Search Results - "Lei, Zhenmin"

Confirmation of Luteinizing Hormone (LH) in Living Human Vitreous and the Effect of LH Receptor Reduction on Murine Electroretinogram by Movsas, Tammy Z., Wong, Kwoon Y., Ober, Michael D., Sigler, Robert, Lei, Zhenmin M., Muthusamy, Arivalagan

“…•Luteinizing hormone (LH) is reliably present in all living, adult human eyes.•Proliferative diabetic retinopathy (PDR) is associated with increased vitreous…”
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Lhb -/- Lhr -/- Double Mutant Mice Phenocopy Lhb -/- or Lhr -/- Single Mutants and Display Defects in Leydig Cells and Steroidogenesis by Liu, Zhenghui, Larsen, Mark, Lei, Zhenmin, Rao, C V, Kumar, T Rajendra

“…In the mouse, two distinct populations of Leydig cells arise during testis development. Fetal Leydig cells arise from a stem cell population and produce T…”
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Dysregulation of Notch-FGF signaling axis in germ cells results in cystic dilation of the rete testis in mice by Cao, Yin, Liu, Lingyun, Lin, Jing, Sun, Penghao, Guo, Kaimin, Li, Shengqiang, Li, Xian, Lan, Zi-jian, Wang, Hongliang, Lei, Zhenmin

“…Numb (Nb) and Numb-like (Nbl) are functionally redundant adaptor proteins that critically regulate cell fate and morphogenesis in a variety of organs. We…”
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The Vaginal and Urinary Microbiomes in Premenopausal Women With Interstitial Cystitis/Bladder Pain Syndrome as Compared to Unaffected Controls: A Pilot Cross-Sectional Study by Meriwether, Kate V, Lei, Zhenmin, Singh, Rajbir, Gaskins, Jeremy, Hobson, Deslyn T G, Jala, Venkatakrishna

“…Interstitial cystitis/bladder pain syndrome (ICBPS) may be related to an altered genitourinary microbiome. Our aim was to compare the vaginal and urinary…”
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The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells by Tanaka, Takashi, Kanatsu-Shinohara, Mito, Lei, Zhenmin, Rao, C.V., Shinohara, Takashi

“…Spermatogenesis originates from self-renewal of spermatogonial stem cells (SSCs). Previous studies have reported conflicting roles of gonadotropic pituitary…”
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Aberrant activation of KRAS in mouse theca-interstitial cells results in female infertility by Sun, Penghao, Wang, Hongliang, Liu, Lingyun, Guo, Kaimin, Li, Xian, Cao, Yin, Ko, Chemyong, Lan, Zi-Jian, Lei, Zhenmin

“…KRAS plays critical roles in regulating a range of normal cellular events as well as pathological processes in many tissues mediated through a variety of…”
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Non-peptidyl small molecule, adenosine, 5′-Se-methyl-5′-seleno-, 2′,3′-diacetate, activates insulin receptor and attenuates hyperglycemia in type 2 diabetic Leprdb/db mice by Lan, Zi-Jian, Lei, Zhenmin, Yiannikouris, Alexandros, Yerramreddy, Thirupathi Reddy, Li, Xian, Kincaid, Hayley, Eastridge, Katie, Gadberry, Hannah, Power, Chloe, Xiao, Rijin, Lei, Lei, Seale, Olivia, Dawson, Karl, Power, Ronan

“…The pathophysiology of type 2 diabetes mellitus (T2D) is characterized by reduced or absent insulin receptor (INSR) responsiveness to its ligand, elevated…”
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Epidermal growth factor receptor and AKT1 gene copy numbers by multi‐gene fluorescence in situ hybridization impact on prognosis in breast cancer by Li, Jiao, Su, Wei, Zhang, Sheng, Hu, Yunhui, Liu, Jingjing, Zhang, Xiaobei, Bai, Jingchao, Yuan, Weiping, Hu, Linping, Cheng, Tao, Zetterberg, Anders, Lei, Zhenmin, Zhang, Jin

“…The epidermal growth factor receptor (EGFR)/PI3K/AKT signaling pathway aberrations play significant roles in breast cancer occurrence and development. However,…”
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Memantine reduces mania-like symptoms in animal models by Gao, Yonglin, Payne, Ralphiel S, Schurr, Avital, Hougland, Tyler, Lord, Joshua, Herman, Laura, Lei, Zhenmin, Banerjee, Pradeep, El-Mallakh, Rif S

