Search Results - "Lejeune, Clara"

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  1. 1

    Comparative Proteomic Analysis of Transcriptional and Regulatory Proteins Abundances in S. lividans and S. coelicolor Suggests a Link between Various Stresses and Antibiotic Production by Clara, Lejeune, David, Cornu, Laila, Sago, Virginie, Redeker, Marie-Joelle, Virolle

    “…and constitute model strains to study the regulation of antibiotics biosynthesis in species since these closely related strains possess the same pathways…”
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    Journal Article
  2. 2

    Expression of genes of the Pho regulon is altered in Streptomyces coelicolor by Millan-Oropeza, Aaron, Henry, Céline, Lejeune, Clara, David, Michelle, Virolle, Marie-Joelle

    Published in Scientific reports (22-05-2020)
    “…Most currently used antibiotics originate from Streptomycetes and phosphate limitation is an important trigger of their biosynthesis. Understanding the…”
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    Journal Article
  3. 3

    A Proteomic Analysis Indicates That Oxidative Stress Is the Common Feature Triggering Antibiotic Production in Streptomyces coelicolor and in the pptA Mutant of Streptomyces lividans by Lejeune, Clara, Sago, Laila, Cornu, David, Redeker, Virginie, Virolle, Marie-Joelle

    Published in Frontiers in microbiology (22-03-2022)
    “…In most species, antibiotic production is triggered in phosphate limitation and repressed in phosphate proficiency. However, the model strain, , escapes this…”
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    Journal Article
  4. 4

    Impact of Phosphate Availability on Membrane Lipid Content of the Model Strains, Streptomyces lividans and Streptomyces coelicolor by Lejeune, Clara, Abreu, Sonia, Chaminade, Pierre, Dulermo, Thierry, David, Michelle, Werten, Sebastiaan, Virolle, Marie-Joelle

    Published in Frontiers in microbiology (22-02-2021)
    “…In this issue we demonstrated that the phospholipid content of varies greatly with Pi availability being was much lower in Pi limitation than in Pi proficiency…”
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    Journal Article
  5. 5

    Impact of the Deletion of Genes of the Nitrogen Metabolism on Triacylglycerol, Cardiolipin and Actinorhodin Biosynthesis in Streptomyces coelicolor by Abreu, Sonia, Lejeune, Clara, David, Michelle, Chaminade, Pierre, Virolle, Marie-Joelle

    Published in Microorganisms (Basel) (30-07-2024)
    “…Since nitrogen limitation is known to be an important trigger of triacylglycerol (TAG) accumulation in most microorganisms, we first assessed the global lipid…”
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    Journal Article
  6. 6

    Consequences of the deletion of the major specialized metabolite biosynthetic pathways of Streptomyces coelicolor on the metabolome and lipidome of this strain by Lejeune, Clara, Abreu, Sonia, Guérard, Florence, Askora, Ahmed, David, Michelle, Chaminade, Pierre, Gakière, Bertrand, Virolle, Marie‐Joelle

    Published in Microbial biotechnology (01-08-2024)
    “…Chassis strains, derived from Streptomyces coelicolor M145, deleted for one or more of its four main specialized metabolites biosynthetic pathways (CPK, CDA,…”
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    Journal Article
  7. 7
  8. 8

    The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in Streptomyces lividans by Seghezzi, Nicolas, Darbon, Emmanuelle, Martel, Cécile, David, Michelle, Lejeune, Clara, Esnault, Catherine, Virolle, Marie-Joelle

    Published in Antibiotics (Basel) (27-08-2022)
    “…In most Streptomyces species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low…”
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    Journal Article
  9. 9

    Genome Analysis of a Variant of Streptomyces coelicolor M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics by Dulermo, Thierry, Lejeune, Clara, Aybeke, Ece, Abreu, Sonia, Bleton, Jean, David, Michelle, Deniset-Besseau, Ariane, Chaminade, Pierre, Thibessard, Annabelle, Leblond, Pierre, Virolle, Marie-Joelle

