related to the Inhibition of Genes Encoding Cell-Wall Biosynthetic and Architecture: Modifying Enzymes and Structural Proteins in Medicago truncatula Embryo Axis by Gimeno-Gilles, Christine, Lelièvre, Eric, Viau, Laure, Malik-Ghulam, Mustafa, Ricoult, Claudie, Niebel, Andreas, Leduc, Nathalie, Limami, Anis M.

“…Radicle emergence and reserves mobilization are two distinct programmes that are thought to control germination. Both programs are influenced by abscissic acid…”
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Medicago truncatula stress associated protein 1 gene (MtSAP1) overexpression confers tolerance to abiotic stress and impacts proline accumulation in transgenic tobacco by Charrier, Aurélie, Lelièvre, Eric, Limami, Anis M., Planchet, Elisabeth

“…Stress associated proteins (SAP) have been already reported to play a role in tolerance acquisition of some abiotic stresses. In the present study, the role of…”
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gene encoding a protein with a proline-rich domain (MtPPRD1), revealed by suppressive subtractive hybridization (SSH), is specifically expressed in the Medicago truncatula embryo axis during germination by Bouton, Sophie, Viau, Laure, Lelièvre, Eric, Limami, Anis M

“…A gene MtPPRD1, encoding a protein of 132 amino acids containing a proline-rich domain (PRD), has been revealed by suppressive subtractive hybridization (SSH)…”
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CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex by Gauchat, Jean-François, Elson, Greg C. A, Lelièvre, Eric, Guillet, Catherine, Chevalier, Sylvie, Plun-Favreau, Hélène, Froger, Josy, Suard, Isabelle, de Coignac, Amélie Benoit, Delneste, Yves, Bonnefoy, Jean-Yves, Gascan, Hugues

“…Ciliary neurotrophic factor (CNTF) is a cytokine supporting the differentiation and survival of various cell types in the peripheral and central nervous…”
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Anterior gradient protein 2 is a marker of tumor aggressiveness in breast cancer and favors chemotherapy‑induced senescence escape by Maarouf, Amine, Boissard, Alice, Henry, Cécile, Leman, Géraldine, Coqueret, Olivier, Guette, Catherine, Lelièvre, Eric

“…Among the different chemotherapies available, genotoxic drugs are widely used. In response to these drugs, particularly doxorubicin, tumor cells can enter into…”
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A stress-associated protein containing A20/AN1 zing-finger domains expressed in Medicago truncatula seeds by Gimeno-Gilles, Christine, Gervais, Marie-Laure, Planchet, Elisabeth, Satour, Pascale, Limami, Anis M., Lelievre, Eric

“…MtSAP1 ( Medicago truncatula stress-associated protein 1) was revealed as a down-regulated gene by suppressive subtractive hybridization between two mRNA…”
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Recruitment of STAT3 for Production of IL-10 by Colon Carcinoma Cells Induced by Macrophage-Derived IL-6 by Herbeuval, Jean-Philippe, Lelievre, Eric, Lambert, Claude, Dy, Michel, Genin, Christian

“…The immunosuppressive cytokine IL-10 is associated with poor prognosis in colon cancer. Although macrophages are involved in antitumor defenses, production of…”
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Sphingomyelin nanosystems decorated with TSP-1 derived peptide targeting senescent cells by Jatal, Raneem, Mendes Saraiva, Sofia, Vázquez-Vázquez, Carlos, Lelievre, Eric, Coqueret, Olivier, López-López, Rafael, de la Fuente, María

“…[Display omitted] •Sphingomyelin nanosystems surface-decorated with 4N1Ks peptide were successfully prepared by single-step ethanol injection method.•The…”
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Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component by Lelièvre, E, Plun-Favreau, H, Chevalier, S, Froger, J, Guillet, C, Elson, G C, Gauchat, J F, Gascan, H

“…Ciliary neurotrophic factor (CNTF) is a cytokine supporting the differentiation and survival of a number of neural cell types. Its receptor complex consists of…”
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GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor by Diveu, Caroline, Lelièvre, Eric, Perret, David, Lak-Hal, Anne-Hélène Lagrue, Froger, Josy, Guillet, Catherine, Chevalier, Sylvie, Rousseau, François, Wesa, Amy, Preisser, Laurence, Chabbert, Marie, Gauchat, Jean-François, Galy, Anne, Gascan, Hugues, Morel, Alain

“…We describe a novel cytokine receptor named GP130 Like receptor, or GPL, that displays similarities with the interleukin-6 and interleukin-12 family of…”
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The ciliary neurotrophic factor receptor α component induces the secretion of and is required for functional responses to cardiotrophin-like cytokine by Plun-Favreau, Hélène, Elson, Greg, Chabbert, Marie, Froger, Josy, deLapeyrière, Odile, Lelièvre, Eric, Guillet, Catherine, Hermann, Jacques, Gauchat, Jean-François, Gascan, Hugues, Chevalier, Sylvie

“…Ciliary neurotrophic factor (CNTF) is involved in the survival of a number of different neural cell types, including motor neurons. CNTF functional responses…”
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