“…Abstract Memantine, a selective antagonist of the N -methyl-D-aspartate receptor, is approved for the treatment of moderate to severe Alzheimer's disease. Ion…”
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Genetic Ablation of Luteinizing Hormone Receptor Improves the Amyloid Pathology in a Mouse Model of Alzheimer Disease by Lin, Jing, Li, Xian, Yuan, Fangping, Lin, Ling, Cook, Christine L, Rao, Ch V, Lei, Zhenmin

“…Amyloid-β peptide (Aβ) plays an essential pathophysiologic role in Alzheimer disease, and elevation of luteinizing hormone (LH) levels during aging has been…”
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Olfactory Neuroepithelial Neural Progenitor Cells from Subjects with Bipolar I Disorder by Gao, Yonglin, Winstead, Welby, Lei, Zhenmin, Lu, Chengliang, Roisen, Fred J., El-Mallakh, Rif S.

“…Background: Research into the pathophysiology of bipolar disorder (BD) is limited by the inability to examine brain cellular processes in subjects with the…”
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De Novo Testosterone Production in Luteinizing Hormone Receptor Knockout Mice after Transplantation of Leydig Stem Cells by Lo, Kirk C, Lei, Zhenmin, Rao, Ch. Venkateswara, Beck, Josie, Lamb, Dolores J

“…Mesenchymal stem cells or Leydig cell progenitors are rare and difficult to isolate from adult testes. The property of differential efflux of Hoechst 33342 dye…”
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Effect of ouabain on sodium pump alpha-isoform expression in an animal model of mania by Hamid, Humera, Gao, YongLin, Lei, Zhenmin, Hougland, M. Tyler, El-Mallakh, Rif S.

“…While the pathophysiologic mechanisms of bipolar illness are unknown, a dysregulation of electrolytes, particularly intracellular sodium (Na) and calcium (Ca),…”
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Expression of zinc finger protein 105 in the testis and its role in male fertility by Zhou, Huaxin, Liu, Lan-Hsin, Zhang, Heng, Lei, Zhenmin, Lan, Zi-Jian

“…Using an in silico approach, we identified a putative zinc finger domain‐containing transcription factor (zinc finger protein 105, ZFP105) enriched in the…”
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Follicle-Stimulating Hormone Receptor (FSHR), Müllerian-Inhibiting Substance (MIS), and MIS-II Receptor Expression in Human Ovarian Preantral Follicle Stages by McCoy, Travis W, Li, Xian, Nakajima, Steven T, Fallat, Mary E, Lei, Zhenmin M, Siow, Yong

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Effects of brain-derived neurotrophic factor on sodium-induced apoptosis in human olfactory neuroepithelial progenitor cells by Willett, Lindsey, Gao, Yonglin, Lei, Zhenmin, Lu, Chengling, Roisen, Fred J, Winstead, Welby I, El-Mallakh, Rif S

“…Abstract Low levels of brain-derived neurotrophic factor (BDNF) peptide are linked to the pathophysiology of mood disorders. Several single-nucleotide…”
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Virilization in Bilateral Macronodular Adrenal Hyperplasia Controlled by Luteinizing Hormone by Goodarzi, Mark O., Dawson, David W., Li, Xian, Lei, Zhenmin, Shintaku, Peter, Rao, Chalama V., Van Herle, Andre J.

“…We report a case of a virilized 59-yr-old woman with elevated serum testosterone levels and bilateral macronodular adrenal hyperplasia. The patient underwent…”
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Positron emission tomography with fluorodeoxyglucose-F18 in an animal model of mania by Hougland, Matthew Tyler, Gao, Yonglin, Herman, Laura, Ng, Chin K, Lei, Zhenmin, El-Mallakh, Rif S

“…Abstract Intracerebroventricular (ICV) administration of ouabain to young adult rats has been suggested to model human bipolar mania. In the human condition,…”
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Chromatin Immunoprecipitation with Estrogen Receptor 1 and the Promoter of Greb1 in TM4 Sertoli Cells by Lin, Jing, Lei, Zhenmin

“…Chromatin immunoprecipitation (ChIP) is a technique to investigate the interaction between proteins and DNA within the natural chromatin context of the cell…”
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GGNBP2 to suppress tumor growth and cancer stem cell load of triple negative breast cancer by controlling STAT3 pathway by Zhang, Jin, Hu, Yunhui, Lei, Zhenmin

“…Abstract only e23003 Background: Gametogenetin binding protein 2 (GGNBP2) is encoded in human chromosome 17q12-q23, a region known as a breast and ovarian…”
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