Search Results - "Leighton, H. Jeff"

Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgesics by Feldman, Paul L, James, Michael K, Brackeen, Marcus F, Bilotta, Joanne M, Schuster, Suzanne V, Lahey, Avis P, Lutz, Michael W, Johnson, M. Ross, Leighton, H. Jeff

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Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics by FELDMAN, P. L, JAMES, M. K, BRACKEEN, M. F, BILOTTA, J. M, SCHUSTER, S. V, LAHEY, A. P, LUTZ, M. W, JOHNSON, M. R, LEIGHTON, H. J

“…In an effort to discover a potent ultrashort-acting mu opioid analgetic that is capable of metabolizing to an inactive species independent of hepatic function,…”
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Analysis of bradykinin-induced relaxations in the rat isolated anococcygeus muscle by Mudumbi, R V, Leighton, H J

“…The present study investigates the mechanism(s) of action of relaxations induced by bradykinin and by electrical field stimulation (EFS) in isolated rat…”
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Effects of omega-conotoxin GVIA on electrical field stimulation- and agonist-induced changes in cytosolic Ca2+ and tension in isolated rat anococcygeus muscle by Mudumbi, R V, Leighton, H J

“…1. It has been reported that omega-conotoxin GVIA (omega-CgTx) blocks L- and N-type voltage-sensitive Ca2+ channels (VSCCs) in neurones and inhibits…”
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Interaction between neurotransmitters and exogenous norepinephrine in isolated rat anococcygeus muscle by Mudumbi, Ramagopal V., Parmeter, Lonnie L., McIntyre, Margaret S., Leighton, H.Jeff

“…Continuous electrical field stimulation (EFS) elicited a sustained contraction and significantly increased the EC 50 value of norepinephrine (NE), shifting the…”
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