Search Results - "Leighton, J.K."
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Qualification of cardiac troponins for nonclinical use: A regulatory perspective
Published in Regulatory toxicology and pharmacology (01-10-2013)“…•Discussion of first successful use of published research for biomarker qualification.•The cardiac troponins submission and proposed context of use are…”
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Fasting decreases apolipoprotein B mRNA editing and the secretion of small molecular weight apoB by rat hepatocytes: evidence that the total amount of apoB secreted is regulated post-transcriptionally
Published in Journal of lipid research (01-09-1990)“…Two different molecular weight forms of apoB are produced from a common initial transcript via editing of a Gln codon (CAA) to a stop codon (UAA), leading to a…”
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Steroidogenic cytochrome P450 enzyme messenger ribonucleic acids and follicular fluid steroids in individual follicles during preovulatory maturation in the pig
Published in Biology of reproduction (01-09-1994)“…Changes in follicular concentrations of steroidogenic cytochrome P450 enzyme mRNAs were determined during preovulatory maturation. RNA was isolated from 59…”
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Nucleotide sequence of the rat low density lipoprotein receptor cDNA
Published in Nucleic acids research (11-02-1989)“…A 4.7 kb cDNA clone ( lambda rLDL2-1a) coding for the rat low density lipoprotein (LDL) receptor was isolated from a lambda gt-11 rat liver cDNA library. The…”
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Increased Translatable mRNA and Decreased Lipogenesis Are Responsible for the Augmented Secretion of Lipid-deficient Apolipoprotein E by Hepatocytes from Fasted Rats
Published in The Journal of biological chemistry (25-05-1989)“…We examined the mechanism through which fasting selectively increases the secretion of apoE while it decreases the secretion of all lipoprotein lipids (Davis,…”
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