Search Results - "Leinonen, V"

A comparative study of clinical trial and real-world data in patients with diabetic kidney disease by Kurki, Samu, Halla-aho, Viivi, Haussmann, Manuel, Lähdesmäki, Harri, Leinonen, Jussi V., Koskinen, Miika

“…A growing body of research is focusing on real-world data (RWD) to supplement or replace randomized controlled trials (RCTs). However, due to the disparities…”
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Unfolding the outcomes of surgical treatment of lumbar spinal stenosis—a prospective 5- and 10-year follow-up study by Tuomainen, I., Aalto, T, Pesonen, J., Rade, M., Pakarinen, M., Leinonen, V., Kröger, H., Airaksinen, O.

“…Purpose In this prospective study, we aim to determine surgical outcomes in patients with lumbar spinal stenosis (LSS) 10 years after surgery. Methods The…”
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Utilization of anonymization techniques to create an external control arm for clinical trial data by Mehtälä, Juha, Ali, Mehreen, Miettinen, Timo, Partanen, Liisa, Laapas, Kaisa, Niemelä, Petri T, Khorlo, Igor, Ström, Sanna, Kurki, Samu, Vapalahti, Jarno, Abdelgawwad, Khaled, Leinonen, Jussi V

“…Abstract Background Subject-level real-world data (RWD) collected during daily healthcare practices are increasingly used in medical research to assess…”
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CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings by SEPPÄLÄ, T. T, NERG, O, JÄÄSKELÄINEN, J. E, RINNE, J, SOININEN, H, LEINONEN, V, HERUKKA, S.-K, KOIVISTO, A. M, RUMMUKAINEN, J, PULI, L, ZETTERBERG, H, PYYKKÖ, O. T, HELISALMI, S, ALAFUZOFF, I, HILTUNEN, M

“…To assess the relationship between Alzheimer disease (AD)-related pathologic changes in frontal cortical brain biopsy and AD biomarkers in ventricular vs…”
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The Kuopio idiopathic normal pressure hydrocephalus protocol: initial outcome of 175 patients by Junkkari, A, Luikku, A J, Danner, N, Jyrkkänen, H K, Rauramaa, T, Korhonen, V E, Koivisto, A M, Nerg, O, Kojoukhova, M, Huttunen, T J, Jääskeläinen, J E, Leinonen, V

“…The Kuopio University Hospital (KUH) idiopathic normal pressure hydrocephalus (iNPH) cerebrospinal fluid (CSF) shunting protocol is described together with the…”
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Structural and Functional Support by Left Atrial Appendage Transplant to the Left Ventricle after a Myocardial Infarction by Leinonen, Jussi V, Leinikka, Päivi, Tarkia, Miikka, Lampinen, Milla, Emanuelov, Avishag K, Beeri, Ronen, Kankuri, Esko, Mervaala, Eero

“…The left atrial appendage (LAA) of the adult heart has been shown to contain cardiac and myeloid progenitor cells. The resident myeloid progenitor population…”
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Protein tyrosine phosphatase receptor type Q in cerebrospinal fluid reflects ependymal cell dysfunction and is a potential biomarker for adult chronic hydrocephalus by Nakajima, M., Rauramaa, T., Mäkinen, P. M., Hiltunen, M., Herukka, S.‐K., Kokki, M., Musialowicz, T., Jyrkkänen, H.‐K., Danner, N., Junkkari, A., Koivisto, A. M., Jääskeläinen, J. E., Miyajima, M., Ogino, I., Furuta, A., Akiba, C., Kawamura, K., Kamohara, C., Sugano, H., Tange, Y., Karagiozov, K., Leinonen, V., Arai, H.

“…Background and purpose Protein tyrosine phosphatase receptor type Q (PTPRQ) was extracted from the cerebrospinal fluid (CSF) of patients with probable…”
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5-Year health-related quality of life outcome in patients with idiopathic normal pressure hydrocephalus by Junkkari, A., Sintonen, H., Danner, N., Jyrkkänen, H. K., Rauramaa, T., Luikku, A. J., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Jääskeläinen, J. E., Leinonen, V.

“…Background Health-related quality of life (HRQoL) is severely impaired in persons with idiopathic normal pressure hydrocephalus (iNPH). The HRQoL improves in a…”
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Health‐related quality‐of‐life outcome in patients with idiopathic normal‐pressure hydrocephalus – a 1‐year follow‐up study by Junkkari, A., Häyrinen, A., Rauramaa, T., Sintonen, H., Nerg, O., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Luikku, A., Jääskeläinen, J. E., Leinonen, V.

