Search Results - "Leitão, Alvaro C."
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Photoprotection assessment of olive (Olea europaea L.) leaves extract standardized to oleuropein: In vitro and in silico approach for improved sunscreens
Published in Journal of photochemistry and photobiology. B, Biology (01-04-2019)“…Olive leaves contain higher amount of polyphenols than olive oil and represent a waste product from olive harvest and pruning of olive trees. The most abundant…”
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The anabolic androgenic steroid nandrolone decanoate disrupts redox homeostasis in liver, heart and kidney of male Wistar rats
Published in PloS one (16-09-2014)“…The abuse of anabolic androgenic steroids (AAS) may cause side effects in several tissues. Oxidative stress is linked to the pathophysiology of most of these…”
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Effect of the FE2+ chelation by 2,2′-dipyridyl in the doxorubicin-induced lethality in breast tumor cell lines
Published in Life sciences (1973) (01-01-2018)“…Breast cancer cells may exhibit changes in iron homeostasis, which results in increased labile iron pool (LIP) levels. Several studies highlight the crucial…”
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Titanium dioxide-montmorillonite nanocomposite as photoprotective agent against ultraviolet B radiation-induced mutagenesis in Saccharomyces cerevisiae: a potential candidate for safer sunscreens
Published in Journal of pharmaceutical sciences (01-08-2014)“…Photoprotective potential and biological consequences (mutagenic potential) of octyl-dimethyl-PABA (ODP), titanium dioxide (TiO2 ), and montmorillonite (MMT)…”
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Influence of Ogg1 repair on the genetic stability of ccc2 mutant of Saccharomyces cerevisiae chemically challenged with 4-nitroquinoline-1-oxide (4-NQO)
Published in Mutagenesis (01-01-2016)“…In Saccharomyces cerevisiae, disruption of genes by deletion allowed elucidation of the molecular mechanisms of a series of human diseases, such as in Wilson…”
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Genotoxic and Cytotoxic Safety Evaluation of Papain (Carica papaya L.) Using In Vitro Assays
Published in Journal of biomedicine & biotechnology (01-01-2010)“…Papain, a phytotherapeutic agent, has been used in the treatment of eschars and as a debriding chemical agent to remove damaged or necrotic tissue of pressure…”
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Insights and controversies on sunscreen safety
Published in Critical reviews in toxicology (13-09-2020)“…Although sunlight provides several benefits, ultraviolet (UV) radiation plays an important role in the development of various skin damages such as erythema,…”
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Microbiological Decontamination of Water: Improving the Solar Disinfection Technique (SODIS) with the Use of Nontoxic Vital Dye Methylene Blue
Published in Photochemistry and photobiology (01-03-2019)“…Rational use of water is a major challenge for governments and global organizations, with easy and inexpensive interventions being sought by communities that…”
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Saccharomyces cerevisiae strains as bioindicators for titanium dioxide sunscreen photoprotective and photomutagenic assessment
Published in Journal of photochemistry and photobiology. B, Biology (01-09-2019)“…Although several short-term assays are available for cosmetic photosafety assessment, cell models are usually highly sensitive to UV radiation, tending to…”
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Repair of DNA Lesions Induced by Hydrogen Peroxide in the Presence of Iron Chelators in Escherichia coli: Participation of Endonuclease IV and Fpg
Published in Journal of Bacteriology (01-04-2000)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Interaction of stannous chloride leads to alteration in DNA, triphosphate nucleotides and isolated bases
Published in Molecular and cellular biochemistry (01-12-2005)“…Stannous chloride (SnCl2) is a reducing chemical agent used in several man-made products. SnCl2 can generate reactive oxygen species (ROS); therefore, studies…”
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Insight from the draft genome of Dietzia cinnamea P4 reveals mechanisms of survival in complex tropical soil habitats and biotechnology potential
Published in Antonie van Leeuwenhoek (01-02-2012)“…The draft genome of Dietzia cinnamea strain P4 was determined using pyrosequencing. In total, 428 supercontigs were obtained and analyzed. We here describe and…”
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Nuclear and mitochondrial genome instability induced by fractions of ethanolic extract from Hovenia dulcis Thunberg in Saccharomyces cerevisiae strains
Published in Anais da Academia Brasileira de Ciências (01-01-2021)“…Abstract Hovenia dulcis is a plant commonly used as a pharmaceutical supplement, having displayed important pharmacological properties such antigiardic,…”
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Cytotoxicity of Extracts from Petiveria alliacea Leaves on Yeast
Published in Plants (Basel) (27-11-2022)“…L. is a plant used in traditional medicine harboring pharmacological properties with anti-inflammatory, antinociceptive, hypoglycemiant and anesthetic…”
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Reevaluating the role of 1,10-phenanthroline in oxidative reactions involving ferrous ions and DNA damage
Published in Biochimica et biophysica acta (18-11-2004)“…It is widely believed that the iron chelator 1,10-phenanthroline (phen) is able to fully block the Fenton reaction by forming a complex (Fe(phen) 3 2+, also…”
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Enhanced Sensitivity of Escherichia coli uvr B Mutants to Mitomycin C Points to a UV-C Distinct Repair for DNA Adducts
Published in Chemical research in toxicology (16-10-2006)Get full text
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Differential survival of Escherichia coli uvrA, uvrB, and uvrC mutants to psoralen plus UV-A (PUVA): Evidence for uncoupled action of nucleotide excision repair to process DNA adducts
Published in Journal of photochemistry and photobiology. B, Biology (21-01-2010)“…The nucleotide excision repair mechanism (NER) of Escherichia coli is responsible for the recognition and elimination of more than twenty different DNA…”
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Enhanced Sensitivity of Escherichia coli uvrB Mutants to Mitomycin C Points to a UV-C Distinct Repair for DNA Adducts
Published in Chemical research in toxicology (16-10-2006)“…Nucleotide excision repair (NER) in Escherichia coli repairs DNA by incising the damaged strand on the 3‘ and 5‘ sides of the lesion within pyrimidine dimers…”
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Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts
Published in Genetics and molecular biology (01-01-2010)“…Echinodorus macrophyllus, commonly known as chapéu-de-couro, is a medicinal plant used in folk medicine to treat inflammation and rheumatic diseases. In this…”
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Comparative studies of phenotypic and genetic characteristics between two desulfurizing isolates of Rhodococcus erythropolis and the well-characterized R. erythropolis strain IGTS8
Published in Journal of industrial microbiology & biotechnology (01-06-2007)“…Two Rhodococcus erythropolis isolates, named A66 and A69, together with the well-characterized R. erythropolis strain IGTS8 were compared biochemically and…”
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