Search Results - "Leleu, Damien"
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Cholesterol and HIF-1α: Dangerous Liaisons in Atherosclerosis
Published in Frontiers in immunology (21-03-2022)“…HIF-1α exerts both detrimental and beneficial actions in atherosclerosis. While there is evidence that HIF-1α could be pro-atherogenic within the atheromatous…”
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A Method for Isolating and Culturing Skin Cells: Application to Endothelial Cells, Fibroblasts, Keratinocytes, and Melanocytes From Punch Biopsies in Systemic Sclerosis Skin
Published in Frontiers in immunology (07-10-2020)“…Systemic Sclerosis (SSc) is a complex auto-immune connective tissue disease combining inflammatory, vasculopathic and fibrotic manifestations. Skin effectively…”
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Inflammation and oxidative stress markers in type 2 diabetes patients with Advanced Carotid atherosclerosis
Published in Cardiovascular diabetology (14-09-2023)“…Abstract Background Type 2 diabetes mellitus (T2DM) is a major global health issue and a significant risk factor for atherosclerosis. Atherosclerosis in T2DM…”
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Elevated Circulatory Levels of Microparticles Are Associated to Lung Fibrosis and Vasculopathy During Systemic Sclerosis
Published in Frontiers in immunology (23-10-2020)“…Microparticles (MPs) are vesicular structures that derive from multiple cellular sources. MPs play important roles in intercellular communication, regulation…”
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A case of functional vitamin B12 deficiency after recreational nitrous oxide use
Published in Biochemia Medica (15-02-2024)“…The recreational use of nitrous oxide as laughing gas becomes a real public health issue among adolescents and young adults. Chronic use is deleterious and can…”
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Detection of the novel allele, HLA‐A32:165, in a French individual by next‐generation sequencing
Published in HLA : immune response genetics (01-12-2022)“…The HLA‐A*32:165 allele has one non‐synonymous nucleotide change from HLA‐A*32:01:01 at nucleotide 242 in exon 2…”
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Impact of liver X receptor inhibition on macrophage cholesterol homeostasis and inflammatory response in atherosclerosis
Published in Atherosclerosis (01-08-2024)Get full text
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TGFβ promotes low IL10-producing ILC2 with profibrotic ability involved in skin fibrosis in systemic sclerosis
Published in Annals of the rheumatic diseases (01-12-2021)“…Innate lymphoid cells-2 (ILC2) were shown to be involved in the development of lung or hepatic fibrosis. We sought to explore the functional and phenotypic…”
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81-OR: Comparison of Screening Pathways of Advanced Fibrosis Due to MASLD in Diabetology
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Introduction & Objective: Screening for advanced fibrosis (AF) due to metabolic dysfunction-associated steatotic liver disease (MASLD) is recommended in…”
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Negative relationship between eicosapentaenoic acid and inflammatory biomarkers in patients with acute myocardial infarction
Published in Cardiovascular research (13-03-2024)Get full text
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Impaired unsaturated fatty acid elongation alters mitochondrial function and accelerates metabolic dysfunction-associated steatohepatitis progression
Published in Metabolism, clinical and experimental (01-01-2025)“…Although qualitative and quantitative alterations in liver Polyunsaturated Fatty Acids (PUFAs) are observed in MASH in humans, a causal relationship of PUFAs…”
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Interleukin‐1β–Activated Microvascular Endothelial Cells Promote DC‐SIGN–Positive Alternatively Activated Macrophages as a Mechanism of Skin Fibrosis in Systemic Sclerosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2022)“…Objective To characterize the role of interleukin‐1β (IL‐1β) and microvascular endothelial cells (MVECs) in the generation of alternatively activated…”
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Evaluation of pre-operative high dose corticosteroids in elective colorectal surgery and effects on gut barrier function: A phase 2 clinical trial
Published in Surgery Open Digestive Advance (01-06-2024)“…Perioperative inflammation is a predictor of surgical complications and cancer prognosis in surgical oncology. Multimodal protocols are ongoing in order to…”
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A case of functional vitamin B12 deficiency after recreational nitrous oxide use
Published in Biochemia medica (15-02-2024)“…The recreational use of nitrous oxide as laughing gas becomes a real public health issue among adolescents and young adults. Chronic use is deleterious and can…”
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