Search Results - "Leipold, Friedemann"

A reductive aminase from Aspergillus oryzae by Aleku, Godwin A., France, Scott P., Man, Henry, Mangas-Sanchez, Juan, Montgomery, Sarah L., Sharma, Mahima, Leipold, Friedemann, Hussain, Shahed, Grogan, Gideon, Turner, Nicholas J.

“…Reductive amination is one of the most important methods for the synthesis of chiral amines. Here we report the discovery of an NADP(H)-dependent reductive…”
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Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole-Cell Biocatalyst Containing an (S)-Imine Reductase by Leipold, Friedemann, Hussain, Shahed, Ghislieri, Diego, Turner, Nicholas J.

“…Biocatalytic imine reduction: A whole‐cell recombinant E. coli system, producing an (S)‐selective imine reductase (IRED) from Streptomyces sp. GF3546, is…”
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Stereoselectivity and Structural Characterization of an Imine Reductase (IRED) from Amycolatopsis orientalis by Aleku, Godwin A, Man, Henry, France, Scott P, Leipold, Friedemann, Hussain, Shahed, Toca-Gonzalez, Laura, Marchington, Rebecca, Hart, Sam, Turkenburg, Johan P, Grogan, Gideon, Turner, Nicholas J

“…The imine reductase AoIRED from Amycolatopsis orientalis (Uniprot R4SNK4) catalyzes the NADPH-dependent reduction of a wide range of prochiral imines and…”
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Mapping the substrate scope of monoamine oxidase (MAO-N) as a synthetic tool for the enantioselective synthesis of chiral amines by Herter, Susanne, Medina, Florian, Wagschal, Simon, Benhaïm, Cyril, Leipold, Friedemann, Turner, Nicholas J.

“…[Display omitted] A library of 132 racemic chiral amines (α-substituted methylbenzylamines, benzhydrylamines, 1,2,3,4-tetrahydronaphthylamines (THNs),…”
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An (R)-Imine Reductase Biocatalyst for the Asymmetric Reduction of Cyclic Imines by Hussain, Shahed, Leipold, Friedemann, Man, Henry, Wells, Elizabeth, France, Scott P., Mulholland, Keith R., Grogan, Gideon, Turner, Nicholas J.

“…Although the range of biocatalysts available for the synthesis of enantiomerically pure chiral amines continues to expand, few existing methods provide access…”
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Enzyme Toolbox: Novel Enantiocomplementary Imine Reductases by Scheller, Philipp N., Fademrecht, Silvia, Hofelzer, Sebastian, Pleiss, Jürgen, Leipold, Friedemann, Turner, Nicholas J., Nestl, Bettina M., Hauer, Bernhard

“…Reducing reactions are among the most useful transformations for the generation of chiral compounds in the fine‐chemical industry. Because of their exquisite…”
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Chemo-Enzymatic Depolymerization of Functionalized Low-Molecular-Weight Polyethylene by Bornscheuer, Uwe, Oiffer, Thomas, Leipold, Friedemann, Süss, Philipp, Breite, Daniel, Griebel, Jan, Khurram, Muhammad, Branson, Yannick, de Vries, Erik, Schulze, Agnes, Helm, Christiane A, Wei, Ren

“…Polyethylene (PE) is the most commonly used plastic type in the world, contributing significantly to the plastic waste crisis. Microbial degradation of PE in…”
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Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline by Man, Henry, Wells, Elizabeth, Hussain, Shahed, Leipold, Friedemann, Hart, Sam, Turkenburg, Johan P., Turner, Nicholas J., Grogan, Gideon

“…Oxidoreductases from Streptomyces sp. GF3546 [3546‐IRED], Bacillus cereus BAG3X2 (BcIRED) and Nocardiopsis halophila (NhIRED) each reduce prochiral…”
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Cloning, expression and characterization of a eukaryotic cycloalkanone monooxygenase from Cylindrocarpon radicicola ATCC 11011 by Leipold, Friedemann, Wardenga, Rainer, Bornscheuer, Uwe T.

“…In this study, we have cloned and characterized a cycloalkanone monooxygenase (CAMO) from the ascomycete Cylindrocarpon radicicola ATCC 11011 (identical to…”
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Structure and Activity of NADPH-Dependent Reductase Q1EQE0 from Streptomyces kanamyceticus, which Catalyses the R-Selective Reduction of an Imine Substrate by Rodríguez-Mata, María, Frank, Annika, Wells, Elizabeth, Leipold, Friedemann, Turner, Nicholas J., Hart, Sam, Turkenburg, Johan P., Grogan, Gideon

“…NADPH‐dependent oxidoreductase Q1EQE0 from Streptomyces kanamyceticus catalyzes the asymmetric reduction of the prochiral monocyclic imine 2‐methyl‐1‐pyrroline…”
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The steroid monooxygenase from Rhodococcus rhodochrous; a versatile biocatalyst by Leipold, Friedemann, Rudroff, Florian, Mihovilovic, Marko D., Bornscheuer, Uwe T.

“…The substrate scope of a steroid monooxygenase (STMO) from Rhodococcus rhodochrous DSM 43269 was investigated for a large range of different ketone substrates…”
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Inside Cover: Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole-Cell Biocatalyst Containing an (S)-Imine Reductase (ChemCatChem 12/2013) by Leipold, Friedemann, Hussain, Shahed, Ghislieri, Diego, Turner, Nicholas J.

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Chemo‐Enzymatische Depolymerisation von funktionalisiertem niedermolekularem Polyethylen by Oiffer, Thomas, Leipold, Friedemann, Süss, Philipp, Breite, Daniel, Griebel, Jan, Khurram, Muhammad, Branson, Yannick, de Vries, Erik, Schulze, Agnes, Helm, Christiane A., Wei, Ren, Bornscheuer, Uwe T.

“…Abstract Polyethylen (PE) ist der weltweit am häufigsten verwendete Kunststoff und trägt erheblich zur Kunststoffabfallkrise bei. Ein mikrobieller Abbau von PE…”
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