Search Results - "Leite, John F."

Conformation-Dependent Hydrophobic Photolabeling of the Nicotinic Receptor: Electrophysiology-Coordinated Photochemistry and Mass Spectrometry by Leite, John F., Blanton, Michael P., Shahgholi, Mona, Dougherty, Dennis A., Lester, Henry A.

“…We characterized the differential accessibility of the nicotinic acetylcholine receptor α1 subunit in the open, closed, and desensitized states by using…”
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Cys-loop receptors: new twists and turns by Lester, Henry A., Dibas, Mohammed I., Dahan, David S., Leite, John F., Dougherty, Dennis A.

“…New hypotheses and predictions have arisen from recent work revealing atomic-scale or near-atomic-scale structures of receptors in the ‘Cys-loop’ superfamily…”
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Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide by Leite, John F., Dougherty, Dennis A., Lester, Henry A., Shahgholi, Mona

“…In a previous study utilizing benzophenone‐based topological probes to study conformationally dependent changes in mouse muscle nicotinic acetylcholine…”
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Probing the Topology of the Glycine Receptor by Chemical Modification Coupled to Mass Spectrometry by Leite, John F, Cascio, Michael

“…Tetranitromethane (TNM), a small aqueous reagent that specifically modifies solvent-accessible tyrosine residues to o-nitrotyrosine, was used to probe the…”
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Coupled Proteolytic and Mass Spectrometry Studies Indicate a Novel Topology for the Glycine Receptor by Leite, John F., Amoscato, Andrew A., Cascio, Michael

“…Members of the heteropentameric ligand-gated ion channel superfamily rapidly mediate signaling across the synaptic cleft. Sequence analysis and limited…”
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Removal of sodium and potassium adducts using a matrix additive during matrix-associated laser desorption/ionization time-of-flight mass spectrometric analysis of peptides by Leite, John F., Hajivandi, Mahbod R., Diller, Thomas, Pope, R. Marshall

“…Monovalent cations often associate with peptides and proteins under mass spectrometry (MS) conditions, resulting in a discernable, but often misleading, adduct…”
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Insights into channel function via channel dysfunction by Leite, John F, Rodrigues-Pinguet, Nivalda, Lester, Henry A

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In vitro interaction of the glycine receptor with the leptin receptor by Leite, John F., Gribble, Brian, Randolph, Norman, Cascio, Michael

“…The coordination and regulation of electrical signals across excitable cells is a complex, dynamic phenomenon requiring, in part, the interaction of ion…”
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Evaluation of Patient Outcome Benefits and Resource Utilization Associated with a Hematopathologist-Directed Workflow for Diagnosis of Hematological Malignancies by Leite, John F, Sur, Sudipto, Dabbas, Bashar, Gilmore, James, Haislip, Sally, Nerenberg, Mike I.

“…Abstract 3127 Traditionally, the appropriate selection of diagnostic tests is determined solely by the ordering clinician. This can be quite challenging in the…”
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Structure of Ligand-Gated Ion Channels: Critical Assessment of Biochemical Data Supports Novel Topology by Leite, John F., Cascio, Michael

“…Rapidsignaling across the synaptic junction is partially mediated by the ligand-gated ion channel superfamily (LGICS), which includes inhibitory glycine and…”
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Insights into channel function via channel dysfunction by Leite, J. F.

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In vitro interaction of the glycine receptor with the leptin receptor: The Pittsburgh Special Issue by LEITE, John F, GRIBBLE, Brian, RANDOLPH, Norman, CASCIO, Michael

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