Search Results - "Leichner, Theresa M."

Intracellular Signals Mediating the Food Intake-Suppressive Effects of Hindbrain Glucagon-like Peptide-1 Receptor Activation by Hayes, Matthew R., Leichner, Theresa M., Zhao, Shiru, Lee, Grace S., Chowansky, Amy, Zimmer, Derek, De Jonghe, Bart C., Kanoski, Scott E., Grill, Harvey J., Bence, Kendra K.

“…Glucagon-like peptide-1 receptor (GLP-1R) activation within the nucleus tractus solitarius (NTS) suppresses food intake and body weight (BW), but the…”
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Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation by Hayes, Matthew R., Skibicka, Karolina P., Leichner, Theresa M., Guarnieri, Douglas J., DiLeone, Ralph J., Bence, Kendra K., Grill, Harvey J.

“…Medial nucleus tractus solitarius (mNTS) neurons express leptin receptors (LepRs), and intra-mNTS delivery of leptin reduces food intake and body weight. Here,…”
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Endogenous Leptin Signaling in the Caudal Nucleus Tractus Solitarius and Area Postrema Is Required for Energy Balance Regulation by Hayes, Matthew R., Skibicka, Karolina P., Leichner, Theresa M., Guarnieri, Douglas J., DiLeone, Ralph J., Bence, Kendra K., Grill, Harvey J.

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Intracellular Signals Mediating the Food Intake-Suppressive Effects of Hindbrain Glucagon-like Peptide-1 Receptor Activation by Hayes, Matthew R., Leichner, Theresa M., Zhao, Shiru, Lee, Grace S., Chowansky, Amy, Zimmer, Derek, De Jonghe, Bart C., Kanoski, Scott E., Grill, Harvey J., Bence, Kendra K.

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Both retention and recirculation contribute to long‐lived regulatory T‐cell accumulation in the thymus by Yang, EnJun, Zou, Tao, Leichner, Theresa M., Zhang, Shirley L., Kambayashi, Taku

“…Natural Treg cells acquire their lineage‐determining transcription factor Foxp3 during development in the thymus and are important in maintaining immunologic…”
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NKG2D expression by CD8+ T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT by Karimi, Mobin A., Bryson, Jerrod L., Richman, Lee P., Fesnak, Andrew D., Leichner, Theresa M., Satake, Atsushi, Vonderheide, Robert H., Raulet, David H., Reshef, Ran, Kambayashi, Taku

“…In allogeneic hematopoietic stem cell transplantation (HSCT), controlling graft-versus-host disease (GVHD) while maintaining graft-versus-tumor (GVT) responses…”
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The common hepatic branch of the vagus is not required to mediate the glycemic and food intake suppressive effects of glucagon-like-peptide-1 by Hayes, Matthew R, Kanoski, Scott E, De Jonghe, Bart C, Leichner, Theresa M, Alhadeff, Amber L, Fortin, Samantha M, Arnold, Myrtha, Langhans, Wolfgang, Grill, Harvey J

“…The incretin and food intake suppressive effects of intraperitoneally administered glucagon-like peptide-1 (GLP-1) involve activation of GLP-1 receptors…”
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Skin-derived TSLP systemically expands regulatory T cells by Leichner, Theresa M, Satake, Atsushi, Harrison, Victor Sanoe, Tanaka, Yukinori, Archambault, Angela S, Kim, Brian S, Siracusa, Mark C, Leonard, Warren J, Naji, Ali, Wu, Gregory F, Artis, David, Kambayashi, Taku

“…Abstract Regulatory T cells (Tregs) are a subset of CD4+ T cells with suppressive function and are critical for limiting inappropriate activation of T cells…”
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Diacylglycerol kinase ζ limits the generation of natural regulatory T cells by Schmidt, Amanda M, Zou, Tao, Joshi, Rohan P, Leichner, Theresa M, Pimentel, Matthew A, Sommers, Connie L, Kambayashi, Taku

“…Natural regulatory T (nT(reg)) cells are important for maintaining tolerance to self- and foreign antigens, and they are thought to develop from thymocytes…”
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Differential targeting of IL-2 and T cell receptor signaling pathways selectively expands regulatory T cells while inhibiting conventional T cells by Satake, Atsushi, Schmidt, Amanda M, Archambault, Angela, Leichner, Theresa M, Wu, Gregory F, Kambayashi, Taku

“…Abstract Strategies to expand regulatory T cells hold therapeutic potential for ameliorating T cell-mediated autoimmunity. Recently, we reported that the…”
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TCR signaling by conventional CD4+ T cells is required for optimal maintenance of peripheral regulatory T cell numbers by Leichner, Theresa M., Satake, Atsushi, Kambayashi, Taku

“…To maintain immune tolerance, regulatory T cell (Treg) numbers must be closely indexed to the number of conventional T cells (Tconvs) so that an adequate…”
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Neural Controls of Prostaglandin 2 Pyrogenic, Tachycardic, and Anorexic Actions Are Anatomically Distributed by Skibicka, Karolina P, Alhadeff, Amber L, Leichner, Theresa M, Grill, Harvey J

“…This paper describes a novel perspective on the neural mediation of prostaglandin's effect on fever and anorexia, emphasizing a neuroanatomical distribution of…”
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Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure by De Jonghe, Bart C, Hayes, Matthew R, Banno, Ryoichi, Skibicka, Karolina P, Zimmer, Derek J, Bowen, Kerisha A, Leichner, Theresa M, Alhadeff, Amber L, Kanoski, Scott E, Cyr, Nicole E, Nillni, Eduardo A, Grill, Harvey J, Bence, Kendra K

“…The adipose tissue-derived hormone leptin regulates energy balance through catabolic effects on central circuits, including proopiomelanocortin (POMC) neurons…”
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Transient NKG2D Blockade Attenuates Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia Effects by Karimi, Mobin, Leichner, Theresa M, Satake, Atsushi, Raulet, David, Kambayashi, Taku

“…In allogeneic hematopoietic stem cell transplantation (HSCT), identification of mechanisms to control GVHD yet maintain GVL responses is of critical…”
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Factors influencing regulatory T cell maintenance for the control of autoimmunity by Leichner, Theresa M

“…Regulatory T cells (Tregs) are a subset of CD4+ T cells with suppressive function and are critical in limiting autoimmunity. Increasing Treg numbers can be…”
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