Search Results - "Leiva, Tatiana"

Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence by Romeo-Guitart, David, Forés, Joaquim, Herrando-Grabulosa, Mireia, Valls, Raquel, Leiva-Rodríguez, Tatiana, Galea, Elena, González-Pérez, Francisco, Navarro, Xavier, Petegnief, Valerie, Bosch, Assumpció, Coma, Mireia, Mas, José Manuel, Casas, Caty

“…Here we used a systems biology approach and artificial intelligence to identify a neuroprotective agent for the treatment of peripheral nerve root avulsion…”
Get full text

Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1G93A ALS mice and after partial muscle denervation by Mancuso, Renzo, Martínez-Muriana, Anna, Leiva, Tatiana, Gregorio, David, Ariza, Lorena, Morell, Marta, Esteban-Pérez, Jesús, García-Redondo, Alberto, Calvo, Ana C, Atencia-Cibreiro, Gabriela, Corfas, Gabriel, Osta, Rosario, Bosch, Assumpció, Navarro, Xavier

“…Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of motoneurons, which is preceded by loss…”
Get full text

ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons by Leiva-Rodríguez, Tatiana, Romeo-Guitart, David, Marmolejo-Martínez-Artesero, Sara, Herrando-Grabulosa, Mireia, Bosch, Assumpció, Forés, Joaquim, Casas, Caty

“…Injured neurons should engage endogenous mechanisms of self-protection to limit neurodegeneration. Enhancing efficacy of these mechanisms or correcting…”
Get full text

GRP78 Overexpression Triggers PINK1-IP3R-Mediated Neuroprotective Mitophagy by Leiva-Rodríguez, Tatiana, Romeo-Guitart, David, Herrando-Grabulosa, Mireia, Muñoz-Guardiola, Pau, Polo, Miriam, Bañuls, Celia, Petegnief, Valerie, Bosch, Assumpció, Lizcano, Jose Miguel, Apostolova, Nadezda, Forés, Joaquim, Casas, Caty

“…An experimental model of spinal root avulsion (RA) is useful to study causal molecular programs that drive retrograde neurodegeneration after neuron-target…”
Get full text

Improved Motor Nerve Regeneration by SIRT1/Hif1a-Mediated Autophagy by Romeo-Guitart, David, Leiva-Rodriguez, Tatiana, Forés, Joaquim, Casas, Caty

“…Complete restoring of functional connectivity between neurons or target tissue after traumatic lesions is still an unmet medical need. Using models of nerve…”
Get full text

SIRT2 Inhibition Improves Functional Motor Recovery After Peripheral Nerve Injury by Romeo-Guitart, David, Leiva-Rodríguez, Tatiana, Casas, Caty

“…Sirtuin-2 (Sirt2) is a member of the NAD (+)-dependent protein deacetylase family involved in neuroprotection, cellular metabolism, homeostasis, and stress…”
Get full text

SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons by Romeo-Guitart, David, Leiva-Rodríguez, Tatiana, Espinosa-Alcantud, María, Sima, Núria, Vaquero, Alejandro, Domínguez- Martín, Helena, Ruano, Diego, Casas, Caty

“…Sirtuin 1 (SIRT1) activity is neuroprotective, and we have recently demonstrated its role in the retrograde degenerative process in motoneurons (MNs) in the…”
Get full text

Enfermedad de Graves en el embarazo: un enfoque en el manejo y complicaciones asociadas by Piedra Ugarte, Kristel, Leiva Segura, Tatiana Yazmín, Mora Garro, Rosa Angélica

“…La enfermedad de Graves representa la principal causa de hipertiroidismo durante el embarazo. Aunque su prevalencia es baja, resulta esencial su manejo precoz…”
Get full text

Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1(G93A) ALS mice and after partial muscle denervation by Mancuso, Renzo, Martínez-Muriana, Anna, Leiva, Tatiana, Gregorio, David, Ariza, Lorena, Morell, Marta, Esteban-Pérez, Jesús, García-Redondo, Alberto, Calvo, Ana C, Atencia-Cibreiro, Gabriela, Corfas, Gabriel, Osta, Rosario, Bosch, Assumpció, Navarro, Xavier

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of motoneurons, which is preceded by loss of…”
Get full text