Search Results - "Lekka, Marilena E."
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Enrichment of Olive Oils with Natural Bioactive Compounds from Aromatic and Medicinal Herbs: Phytochemical Analysis and Antioxidant Potential
Published in Molecules (Basel, Switzerland) (01-03-2024)“…Olive oil and herbs, two key components of the Mediterranean diet, are known for their beneficial effects on humans. In our study, we incorporated aromatic and…”
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In Vitro Evaluation of the Antibacterial Activity of the Peptide Fractions Extracted from the Hemolymph of Hermetia illucens (Diptera: Stratiomyidae)
Published in Insects (Basel, Switzerland) (15-05-2023)“…Antimicrobial peptides (AMPs) are a chemically and structurally heterogeneous family of molecules produced by a large variety of living organisms, whose…”
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Deciphering the Relationship Between Free and Vesicular Hemoglobin in Stored Red Blood Cell Units
Published in Frontiers in physiology (08-02-2022)“…Red blood cells (RBCs) release hemoglobin (Hb)-containing extracellular vesicles (EVs) throughout their lifespan in the circulation, and especially during…”
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Secretory Phospholipase A2-IIA Protein and mRNA Pools in Extracellular Vesicles of Bronchoalveolar Lavage Fluid from Patients with Early Acute Respiratory Distress Syndrome: A New Perception in the Dissemination of Inflammation?
Published in Pharmaceuticals (Basel, Switzerland) (23-11-2020)“…Secretory phospholipase-IIA A2 (sPLA2-IIA) is expressed in a variety of cell types under inflammatory conditions. Its presence in the bronchoalveolar lavage…”
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Docosahexaenoic Acid Inhibits Proliferation of EoL-1 Leukemia Cells and Induces Cell Cycle Arrest and Cell Differentiation
Published in Nutrients (07-03-2019)“…Τhe effect of docosahexaenoic acid (DHA, an omega-3 polyunsaturated fatty acid) upon the proliferation of EoL-1 (Eosinophilic leukemia) cell line was assessed,…”
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Red Blood Cell Proteasome in Beta-Thalassemia Trait: Topology of Activity and Networking in Blood Bank Conditions
Published in Membranes (Basel) (17-09-2021)“…Proteasomes are multi-catalytic complexes with important roles in protein control. Their activity in stored red blood cells (RBCs) is affected by both storage…”
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Dipalmitoyl-Phosphatidylcholine Biosynthesis is Induced by Non-Injurious Mechanical Stretch in a Model of Alveolar Type II Cells
Published in Lipids (01-08-2013)“…Dipalmitoylphosphatidylcholine, (DP-PtdCho), the major phospholipid component of lung surfactant is biosynthesized via a de novo pathway, the last step of…”
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Biochemical parameters of bronchoalveolar lavage fluid in fat embolism
Published in Intensive care medicine (01-01-2006)“…To identify diagnostic markers distinguishing between acute lung injury/acute respiratory distress syndrome (ALI/ARDS) due to fat embolism syndrome (FES) and…”
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Inhaled activated protein C protects mice from ventilator-induced lung injury
Published in Critical care (London, England) (01-01-2010)“…Activated Protein C (APC), an endogenous anticoagulant, improves tissue microperfusion and endothelial cell survival in systemic inflammatory states such as…”
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10
Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
Published in ACS nano (26-04-2016)“…Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are…”
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Phospholipase A2 subclasses in acute respiratory distress syndrome
Published in Biochimica et biophysica acta (01-10-2009)“…Phospholipases A2 (PLA2) catalyse the cleavage of fatty acids esterified at the sn-2 position of glycerophospholipids. In acute lung injury-acute respiratory…”
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12
Screening of mushrooms bioactivity: piceatannol was identified as a bioactive ingredient in the order Cantharellales
Published in European food research & technology (01-05-2018)“…Wild edible mushroom species are appreciated for consumption due to their high nutritional value. The aim of the present study was to examine in vitro…”
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Phospholipases A2 as biomarkers in acute respiratory distress syndrome
Published in Biomedical journal (01-12-2021)“…Acute respiratory distress syndrome (ARDS) is a multifactorial life-threatening lung injury, characterized by diffuse lung inflammation and increased…”
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Study of potent cytotoxic activity of Helleborus cyclophyllus Boiss against a human adenocarcinoma cell line
Published in Cytotechnology (Dordrecht) (01-12-2020)“…Helleborus cyclophyllus Boiss is a rhizomatous plant species, with strong allelochemical properties, that has been used since ancient times for its therapeutic…”
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Effect of azithromycin on the LPS-induced production and secretion of phospholipase A2 in lung cells
Published in Biochimica et biophysica acta (01-07-2015)“…Azithromycin is a member of macrolides, utilized in the treatment of infections. Independently, these antibiotics also possess anti-inflammatory and…”
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Cationic amphipathic peptide analogs of cathelicidin LL‐37 as a probe in the development of antimicrobial/anticancer agents
Published in Journal of peptide science (01-07-2020)“…Cathelicidin LL‐37 belongs to the class of human defense peptides and is overexpressed in many cancers. Segments of LL‐37 derived through biochemical processes…”
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Phospholipases A2 and platelet-activating-factor acetylhydrolase in patients with acute respiratory distress syndrome
Published in Critical care medicine (01-04-2005)“…OBJECTIVE:Phospholipases A2 (PLA2) comprise a family of enzymes probably implicated in the development of acute respiratory distress syndrome (ARDS). The aim…”
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Immobilization of Lipid Substrates: Application on Phospholipase A2 Determination
Published in Lipids (01-12-2015)“…The purpose of the study was to assess a fluorimetric assay for the determination of total phospholipase A 2 (PLA 2 ) activity in biological samples…”
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Mild stretch activates cPLA₂ in alveolar type II epithelial cells independently through the MEK/ERK and PI3K pathways
Published in Biochimica et biophysica acta (01-06-2011)“…Alveolar epithelial type II cells (AT II) in which lung surfactant synthesis and secretion take place, are subjected to low magnitude stretch during normal…”
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A Specific Phospholipase C Activity Regulates Phosphatidylinositol Levels in Lung Surfactant of Patients with Acute Respiratory Distress Syndrome
Published in American journal of respiratory cell and molecular biology (01-03-2010)“…Lung surfactant (LS) is a lipid-rich material lining the inside of the lungs. It reduces surface tension at the liquid/air interface and thus, it confers…”
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