    Published in Microorganisms (Basel) (31-05-2023)
    “…M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in species. This strain abundantly produces the blue…”
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    Journal Article
  10. 10

    Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain by Apel, Cécile, Levasseur, Marceau, Lejeune, Clara, Korch, Shaleen B, Guérard, Florence, David, Michelle, Askora, Ahmed, Litaudon, Marc, Roussi, Fanny, Gakière, Bertrand, Chaput, John, Virolle, Marie-Joelle

    “…ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms However,…”
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    Journal Article Publication
  11. 11

    The Phosin PptA Plays a Negative Role in the Regulation of Antibiotic Production in Streptomyces lividans by Shikura, Noriyasu, Darbon, Emmanuelle, Esnault, Catherine, Deniset-Besseau, Ariane, Xu, Delin, Lejeune, Clara, Jacquet, Eric, Nhiri, Naima, Sago, Laila, Cornu, David, Werten, Sebastiaan, Martel, Cécile, Virolle, Marie-Joelle

    Published in Antibiotics (Basel) (20-03-2021)
    “…In , antibiotic biosynthesis is triggered in phosphate limitation that is usually correlated with energetic stress. Polyphosphates constitute an important…”
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    Journal Article
  12. 12

    Negative Correlation between Lipid Content and Antibiotic Activity in Streptomyces : General Rule and Exceptions by David, Michelle, Lejeune, Clara, Abreu, Sonia, Thibessard, Annabelle, Leblond, Pierre, Chaminade, Pierre, Virolle, Marie-Joelle

    Published in Antibiotics (Basel) (26-05-2020)
    “…Streptomycetes are well known antibiotic producers and are among the rare prokaryotes able to store carbon as lipids. Previous comparative studies of the weak…”
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    Journal Article
  13. 13

    The stringent response is strongly activated in the antibiotic producing strain, Streptomyces coelicolor by Lejeune, Clara, Cornu, David, Sago, Laila, Redeker, Virginie, Virolle, Marie-Joelle

    Published in Research in microbiology (01-05-2024)
    “…S. lividans and S. coelicolor are phylogenetically closely related strains with different abilities to produce the same specialized metabolites. Previous…”
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    Journal Article
  14. 14

    The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in IStreptomyces lividans/I by Seghezzi, Nicolas, Darbon, Emmanuelle, Martel, Cécile, David, Michelle, Lejeune, Clara, Esnault, Catherine, Virolle, Marie-Joelle

    Published in Antibiotics (Basel) (01-08-2022)
    “…In most Streptomyces species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low…”
    Get full text
    Journal Article
  15. 15

    Genome Analysis of a Variant of IStreptomyces coelicolor/I M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics by Dulermo, Thierry, Lejeune, Clara, Aybeke, Ece, Abreu, Sonia, Bleton, Jean, David, Michelle, Deniset-Besseau, Ariane, Chaminade, Pierre, Thibessard, Annabelle, Leblond, Pierre, Virolle, Marie-Joelle

    Published in Microorganisms (Basel) (01-05-2023)
    “…Streptomyces coelicolor M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in Streptomyces species. This strain…”
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    Journal Article
  16. 16

    Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain by Apel, Cécile, Levasseur, Marceau, Lejeune, Clara, Korch, Shaleen B, Guérard, Florence, David, Michelle, Askora, Ahmed, Litaudon, Marc, Roussi, Fanny, Gakière, Bertrand, Chaput, John, Virolle, Marie-Joelle

    “…ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms . However,…”
    Get full text
    Journal Article
  17. 17

    "The story of Tom Thumb" by Lejeune, Clara

    Published in The Human life review (01-01-2002)
    “…The author's father and another professor discovered the cause of trisomy 21 and invented the technique of prenatal diagnosis. They would become helpless…”
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    Magazine Article
  18. 18