Search Results - "Leibfritz, D"
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Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study
Published in British journal of cancer (24-03-2009)“…The goal of this study was to evaluate the time course of metabolic changes in leukaemia cells treated with the Bcr-Abl tyrosine kinase inhibitor imatinib…”
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Challenges of Using MR Spectroscopy to Detect Neural Progenitor Cells In Vivo
Published in American journal of neuroradiology : AJNR (01-06-2009)“…A recent report of detection of neural progenitor cells (NPCs) in living human brain by using in vivo proton MR spectroscopy ((1)H-MR spectroscopy) has sparked…”
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Metabolic Effects of Dental Resin Components in vitro Detected by NMR Spectroscopy
Published in Journal of dental research (01-03-2001)“…Earlier studies have shown that the comonomer triethyleneglycol-dimethacrylate (TEGDMA) and the photostabilizer 2-hydroxy-4-methoxybenzophenone (HMBP) are…”
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Multinuclear NMR studies on the energy metabolism of glial and neuronal cells
Published in Developmental neuroscience (1993)“…In this multinuclear NMR study myo-inositol is identified as a glia-specific marker for in vivo NMR studies. The unusually high inositol concentration may…”
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Role of Radicals and Singlet Oxygen in Photoactivated DNA Cleavage by the Anticancer Drug Camptothecin: An Electron Paramagnetic Resonance Study
Published in The journal of physical chemistry. B (13-03-2003)“…Camptothecin (CPT) is an anticancer drug that inhibits topoisomerase I (Topo I), an enzyme closely linked to cell division, by forming a ternary DNA−CPT−Topo I…”
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Ammonia toxicity under hyponatremic conditions in astrocytes: De novo synthesis of amino acids for the osmoregulatory response
Published in Neurochemistry international (01-07-2005)“…This study investigates how the metabolic activity and de novo synthesis of amino acids from glucose correlate with changes in intracellular organic osmolytes…”
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Effects of environmental hypercapnia on animal physiology: A 13C NMR study of protein synthesis rates in the marine invertebrate Sipunculus nudus
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-08-2006)“…Global climate change is associated with a progressive rise in ocean CO 2 concentrations (hypercapnia) and, consequently, a drop in seawater pH. However, a…”
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O.003 Negative BOLD-signal in normal pressure hydrocephalus (NPH) patients before and after lumbal puncture
Published in Clinical neurology and neurosurgery (01-01-2008)Get full text
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O.117 Cognitive deficits in idiopathic normal pressure hydrocephalus
Published in Clinical neurology and neurosurgery (01-01-2008)Get full text
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1H-NMR metabolic profiling of human neonatal urine
Published in Magma (New York, N.Y.) (01-12-2006)“…The measurement of different urine components and their changes over time may provide comprehensive and early information about perinatal metabolic processes…”
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Metabolism of acetate in rat brain neurons, astrocytes and cocultures: metabolic interactions between neurons and glia cells, monitored by NMR spectroscopy
Published in Cellular and molecular biology (Noisy-le-Grand, France) (01-07-1997)“…The existence of metabolic compartmentation is generally accepted for the brain because of the specific differences in glial and neuronal metabolism…”
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Fast spectroscopic imaging for non-invasive thermometry using the Pr[MOE-DO3A] complex
Published in Physics in medicine & biology (01-10-1999)“…The praseodymium complex of 10-(2-methoxyethyl)-1,4,7,10-tetraaza-cyclododecane-1,4,7-tr iacetate) was evaluated as a temperature-sensitive contrast agent…”
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Characterization of dimethylguanosine, phenylethylamine, and phenylacetic acid as inhibitors of Ca2+ ATPase in end-stage renal failure
Published in Journal of the American Society of Nephrology (01-07-1998)“…The activity of the plasma membrane Ca2+ ATPase of chronic renal failure patients is decreased by circulating inhibitors yet to be characterized. In this…”
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Inversion recovery snapshot FLASH MR imaging
Published in Journal of computer assisted tomography (01-11-1989)“…Snapshot fast low angle shot (FLASH) magnetic resonance (MR) imaging techniques have been developed to enable real time imaging of MR parameters. The method is…”
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Absolute metabolite quantification by in vivo NMR spectroscopy: I. introduction, objectives and activities of a concerted action in biomedical research
Published in Magnetic resonance imaging (01-11-1998)“…By utilizing achievements and results of two previous concerted research projects on magnetic resonance imaging and spectroscopy (MRS), the EU BIOMED 1…”
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Selective increase of brain lactate synthesis in experimental acute liver failure: Results of a [ 1H- 13C] nuclear magnetic resonance study
Published in Hepatology (Baltimore, Md.) (01-02-2003)“…Acute liver failure (ALF) results in alterations of energy metabolites and of glucose-derived amino acid neurotransmitters in brain. However, the dynamics of…”
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Effect of TEGDMA on the intracellular glutathione concentration of human gingival fibroblasts
Published in Journal of biomedical materials research (2002)“…Previous studies revealed that primarily small and relatively hydrophilic comonomers, such as TEGDMA, leach out of resin‐based restorative materials into…”
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Status of the Neonatal Rat Brain after NMDA-Induced Excitotoxic Injury as Measured by MRI, MRS and Metabolic Imaging
Published in NMR in biomedicine (01-04-1996)“…Intrastriatal injection of the excitotoxin N‐methyl‐dsc‐aspartate (NMDA) in neonatal rat brain resulted in an acute ipsilateral decrease of the apparent…”
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Incidence of apparent restricted diffusion in three different models of cerebral infarction
Published in Magnetic resonance imaging (1994)“…High speed magnetic resonance imaging (MRI) and short diffusion times are used to investigate the appearance of restricted diffusion in three different models…”
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