Search Results - "Lei, Winnie"

SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers by Jones, Greg G., del Río, Isabel Boned, Sari, Sibel, Sekerim, Aysen, Young, Lucy C., Hartig, Nicole, Areso Zubiaur, Itziar, El-Bahrawy, Mona A., Hynds, Rob E., Lei, Winnie, Molina-Arcas, Miriam, Downward, Julian, Rodriguez-Viciana, Pablo

“…Targeted inhibition of the ERK-MAPK pathway, upregulated in a majority of human cancers, has been hindered in the clinic by drug resistance and toxicity. The…”
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SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics by del Río, Isabel Boned, Young, Lucy C., Sari, Sibel, Jones, Greg G., Ringham-Terry, Benjamin, Hartig, Nicole, Rejnowicz, Ewa, Lei, Winnie, Bhamra, Amandeep, Surinova, Silvia, Rodriguez-Viciana, Pablo

“…Despite the crucial role of RAF kinases in cell signaling and disease, we still lack a complete understanding of their regulation. Heterodimerization of RAF…”
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House of Cards—An analysis of Macao’s resident support for tourism and casino development by McCartney, Glenn, In, Winnie Lei Weng

“…Tourism contribution to Macao’s gross domestic product in 2013 was 86% positioning it as a global leader in terms of reliance on tourism revenues, to which…”
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Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies by Han, Namshik, Hwang, Woochang, Tzelepis, Konstantinos, Schmerer, Patrick, Yankova, Eliza, MacMahon, Méabh, Lei, Winnie, M Katritsis, Nicholas, Liu, Anika, Felgenhauer, Ulrike, Schuldt, Alison, Harris, Rebecca, Chapman, Kathryn, McCaughan, Frank, Weber, Friedemann, Kouzarides, Tony

“…The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates the rapid development of new therapies against coronavirus…”
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Management of Acute Appendicitis During the COVID-19 Pandemic: A Single-Centre Retrospective Cohort Study by Afzal, Zeeshan, Bukhari, Ishtiyaq, Kumar, Sumit, Deeknah, Abdulqudus, Lei, Winnie, Mitrasinovic, Stefan, Chan, Onton, Francis, Francesca E, Satheesan, Kanagasingham S

“…During the coronavirus disease 2019 (COVID-19) pandemic, the management of acute appendicitis shifted towards non-operative management in the United Kingdom…”
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Current and prospective computational approaches and challenges for developing COVID-19 vaccines by Hwang, Woochang, Lei, Winnie, Katritsis, Nicholas M, MacMahon, Méabh, Chapman, Kathryn, Han, Namshik

“…[Display omitted] SARS-CoV-2, which causes COVID-19, was first identified in humans in late 2019 and is a coronavirus which is zoonotic in origin. As it spread…”
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CAN GOLDMANN TONOMETER TIPS BE EFFECTIVELY DISINFECTED WITH 70% ALCOHOL PADS SEVERAL HOURS AFTER USE?: Poster #98 by LaMotte, James, Chiao, Elaina, Lei, Winnie

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