Search Results - "Leite, L.C.C"

Recombinant vaccines and the development of new vaccine strategies by Nascimento, I P, Leite, L C C

“…Vaccines were initially developed on an empirical basis, relying mostly on attenuation or inactivation of pathogens. Advances in immunology, molecular biology,…”
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The long search for a serotype independent pneumococcal vaccine by Converso, T R, Assoni, L, André, G O, Darrieux, M, Leite, L C C

“…: Serotype replacement - a consequence of polysaccharide vaccine use - will continue to drive the inclusion of new serotypes on conjugate vaccines, increasing…”
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Systemic immunization with rPotD reduces Streptococcus pneumoniae nasopharyngeal colonization in mice by Converso, T.R, Goulart, C, Rodriguez, D, Darrieux, M, Leite, L.C.C

“…Abstract Streptococcus pneumoniae (pneumococcus) is a human pathogen that can cause otitis media, pneumonia and, in severe cases, meningitis and bacteremia…”
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Combined effects of lactoferrin and lysozyme on Streptococcus pneumoniae killing by André, G.O., Politano, W.R., Mirza, S., Converso, T.R., Ferraz, L.F.C., Leite, L.C.C., Darrieux, M.

“…Streptococcus pneumoniae is a common colonizer of the human nasopharynx, which can occasionally spread to sterile sites, causing diseases such as otitis media,…”
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Schistosoma mansoni: Molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages by Araujo-Montoya, B.O., Rofatto, H.K., Tararam, C.A., Farias, L.P., Oliveira, K.C., Verjovski-Almeida, S., Wilson, R.A., Leite, L.C.C.

“…[Display omitted] ► Complete molecular analysis of Schistosoma mansoni Alkaline Phosphatase cDNA gene. ► Transcriptional analysis and expression profile of…”
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Induction of IFN-γ and IL-17 by Pneumococcal Surface Protein C-Based Vaccines does not Protect Against a Streptococcus pneumoniae Invasive Challenge by Ferreira, D.M, Darrieux, M, Silva, D.A, Leite, L.C.C, Ho, P.L, Miyaji, E.N, Oliveira, M.L.S

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Recombinant vaccines and the development of new vaccine strategies by I.P. Nascimento, L.C.C. Leite

“…Vaccines were initially developed on an empirical basis, relying mostly on attenuation or inactivation of pathogens. Advances in immunology, molecular biology,…”
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A protein chimera including PspA in fusion with PotD is protective against invasive pneumococcal infection and reduces nasopharyngeal colonization in mice by Converso, T.R., Goulart, C., Darrieux, M., Leite, L.C.C.

“…Despite the success of the available polysaccharide-based vaccines against Streptococcus pneumoniae in preventing invasive diseases, this bacterium remains a…”
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Rational selection of broadly cross-reactive family 2 PspA molecules for inclusion in chimeric pneumococcal vaccines by Converso, T.R., Goulart, C., Rodriguez, D., Darrieux, M., Leite, L.C.C.

“…Pneumococcal surface protein A (PspA) is a widely studied pneumococcal protein, exposed at the surface of all strains. It is an important virulence factor,…”
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Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis by Nascimento, Ivan P., Rodriguez, Dunia, Santos, Carina C., Amaral, Eduardo P., Rofatto, Henrique K., Junqueira-Kipnis, Ana P., Gonçalves, Eduardo D. C., D’Império-Lima, Maria R., Hirata, Mario H., Silva, Celio L., Winter, Nathalie, Gicquel, Brigitte, Mills, Kingston H. G., Pizza, Mariagrazia, Rappuoli, Rino, Leite, Luciana C. C.

“…In order to develop an improved BCG vaccine against tuberculosis we have taken advantage of the adjuvant properties of a non-toxic derivative of Escherichia…”
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Fusion Proteins Containing Family 1 and Family 2 PspA Fragments Elicit Protection against Streptococcus pneumoniae That Correlates with Antibody-Mediated Enhancement of Complement Deposition by Darrieux, M, Miyaji, E.N, Ferreira, D.M, Lopes, L.M, Lopes, A.P.Y, Ren, B, Briles, D.E, Hollingshead, S.K, Leite, L.C.C

“…PspA is an important pneumococcal vaccine candidate that is capable of inducing protection in different animal models. Because of its structural diversity, a…”
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Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis by Gamberini, Marcia, Gómez, Ricardo M., Atzingen, Marina V., Martins, Elizabeth A.L., Vasconcellos, Silvio A., Romero, Eliete C., Leite, Luciana C.C., Ho, Paulo L., Nascimento, Ana L.T.O.

“…Leptospirosis is an important global human and veterinary health problem. Humans can be infected by exposure to chronically infected animals and their…”
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Intranasal Immunization with the Cholera Toxin B Subunit-Pneumococcal Surface Antigen A Fusion Protein Induces Protection against Colonization with Streptococcus pneumoniae and Has Negligible Impact on the Nasopharyngeal and Oral Microbiota of Mice by Pimenta, F.C, Miyaji, E.N, Arêas, A.P.M, Oliveira, M.L.S, de Andrade, A.L.S.S, Ho, P.L, Hollingshead, S.K, Leite, L.C.C

“…One of the candidate proteins for a mucosal vaccine antigen against Streptococcus pneumoniae is PsaA (pneumococcal surface antigen A). Vaccines targeting…”
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Purification of meningococcal group C polysaccharide by a procedure suitable for scale-up by Tanizaki, Martha M., Garcia, Ligiane R., Ramos, Julia B., Leite, Luciana C.C., Hiss, Haroldo, Furuta, Joana A., Cabrera-Crespo, Joaquin, Raw, Isaias

“…Neisseria meningitidis group C capsular polysaccharide is the antigen for the vaccine. An easier method has been developed for the purification of N…”
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Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells by Bennett, S A, Leite, L C, Birnboim, H C

“…The ability of platelet activating factor (PAF), a potent endogenous inflammatory agent, to induce phenotypic transformation of primary rat embryo cells (RECs)…”
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