Search Results - "Lei, Tim"
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1
Light scattering properties vary across different regions of the adult mouse brain
Published in PloS one (09-07-2013)“…Recently developed optogenetic tools provide powerful approaches to optically excite or inhibit neural activity. In a typical in-vivo experiment, light is…”
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2
A fully automatic multichannel neural spike sorting algorithm with spike reduction and positional feature
Published in Journal of neural engineering (01-08-2024)“…: The sorting of neural spike data recorded by multichannel and high channel neural probes such as Neuropixels, especially in real-time, remains a significant…”
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3
Low-latency single channel real-time neural spike sorting system based on template matching
Published in PloS one (22-11-2019)“…Recent technical advancements in neural engineering allow for precise recording and control of neural circuits simultaneously, opening up new opportunities for…”
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4
A method for non-destructive microwave focusing for deep brain and tissue stimulation
Published in PloS one (09-02-2023)“…Non-invasive stimulation of biological tissue is highly desirable for several biomedical applications. Of specific interest are methods for tumor treatment,…”
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5
Automatic detection and quantification of hand movements toward development of an objective assessment of tremor and bradykinesia in Parkinson's disease
Published in Journal of neuroscience methods (01-03-2020)“…•Recognize and detect hand movements during standardized clinical assessment.•Analyze joint displacement for bradykinesia during clinical examination.•Analyze…”
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6
Robotic stereotaxic system based on 3D skull reconstruction to improve surgical accuracy and speed
Published in Journal of neuroscience methods (01-01-2021)“…[Display omitted] •A fully automated stereotaxic system for small rodents using 3D computer vision and full 6 degree-of-freedom (DOFs) robotic platform.•3D…”
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7
Oxytocin modulates neural processing of mitral/tufted cells in the olfactory bulb
Published in Acta Physiologica (01-04-2021)“…Aim Oxytocin plays an important role in social recognition in rodents, which is mediated predominantly by the olfactory system. Although oxytocin modulates…”
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8
Hearing ability of prairie voles (Microtus ochrogaster)
Published in The Journal of the Acoustical Society of America (01-01-2024)“…The hearing abilities of mammals are impacted by factors such as social cues, habitat, and physical characteristics. Despite being used commonly to study…”
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9
An Integrated Circuit for Simultaneous Extracellular Electrophysiology Recording and Optogenetic Neural Manipulation
Published in IEEE transactions on biomedical engineering (01-03-2017)“…Objective: The ability to record and to control action potential firing in neuronal circuits is critical to understand how the brain functions. The objective…”
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10
Predicting the Influence of Axon Myelination on Sound Localization Precision Using a Spiking Neural Network Model of Auditory Brainstem
Published in Frontiers in neuroscience (14-03-2022)“…Spatial hearing allows animals to rapidly detect and localize auditory events in the surrounding environment. The auditory brainstem plays a central role in…”
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11
Photodynamic therapy via navigational bronchoscopy for peripheral lung cancer in dogs
Published in Lasers in surgery and medicine (01-07-2018)“…Objective In the setting of lung cancer, photodynamic therapy (PDT) is typically used to treat centrally located endobronchial tumors. The development of…”
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Evaluation of lensed fibers used in photodynamic therapy (PDT)
Published in Photodiagnosis and photodynamic therapy (01-09-2020)“…Lensed optical fibers are very useful for the frontal irradiation of superficial lesions in PDT applications. This study demonstrated that using microlens…”
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13
Double-Sided Sapphire Optrodes with Conductive Shielding Layers to Reduce Optogenetic Stimulation Artifacts
Published in Micromachines (Basel) (27-10-2022)“…Optrodes, which are single shaft neural probes integrated with microelectrodes and optical light sources, offer a remarkable opportunity to simultaneously…”
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14
Coherent anti-stokes Raman scattering (CARS) microscopy: a novel technique for imaging the retina
Published in Investigative ophthalmology & visual science (01-05-2013)“…To image the cellular and noncellular structures of the retina in an intact mouse eye without the application of exogenous fluorescent labels using…”
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15
A recording chamber for small volume slice electrophysiology
Published in Journal of neurophysiology (01-09-2015)“…Electrophysiological recordings from brain slices are typically performed in small recording chambers that allow for the superfusion of the tissue with…”
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16
Role of PDZK1 Protein in Apical Membrane Expression of Renal Sodium-coupled Phosphate Transporters
Published in The Journal of biological chemistry (29-04-2011)“…The sodium-dependent phosphate (Na/Pi) transporters NaPi-2a and NaPi-2c play a major role in the renal reabsorption of Pi. The functional need for several…”
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17
Imaging the intact mouse cornea using coherent anti-stokes Raman scattering (CARS)
Published in Investigative ophthalmology & visual science (05-08-2013)“…The aim of this study was to image the cellular and noncellular structures of the cornea and limbus in an intact mouse eye using the vibrational oscillation of…”
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18
Quantitative assessment of skin swelling using optical coherence tomography
Published in Photodiagnosis and photodynamic therapy (01-06-2019)“…Mouse ear model was used to evaluate OCT imaging of cutaneous swelling induced by histamine. 3D scan was obtained by a frequency domain OCT to visualize…”
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Three-Dimensional Segmentation and Quantitative Measurement of the Aqueous Outflow System of Intact Mouse Eyes Based on Spectral Two-Photon Microscopy Techniques
Published in Investigative ophthalmology & visual science (01-06-2016)“…To visualize and quantify the three-dimensional (3D) spatial relationships of the structures of the aqueous outflow system (AOS) within intact enucleated mouse…”
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20
Direct trabecular meshwork imaging in porcine eyes through multiphoton gonioscopy
Published in Journal of biomedical optics (01-03-2013)“…The development of technologies to characterize the ocular aqueous outflow system (AOS) is important for the understanding of the pathophysiology of glaucoma…”
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