Abnormal cervical cytology amongst women infected with human immunodeficiency virus in Limpopo province, South Africa

Abnormal cervical cytology amongst women infected with human immunodeficiency virus in Limpopo province, South Africa

Background: Cervical cancer remains the major public problem worldwide and the most common gynaecological malignancy in the developing world, particularly in sub-Saharan Africa.Aim: To determine the prevalence of abnormal cervical cytology amongst women with and without human immunodeficiency virus...

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Bibliographic Details
Published in:African journal of primary health care & family medicine Vol. 12; no. 1; pp. 1 - 4
Main Authors: Ntuli, Samuel T, Maimela, Eric, Skaal, Linda, Mogale, Mabina, Lekota, Provia
Format: Journal Article
Language:English
Published: Cape Town AOSIS 2020
African Online Scientific Information Systems (Pty) Ltd t/a AOSIS
AOSIS (Pty) Ltd
AOSIS Publishing
Subjects:
Abnormal cytology
Age groups
Biology
Cellular biology
Cervical cancer
Developing countries
Farmworkers
Health Care Sciences & Services
HIV
HIV patients
Human immunodeficiency virus
Human papillomavirus
Immunization
Laboratories
Limpopo province
Medical screening
Medicine, General & Internal
Migrant workers
Papillomavirus infections
Prevalence
Scientific Letter
Sex industry
Women
Womens health
South Africa
Nigeria
Tanzania
human immunodeficiency virus
Prevalence
abnormal cytology
cervical cancer
Limpopo province
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Summary:Background: Cervical cancer remains the major public problem worldwide and the most common gynaecological malignancy in the developing world, particularly in sub-Saharan Africa.Aim: To determine the prevalence of abnormal cervical cytology amongst women with and without human immunodeficiency virus (HIV) and examine the association between HIV and histological grading.Setting: The study was conducted in Limpopo province, which is the northernmost province of South Africa. The province has five district municipalities with one tertiary, five regional and thirty four district hospitals.Methods: We retrospectively reviewed cervical cancer cases in Limpopo province (LP) of South Africa, using data collected routinely by the National Health Laboratory Services (NHLS). The data on smears submitted for cytology between 2013 and 2015 were extracted from the Central Data Warehouse (CDW) database.Results: A total of 84 466 women were screened for cervical cytology smears. Their mean age was 39.8 ± 13.6 years, with range from 15 to 113 years; 77.2% were in the age group 30 years and older and 19.6% had an abnormal cervical cytology result. Overall, 46.4% of the women screened for cervical cancer were HIV infected. A significantly higher proportion of HIVpositive women had abnormal cytology than HIV-negative women (31.8% vs. 9.2%). Conclusion: The prevalence of abnormal cytology amongst HIV-positive women is relatively high, and the risk appears to be significantly greater in all age groups. This finding highlights the need to ascertain HIV status of all women presenting with cervical cancer.
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ISSN:2071-2928
2071-2936
2071-2936
DOI:10.4102/phcfm.v12i1.2215