Search Results - "Lejeune, Clara"
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Comparative Proteomic Analysis of Transcriptional and Regulatory Proteins Abundances in S. lividans and S. coelicolor Suggests a Link between Various Stresses and Antibiotic Production
Published in International journal of molecular sciences (26-11-2022)“…and constitute model strains to study the regulation of antibiotics biosynthesis in species since these closely related strains possess the same pathways…”
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2
Expression of genes of the Pho regulon is altered in Streptomyces coelicolor
Published in Scientific reports (22-05-2020)“…Most currently used antibiotics originate from Streptomycetes and phosphate limitation is an important trigger of their biosynthesis. Understanding the…”
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3
A Proteomic Analysis Indicates That Oxidative Stress Is the Common Feature Triggering Antibiotic Production in Streptomyces coelicolor and in the pptA Mutant of Streptomyces lividans
Published in Frontiers in microbiology (22-03-2022)“…In most species, antibiotic production is triggered in phosphate limitation and repressed in phosphate proficiency. However, the model strain, , escapes this…”
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Impact of Phosphate Availability on Membrane Lipid Content of the Model Strains, Streptomyces lividans and Streptomyces coelicolor
Published in Frontiers in microbiology (22-02-2021)“…In this issue we demonstrated that the phospholipid content of varies greatly with Pi availability being was much lower in Pi limitation than in Pi proficiency…”
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Impact of the Deletion of Genes of the Nitrogen Metabolism on Triacylglycerol, Cardiolipin and Actinorhodin Biosynthesis in Streptomyces coelicolor
Published in Microorganisms (Basel) (30-07-2024)“…Since nitrogen limitation is known to be an important trigger of triacylglycerol (TAG) accumulation in most microorganisms, we first assessed the global lipid…”
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Consequences of the deletion of the major specialized metabolite biosynthetic pathways of Streptomyces coelicolor on the metabolome and lipidome of this strain
Published in Microbial biotechnology (01-08-2024)“…Chassis strains, derived from Streptomyces coelicolor M145, deleted for one or more of its four main specialized metabolites biosynthetic pathways (CPK, CDA,…”
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The Inhibition of Antibiotic Production in Streptomyces coelicolor Over-Expressing the TetR Regulator SCO3201 IS Correlated With Changes in the Lipidome of the Strain
Published in Frontiers in microbiology (23-06-2020)“…In condition of over-expression, SCO3201, a regulator of the TetR family was previously shown to strongly inhibit antibiotic production and morphological…”
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The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in Streptomyces lividans
Published in Antibiotics (Basel) (27-08-2022)“…In most Streptomyces species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low…”
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9
Genome Analysis of a Variant of Streptomyces coelicolor M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics
Published in Microorganisms (Basel) (31-05-2023)“…M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in species. This strain abundantly produces the blue…”
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Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain
Published in Frontiers in Cell and Developmental Biology (08-03-2023)“…ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms However,…”
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11
The Phosin PptA Plays a Negative Role in the Regulation of Antibiotic Production in Streptomyces lividans
Published in Antibiotics (Basel) (20-03-2021)“…In , antibiotic biosynthesis is triggered in phosphate limitation that is usually correlated with energetic stress. Polyphosphates constitute an important…”
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Negative Correlation between Lipid Content and Antibiotic Activity in Streptomyces : General Rule and Exceptions
Published in Antibiotics (Basel) (26-05-2020)“…Streptomycetes are well known antibiotic producers and are among the rare prokaryotes able to store carbon as lipids. Previous comparative studies of the weak…”
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The stringent response is strongly activated in the antibiotic producing strain, Streptomyces coelicolor
Published in Research in microbiology (01-05-2024)“…S. lividans and S. coelicolor are phylogenetically closely related strains with different abilities to produce the same specialized metabolites. Previous…”
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The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in IStreptomyces lividans/I
Published in Antibiotics (Basel) (01-08-2022)“…In most Streptomyces species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low…”
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Genome Analysis of a Variant of IStreptomyces coelicolor/I M145 with High Lipid Content and Poor Ability to Synthetize Antibiotics
Published in Microorganisms (Basel) (01-05-2023)“…Streptomyces coelicolor M145 is a model strain extensively studied to elucidate the regulation of antibiotic biosynthesis in Streptomyces species. This strain…”
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16
Metabolic adjustments in response to ATP spilling by the small DX protein in a Streptomyces strain
Published in Frontiers in cell and developmental biology (08-03-2023)“…ATP wasting is recognized as an efficient strategy to enhance metabolic activity and productivity of specific metabolites in several microorganisms . However,…”
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17
"The story of Tom Thumb"
Published in The Human life review (01-01-2002)“…The author's father and another professor discovered the cause of trisomy 21 and invented the technique of prenatal diagnosis. They would become helpless…”
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Magazine Article -
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LE MARIAGE: NORME SOCIALE OU PASSION AMOUREUSE?
Published in Revue des deux mondes (1982) (01-11-1999)Get full text
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