Search Results - "Leland, Bryan A"

Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks by Leland, Bryan A, Chen, Angela C, Zhao, Amy Y, Wharton, Robert C, King, Megan C

“…Poly(ADP ribose) polymerase inhibitors (PARPi) target cancer cells deficient in homology-directed repair of DNA double-strand breaks (DSBs). In preclinical…”
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Homology-directed repair involves multiple strand invasion cycles in fission yeast by Vines, Amanda J, Cox, Kenneth, Leland, Bryan A, King, Megan C

“…Homology-directed repair of DNA double-strand breaks (DSBs) represents a highly faithful pathway. Non-crossover repair dominates in mitotically growing cells,…”
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Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription by Ogawa, Lisa M, Buhagiar, Amber F, Abriola, Laura, Leland, Bryan A, Surovtseva, Yulia V, Baserga, Susan J

“…Nucleoli are dynamic nuclear condensates in eukaryotic cells that originate through ribosome biogenesis at loci that harbor the ribosomal DNA. These loci are…”
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Using LacO arrays to monitor DNA double-strand break dynamics in live Schizosaccharomyces pombe cells by Leland, Bryan A, King, Megan C

“…LacO arrays, when combined with LacI-GFP, have been a valuable tool for studying nuclear architecture and chromatin dynamics. Here, we outline an experimental…”
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Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways by Klein, Hannah L, Bačinskaja, Giedrė, Che, Jun, Cheblal, Anais, Elango, Rajula, Epshtein, Anastasiya, Fitzgerald, Devon M, Gómez-González, Belén, Khan, Sharik R, Kumar, Sandeep, Leland, Bryan A, Marie, Léa, Mei, Qian, Miné-Hattab, Judith, Piotrowska, Alicja, Polleys, Erica J, Putnam, Christopher D, Radchenko, Elina A, Saada, Anissia Ait, Sakofsky, Cynthia J, Shim, Eun Yong, Stracy, Mathew, Xia, Jun, Yan, Zhenxin, Yin, Yi, Aguilera, Andrés, Argueso, Juan Lucas, Freudenreich, Catherine H, Gasser, Susan M, Gordenin, Dmitry A, Haber, James E, Ira, Grzegorz, Jinks-Robertson, Sue, King, Megan C, Kolodner, Richard D, Kuzminov, Andrei, Lambert, Sarah Ae, Lee, Sang Eun, Miller, Kyle M, Mirkin, Sergei M, Petes, Thomas D, Rosenberg, Susan M, Rothstein, Rodney, Symington, Lorraine S, Zawadzki, Pawel, Kim, Nayun, Lisby, Michael, Malkova, Anna

“…Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in…”
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Modeling Fluorescently Tagged DNA and RNA Oligonucleotides for Direct Comparison to Fluorescence-Detected Resonance Energy Transfer (FRET) Experiments by Speelman, Amy L., Ortega, Arcelia S., Paul, David A., Leland, Bryan A., Krueger, Brent P.

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