Search Results - "Leitao, Luciana Pereira Colares"
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Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population
Published in Scientific reports (24-06-2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common cancer in children. Differences are found among ethnic groups in the results of the treatment of…”
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The Genomic Profile Associated with Risk of Severe Forms of COVID-19 in Amazonian Native American Populations
Published in Journal of personalized medicine (01-04-2022)“…Genetic factors associated with COVID-19 disease outcomes are poorly understood. This study aimed to associate genetic variants in the , , , , , , and genes…”
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Influence of APOE locus on poor prognosis of COVID-19
Published in Heliyon (01-06-2021)“…The COVID-19 pandemic has infected over 25 million of people worldwide, 5% of whom evolved to death and, among of the active cases, more than 60 thousand are…”
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Association between the TPMT3C (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region
Published in Genes (25-09-2020)“…Acute lymphoblastic leukemia (ALL) is the leading cause of death from pediatric cancer worldwide. However, marked ethnic disparities are found in the treatment…”
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Epidemiological-molecular profile of variants associated with type 2 diabetes mellitus in indigenous populations from the Brazilian Amazon
Published in Diabetes research and clinical practice (01-05-2023)“…Aims: While lifestyle factors are strongly associated with Type 2 diabetes (T2DM), genetic characteristics also play a role. However, much of the research on…”
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Pharmacogenomics and variations in the risk of toxicity during the consolidation/maintenance phases of the treatment of pediatric B-cell leukemia patients from an admixed population in the Brazilian Amazon
Published in Leukemia research (01-11-2018)“…•During the consolidation phase, 45.5% of the patients presented at least one episode of toxicity.•During the maintenance phase, 19.8% of the patients suffered…”
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Effect of genetic ancestry to the risk of susceptibility to gastric cancer in a mixed population of the Brazilian Amazon
Published in BMC research notes (29-11-2017)“…Global literature describes differences in the incidence of gastric cancer among populations. For instance, Europeans have lower incidence rates of gastric…”
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Correction to: Effect of genetic ancestry to the risk of susceptibility to gastric cancer in a mixed population of the Brazilian Amazon
Published in BMC research notes (21-12-2017)“…Following publication of the original article [1], the authors requested a correction to the name of one of the co-authors. The correct name Marianne Rodrigues…”
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Association of genes ARID5B, CEBPE and folate pathway with acute lymphoblastic leukemia in a population from the Brazilian Amazon region
Published in Leukemia research reports (2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common childhood neoplasia. Studies have shown that susceptibility to ALL may be modulated by genetic variables…”
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Effect of American genomic ancestry on severe toxicities in children with acute lymphoblastic leukemia in the Amazon region
Published in Discover. Oncology (18-05-2024)“…Background Acute Lymphoblastic Leukemia (ALL) is a neoplasm of the hematopoietic system characterized by a clonal expansion of abnormal lymphocyte precursor…”
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Severe toxicities in amazonian populations and the role of precision medicine in acute lymphoblastic leukemia treatment
Published in Scientific reports (26-11-2024)“…Corticosteroids, such as prednisone or dexamethasone, constitute integral components of antineoplastic regimens for Acute Lymphoblastic Leukemia (ALL) therapy,…”
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Letalidade da COVID-19 entre profissionais de saúde no Pará, Brasil
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Letalidade da COVID-19 entre profissionais de saúde no Pará, Brasil
Published in Journal Health NPEPS (01-06-2021)“…Objetivo: analisar a letalidade da COVID-19 por sexo e idade entre os profissionais de saúde no Pará, Brasil. Método: estudo epidemiológico e observacional,…”
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