“…Background and purpose This prospective study explored the factors affecting the health‐related quality‐of‐life (HRQoL) outcome in patients with idiopathic…”
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Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case by Korhonen, V E, Solje, E, Suhonen, N M, Rauramaa, T, Vanninen, R, Remes, A M, Leinonen, V

“…Behavioural variant frontotemporal dementia (bvFTD) and idiopathic normal pressure hydrocephalus (iNPH) are neurodegenerative diseases that can present with…”
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Real-world emissions of nanoparticles, particulate mass and black carbon from a plug-in hybrid vehicle compared to conventional gasoline vehicles by Karjalainen, P., Leinonen, V., Olin, M., Vesisenaho, K., Marjanen, P., Järvinen, A., Simonen, P., Markkula, L., Kuuluvainen, H., Keskinen, J., Mikkonen, S.

“…Among various Hybrid Electric Vehicles (HEVs), Plug-in Hybrid Electric Vehicles (PHEVs) charged from the grid are seen as the most advanced ones, as they can…”
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Post-mortem findings in 10 patients with presumed normal-pressure hydrocephalus and review of the literature by Leinonen, V., Koivisto, A. M., Savolainen, S., Rummukainen, J., Sutela, A., Vanninen, R., Jääskeläinen, J. E., Soininen, H., Alafuzoff, I.

“…V. Leinonen, A. M. Koivisto, S. Savolainen, J. Rummukainen, A. Sutela, R. Vanninen, J. E. Jääskeläinen, H. Soininen and I. Alafuzoff (2012) Neuropathology and…”
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Health-related quality of life in patients with idiopathic normal pressure hydrocephalus by Junkkari, A., Sintonen, H., Nerg, O., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Jääskeläinen, J. E., Leinonen, V.

“…Background and purpose Factors affecting health‐related quality of life (HRQoL) were explored in patients with idiopathic normal pressure hydrocephalus (iNPH)…”
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Left atrial appendages from adult hearts contain a reservoir of diverse cardiac progenitor cells by Leinonen, Jussi V, Emanuelov, Avishag K, Platt, Yardanna, Helman, Yaron, Feinberg, Yael, Lotan, Chaim, Beeri, Ronen

“…There is strong evidence supporting the claim that endogenous cardiac progenitor cells (CPCs) are key players in cardiac regeneration, but the anatomic source…”
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The risk and time trends for reoperations after surgery for degenerative cervical spine disease between 1999 and 2015 in Finland by Kotkansalo, A., Leinonen, V., Korajoki, M., Korhonen, K., Rinne, J., Malmivaara, A.

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Positron emission tomography with [18F]flutemetamol and [11C]PiB for in vivo detection of cerebral cortical amyloid in normal pressure hydrocephalus patients by Leinonen, V., Rinne, J. O., Virtanen, K. A., Eskola, O., Rummukainen, J., Huttunen, J., von und zu Fraunberg, M., Nerg, O., Koivisto, A. M., Rinne, J., Jääskeläinen, J. E., Buckley, C., Smith, A., Jones, P. A., Sherwin, P., Farrar, G., McLain, R., Kailajärvi, M., Heurling, K., Grachev, I. D.

“…Background and purpose This study determined the correlation between uptake of the amyloid positron emission tomography (PET) imaging agent [18F]flutemetamol…”
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Efficacy of movement control exercise versus general exercise on recurrent sub-acute low back pain: a randomized controlled trial by Lehtola, V, Luomajoki, H, Leinonen, V, Gibbons, S, Airaksinen, O

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Preoperative Predictors for Good Postoperative Satisfaction and Functional Outcome in Lumbar Spinal Stenosis Surgery — A Prospective Observational Study with a Two-Year Follow-up by Aalto, T., Sinikallio, S., Kröger, H., Viinamäki, H., Herno, A., Leinonen, V., Turunen, V., Savolainen, S., Airaksinen, O.

“…Background and Aims: Lumbar spinal stenosis (LSS) is the most frequent indication for back surgery in adults aged over 65 years, but about one-third of…”
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Successful Curriculum Change in Health Management and Leadership Studies for the Specialist Training Programs in Medicine in Finland by Parviainen, Heli M, Halava, Heli, Leinonen, Esa V J, Kosunen, Elise, Rannisto, Pasi-Heikki

“…In Finland, the specialization programs in Medicine and Dentistry can be undertaken at all five university medical faculties in 50 specialization programs and…”
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Disc herniation-related back pain impairs feed-forward control of paraspinal muscles by Leinonen, V, Kankaanpää, M, Luukkonen, M, Hänninen, O, Airaksinen, O, Taimela, S

“…A comparative study of lumbar paraspinal muscle reflexes during sudden upper limb loading in healthy control subjects and patients with sciatica. To assess…”
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