Search Results - "Lejnine, S."

Gene expression analysis in serial liver fine needle aspirates by Lejnine, S., Marton, M. J., Wang, I.-M., Howell, B. J., Webber, A. L., Maxwell, J. W., Shire, N., Malkov, V., Lunceford, J., Zeremski, M., Sun, A., Ruddy, M., Talal, A. H.

“…Summary No method with low morbidity presently exists for obtaining serial hepatic gene expression measurements in humans. While hepatic fine needle aspiration…”
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Development and standardization of multiplexed antibody microarrays for use in quantitative proteomics by Perlee, L T, Christiansen, J, Dondero, R, Grimwade, B, Lejnine, S, Mullenix, M, Shao, W, Sorette, M, Tchernev, V T, Patel, D D, Kingsmore, S F

“…Quantitative proteomics is an emerging field that encompasses multiplexed measurement of many known proteins in groups of experimental samples in order to…”
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Conserved Nucleoprotein Structure at the Ends of Vertebrate and Invertebrate Chromosomes by Lejnine, Serguei, Makarov, Vladimir L., Langmore, John P.

“…Eukaryotic chromosomes terminate with telomeres, nucleoprotein structures that are essential for chromosome stability. Vertebrate telomeres consist of terminal…”
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Set of novel tools for PCR primer design by Gorelenkov, V, Antipov, A, Lejnine, S, Daraselia, N, Yuryev, A

“…We have developed a new package of computer programs and algorithms for different PCR applications, including allele-specific PCR, multiplex PCR, and long PCR…”
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Crosslinking of proteins to DNA in human nuclei using a 60 femtosecond 266 nm laser by Lejnine, S., Durfee, G., Murnane, M., Kapteyn, H. C., Makarov, V. L., Langmore, J. P.

“…We developed appropriate conditions to use a laser with 60 femtosecond pulses, a frequency of 1 KHz and a wavelength of 266 nm to efficiently crosslink…”
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In vitro and in vivo reconstitution and stability of vertebrate chromosome ends by Li, Liwu, Lejnine, Serguei, Makarov, Vladimir, Langmore, John P.

“…Telomeres are essential repetitive sequences at the ends of chromosomes that prevent chromosome fusion and degradation. We have successfully recapitulated…”
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A candidate plasma protein classifier to identify Alzheimer's disease by Zhao, Xuemei, Lejnine, Serguei, Spond, Jeffrey, Zhang, Chunsheng, Ramaraj, T C, Holder, Daniel J, Dai, Hongyue, Weiner, Russell, Laterza, Omar F

“…Biomarkers currently used in the aid for the diagnosis of Alzheimer's disease (AD) are cerebrospinal fluid (CSF) protein markers and brain neuroimaging…”
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Nucleosomal organization of telomere-specific chromatin in rat by Makarov, V L, Lejnine, S, Bedoyan, J, Langmore, J P

“…Rat liver interphase chromosomes have telomeres 20-100 kb in length. Micrococcal nuclease digestion of nuclei cleaves telomeres with a uniform 157 bp…”
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Condensation of Rat Telomere-specific Nucleosomal Arrays Containing Unusually Short DNA Repeats and Histone H1 by Bedoyan, Jirair K., Lejnine, Serguei, Makarov, Vladimir L., Langmore, John P.

“…Vertebrate telomeres contain arrays of nucleosomes with unusually short and regular repeat lengths (Makarov, V. L., Lejnine, S., Bedoyan, J., and Langmore, J…”
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