Search Results - "Leiter, J. C."
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Amperometric Detection of Dopamine in Vivo with an Enzyme Based Carbon Fiber Microbiosensor
Published in Analytical chemistry (Washington) (01-02-2010)“…We developed a novel implantable enzyme-based carbon fiber biosensor for in vivo monitoring of dopamine. The biosensor is fabricated using tyrosinase…”
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Model-based analysis of the acute effects of transcutaneous magnetic spinal cord stimulation on micturition after spinal cord injury in humans
Published in PLoS computational biology (01-07-2024)“…After spinal cord injuries (SCIs), patients may develop either detrusor-sphincter dyssynergia (DSD) or urinary incontinence, depending on the level of the…”
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Glutamate oxidase biosensor based on mixed ceria and titania nanoparticles for the detection of glutamate in hypoxic environments
Published in Biosensors & bioelectronics (15-02-2014)“…We report on the design and development of a glutamate oxidase (GmOx) microelectrode for measuring l-glutamic acid (GluA) in oxygen-depleted conditions, which…”
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Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration
Published in Scientific reports (17-02-2021)“…Motor deficits are observed in Alzheimer’s disease (AD) prior to the appearance of cognitive symptoms. To investigate the role of amyloid proteins in gait…”
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Ventilation of patients with acute lung injury and acute respiratory distress syndrome: Has new evidence changed clinical practice?
Published in Critical care medicine (01-06-2004)“…OBJECTIVES:A recent randomized trial of mechanical ventilation in acute lung injury (ALI)/adult respiratory distress syndrome (ARDS) demonstrated a 22%…”
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The Hering-Breuer reflex, feedback control, and mechanical ventilation: The promise of neurally adjusted ventilatory assist
Published in Critical care medicine (01-09-2010)Get full text
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Mechanisms of pathogenesis in the Sudden Infant Death Syndrome
Published in Respiratory physiology & neurobiology (15-11-2007)“…Abstract The likely processes of the Sudden Infant Death Syndrome (SIDS) were identified many years ago (apnea, failed arousal, failed autoresuscitation,…”
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Heart rate variability during sleep and the early development of posttraumatic stress disorder
Published in Biological psychiatry (1969) (01-05-2004)“…Noradrenergic function has been linked to posttraumatic stress disorder (PTSD) and might have a role in mediating sleep disturbances of the disorder. Our…”
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Response of membrane potential and intracellular pH to hypercapnia in neurons and astrocytes from rat retrotrapezoid nucleus
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-09-2005)“…We compared the response to hypercapnia (10%) in neurons and astrocytes among a distinct area of the retrotrapezoid nucleus (RTN), the mediocaudal RTN (mcRTN),…”
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High-frequency stimulation of the subthalamic nucleus increases glutamate in the subthalamic nucleus of rats as demonstrated by in vivo enzyme-linked glutamate sensor
Published in Brain research (08-08-2007)“…Abstract Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective therapy for Parkinson's disease; however, the mechanism whereby DBS…”
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TRPV1 channels in the nucleus of the solitary tract mediate thermal prolongation of the LCR in decerebrate piglets
Published in Respiratory physiology & neurobiology (30-04-2011)“…Abstract Elevating body temperature or just the temperature of the dorsal medulla by approximately 2 °C prolongs the laryngeal chemoreflex (LCR) in decerebrate…”
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Reproducibility of point‐of‐care ultrasonography for central vein diameter measurement: Separating image acquisition from interpretation
Published in Journal of clinical ultrasound (01-10-2017)“…ABSTRACT Purpose Central vein point‐of‐care ultrasonography must be reproducible to detect intravascular volume changes. We sought to determine which…”
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Gestational nicotine exposure exaggerates hyperthermic enhancement of laryngeal chemoreflex in rat pups
Published in Respiratory physiology & neurobiology (15-04-2010)“…Abstract Laryngeal chemoreflex (LCR) apnea occurs in infant mammals in response to water or other liquids in the laryngeal lumen and is suspected to contribute…”
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Chemosensory Responses to CO2 in Multiple Brain Stem Nuclei Determined Using a Voltage-Sensitive Dye in Brain Slices From Rats
Published in Journal of neurophysiology (01-09-2009)“…1 Department of Biology, St. Lawrence University, Canton, New York; 2 Department of Anatomy and Physiology, Wright State Medical School, Dayton, Ohio; and 3…”
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Genesis of gasping is independent of levels of serotonin in the Pet-1 knockout mouse
Published in Journal of applied physiology (1985) (01-09-2009)“…Department of Physiology, Dartmouth Medical School, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire Submitted 10 November 2008 ; accepted in final…”
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Upper airway shape: Is it important in the pathogenesis of obstructive sleep apnea?
Published in American journal of respiratory and critical care medicine (01-03-1996)“…It is widely accepted that the size of the airway and the level of upper airway muscle activity contribute to the pathogenesis of obstructive sleep apnea…”
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Persistence of eupnea and gasping following blockade of both serotonin type 1 and 2 receptors in the in situ juvenile rat preparation
Published in Journal of applied physiology (1985) (01-07-2007)“…1 Institute of Arctic Biology, University of Alaska Fairbanks, Alaska; and 2 Department of Physiology, Dartmouth Medical School, Dartmouth-Hitchcock Medical…”
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Discharge of the hypoglossal nerve cannot distinguish eupnea from gasping, as defined by phrenic discharge, in the in situ mouse
Published in Journal of applied physiology (1985) (01-09-2009)“…Department of Physiology, Dartmouth Medical School, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire Submitted 12 January 2009 ; accepted in final…”
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A Proof-of-Concept Study of Transcutaneous Magnetic Spinal Cord Stimulation for Neurogenic Bladder
Published in Scientific reports (22-08-2018)“…Patients with chronic spinal cord injury (SCI) cannot urinate at will and must empty the bladder by self-catheterization. We tested the hypothesis that…”
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