Search Results - "Lei, Guanghua"

Targeted apoptosis of macrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis by Deng, Caifeng, Zhang, Quan, He, Penghui, Zhou, Bin, He, Ke, Sun, Xun, Lei, Guanghua, Gong, Tao, Zhang, Zhirong

“…Insufficient apoptosis of inflammatory macrophages and osteoclasts (OCs) in rheumatoid arthritis (RA) joints contributes toward the persistent progression of…”
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Length of stay and inpatient charges of total knee arthroplasty in China: analysis of a national database by Long, Huizhong, Zeng, Chao, Shi, Ying, Wang, Haibo, Xie, Dongxing, Lei, Guanghua

“…There are limited data on the resource utilization of total knee arthroplasty (TKA) in China. This study aimed to examine the length of stay (LOS) and…”
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Gut dysbiosis in rheumatic diseases: A systematic review and meta-analysis of 92 observational studies by Wang, Yilun, Wei, Jie, Zhang, Weiya, Doherty, Michael, Zhang, Yuqing, Xie, Haibin, Li, Wei, Wang, Ning, Lei, Guanghua, Zeng, Chao

“…Emerging evidence suggests that dysbiosis in gut microbiota may contribute to the occurrence or development of several rheumatic diseases. Since gut microbiota…”
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Physical Distancing Measures and Walking Activity in Middle-aged and Older Residents in Changsha, China, During the COVID-19 Epidemic Period: Longitudinal Observational Study by Wang, Yilun, Zhang, Yuqing, Bennell, Kim, White, Daniel Kenta, Wei, Jie, Wu, Ziying, He, Hongyi, Liu, Shaohui, Luo, Xianghang, Hu, Shuo, Zeng, Chao, Lei, Guanghua

“…Physical distancing measures taken to contain COVID-19 transmission may substantially reduce physical activity levels and cause individuals to adopt a more…”
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Exploration of metformin as novel therapy for osteoarthritis: preventing cartilage degeneration and reducing pain behavior by Li, Hui, Ding, Xiang, Terkeltaub, Robert, Lin, Hang, Zhang, Yuqing, Zhou, Bin, He, Ke, Li, Kun, Liu, Zhichen, Wei, Jie, Yang, Yuanheng, Xie, Hui, Zeng, Chao, Lei, Guanghua

“…Metformin could activate adenosine monophosphate-activated protein kinase (AMPK) which was postulated as a potential therapeutic target for osteoarthritis…”
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Genetically Predicted Levels of Serum Metabolites and Risk of Sarcopenia: A Mendelian Randomization Study by Sha, Tingting, Wang, Ning, Wei, Jie, He, Hongyi, Wang, Yilun, Zeng, Chao, Lei, Guanghua

“…Metabolites’ connection to sarcopenia through inflammation and mitochondrial dysfunction is presumed, but their impact remains unclear due to limitations in…”
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Diagnostic accuracy of ultrasound for the assessment of Baker's cysts: a meta-analysis by Liu, Ke, Li, Xiaoxiao, Weng, Qianlin, Lei, Guanghua, Jiang, Ting

“…Baker's cyst is the most common cystic disease of the knee, and a fast and accurate diagnosis of Baker's cyst is essential for a better management. Ultrasound…”
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Increased Wnt/β-catenin signaling contributes to autophagy inhibition resulting from a dietary magnesium deficiency in injury-induced osteoarthritis by Bai, Ruijun, Miao, Michael Z., Li, Hui, Wang, Yiqing, Hou, Ruixue, He, Ke, Wu, Xuan, Jin, Hongyu, Zeng, Chao, Cui, Yang, Lei, Guanghua

“…Abstract Background Dietary magnesium deficiency, which is common in modern diet, has been associated with osteoarthritis (OA) susceptibility. Despite this…”
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Population‐based metagenomics analysis reveals altered gut microbiome in sarcopenia: data from the Xiangya Sarcopenia Study by Wang, Yilun, Zhang, Yuqing, Lane, Nancy E., Wu, Jing, Yang, Tuo, Li, Jiatian, He, Hongyi, Wei, Jie, Zeng, Chao, Lei, Guanghua

“…Background Several studies have examined gut microbiota and sarcopenia using 16S ribosomal RNA amplicon sequencing; however, this technique may not be able to…”
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Inflammatory potential of diet and risk of incident knee osteoarthritis: a prospective cohort study by Liu, Qiang, Hebert, James R., Shivappa, Nitin, Guo, Jianjun, Tao, Ke, Zeng, Chao, Lei, Guanghua, Lin, Jianhao, Zhang, Yuqing

“…Abstract Background To examine the relation between inflammatory potential of diet and incident knee osteoarthritis (OA) and the role of BMI in the association…”
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The efficiency and safety of steroid addition to multimodal cocktail periarticular injection in knee joint arthroplasty: a meta-analysis of randomized controlled trials by Deng, Zhenhan, Li, Yusheng, Storm, Garrett R., Kotian, Ronak Naveenchandra, Sun, Xuying, Lei, Guanghua, Gao, Shanshan, Lu, Wei

