Search Results - "Leitner, William P"
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The Alzheimer's Aβ-Peptide Is Deposited at Sites of Complement Activation in Pathologic Deposits Associated with Aging and Age-Related Macular Degeneration
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2002)“…Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in older individuals worldwide. The disease is characterized by abnormal…”
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Journal Article -
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Complement Activation and Inflammatory Processes in Drusen Formation and Age Related Macular Degeneration
Published in Experimental eye research (01-12-2001)“…Recent studies implicate inflammation and complement mediated attack as early events in drusen biogenesis. The investigations described here sought to…”
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Journal Article -
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Glial Remodeling and Neural Plasticity in Human Retinal Detachment with Proliferative Vitreoretinopathy
Published in Investigative ophthalmology & visual science (01-01-2005)“…To investigate glial remodeling and neuronal plasticity in adult human retinal detachment complicated by proliferative vitreoretinopathy (PVR) and to grade…”
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Journal Article -
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The Ability of Rapid Retinal Reattachment to Stop or Reverse the Cellular and Molecular Events Initiated by Detachment
Published in Investigative ophthalmology & visual science (01-07-2002)“…To determine the effects of reattachment on the molecular and cellular events initiated by a retinal detachment lasting 1 hour or 1 day. Experimental retinal…”
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Journal Article -
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FDA Influence on Advisory Committees Through Documentation: A Content Analysis and Survey of Industry Views
Published 01-01-2015“…The primary role of an FDA advisory committee is to provide independent, expert scientific advice to support FDA’s evaluation of specific drugs, biologics, or…”
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Dissertation -
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The Alzheimer's Abeta-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2002)“…Age-related macular degeneration (AMD) is characterized by abnormal extracellular deposits, known as drusen, that accumulate along the basal surface of the…”
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Journal Article