“…Steroids are frequently used for postoperative pain relief without definite evidence. This study was conducted to assess the pain management effect of the…”
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Outcomes of Anterior Cruciate Ligament Reconstruction Using Single-Bundle Versus Double-Bundle Technique: Meta-analysis of 19 Randomized Controlled Trials by Xu, Mai, M.D., Ph.D, Gao, Shuguang, M.D., Ph.D, Zeng, Chao, M.D, Han, Rui, B.N, Sun, Jinpeng, M.D, Li, Hui, M.D, Xiong, Yilin, M.D, Lei, Guanghua, M.D., Ph.D

“…Purpose The purpose of this study was to test the hypothesis that double-bundle anterior cruciate ligament reconstruction yields better improvement in…”
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Macrophage migration inhibitory factor may play a protective role in osteoarthritis by Liu, Ming, Xie, Zikun, Sun, Guang, Chen, Liujun, Qi, Dake, Zhang, Hongwei, Xiong, Jieying, Furey, Andrew, Rahman, Proton, Lei, Guanghua, Zhai, Guangju

“…Osteoarthritis (OA) is the most prevalent form of arthritis and the major cause of disability and overall diminution of quality of life in the elderly…”
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miR-188-3p targets skeletal endothelium coupling of angiogenesis and osteogenesis during ageing by He, Wen-Zhen, Yang, Mi, Jiang, Yangzi, He, Chen, Sun, Yu-Chen, Liu, Ling, Huang, Mei, Jiao, Yu-Rui, Chen, Kai-Xuan, Hou, Jing, Huang, Min, Xu, Yi-Li, Feng, Xu, Liu, Ya, Guo, Qi, Peng, Hui, Huang, Yan, Su, Tian, Xiao, Ye, Li, Yusheng, Zeng, Chao, Lei, Guanghua, Luo, Xiang-Hang, Li, Chang-Jun

“…A specific bone capillary subtype, namely type H vessels, with high expression of CD31 and endomucin, was shown to couple angiogenesis and osteogenesis…”
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Phenotypes of osteoarthritis-related knee pain and their transition over time: data from the osteoarthritis initiative by Ye, Jing, Xie, Dongxing, Li, Xiaoxiao, Lu, Na, Zeng, Chao, Lei, Guanghua, Wei, Jie, Li, Jiatian

“…Identification of knee osteoarthritis (OA) pain phenotypes, their transition patterns, and risk factors for worse phenotypes, may guide prognosis and targeted…”
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Diet-Intestinal Microbiota Axis in Osteoarthritis: A Possible Role by Lei, Guanghua, Deng, Zhenhan, Luo, Wei, Li, Yusheng

“…Intestinal microbiota is highly involved in host physiology and pathology through activity of the microbiome and its metabolic products. Osteoarthritis (OA) is…”
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MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes by Tu, Min, Li, Yusheng, Zeng, Chao, Deng, Zhenhan, Gao, Shuguang, Xiao, Wenfeng, Luo, Wei, Jiang, Wei, Li, Liangjun, Lei, Guanghua

“…The aim of this study was to determine the specific microRNA (miRNA) that regulates expression of osteopontin (OPN) in osteoarthritis (OA). The potential…”
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Secular trend of gout incidence in the UK: an age-period-cohort analysis by Ye, Jing, Zhang, Yuqing, Zhang, Weiya, Doherty, Michael, Lu, Na, Zeng, Chao, Lei, Guanghua, Wei, Jie, Ding, Xiang

“…ObjectivesThe incidence of gout in the UK appears to have declined since 2013; however, whether such a trend occurred across participants born in different…”
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Comparative effectiveness of BNT162b2 and ChAdOx1 nCoV-19 vaccines against COVID-19 by Wei, Jie, Zhang, Weiya, Doherty, Michael, Wallace, Zachary S, Sparks, Jeffrey A, Lu, Na, Li, Xiaoxiao, Zeng, Chao, Lei, Guanghua, Zhang, Yuqing

“…Both BNT162b2 (Pfizer-BioNTech) and ChAdOx1 nCoV-19 (Oxford-AstraZeneca) vaccines have shown high efficacy against COVID-19 in randomized controlled trials…”
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Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population—the Xiangya Osteoarthritis Study by Jiang, Ting, Yang, Tuo, Zhang, Weiya, Doherty, Michael, Zhang, Yuqing, Wei, Jie, Sarmanova, Aliya, Hall, Michelle, Yang, Zidan, Li, Jiatian, Fernandes, Gwen S, Obotiba, Abasiama D, Gohir, Sameer A, Courtney, Philip, Zeng, Chao, Lei, Guanghua

“…Abstract Background There is paucity of data on the prevalence of ultrasound-detected synovial abnormalities in the general population, and the relationship…”
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