Search Results - "Lehtovirta, Maarit"

Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers by Iqbal, Khalid, Flory, Michael, Khatoon, Sabiha, Soininen, Hilkka, Pirttila, Tuula, Lehtovirta, Maarit, Alafuzoff, Irina, Blennow, Kaj, Andreasen, Niels, Vanmechelen, Eugeen, Grundke-Iqbal, Inge

“…Alzheimer's disease, the most common cause of dementia, is multifactorial and heterogeneous; its diagnosis remains probable. We postulated that more than one…”
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Hippocampus in Alzheimer’s disease: a 3-year follow-up MRI study by Laakso, Mikko P, Lehtovirta, Maarit, Partanen, Kaarina, Riekkinen, Paavo J, Soininen, Hilkka

“…Background: Due to the progressive nature of Alzheimer’s disease (AD), it has been proposed that serial imaging studies tracking the course of progression…”
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TU-190. Principal component analysis of auditory ERPs discriminates mild cognitive impairment and Alzheimer’s disease from normal aging by Liljander, Sara K., Nieminen, Jaakko O., Keski-Säntti, Petra, Mutanen, Tuomas P., Lehtovirta, Maarit, Ilmoniemi, Risto J., Partanen, Juhani V.

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Principal component analysis of auditory ERPs discriminates mild cognitive impairment and Alzheimer’s disease from normal aging by Liljander, Sara K., Nieminen, Jaakko O., Keski‐Säntti, Petra, Mutanen, Tuomas P., Lehtovirta, Maarit, Ilmoniemi, Risto J., Partanen, Juhani V.

“…Background Sensory gating refers to an inhibitory mechanism of the brain that protects higher cortical centers from being flooded with repetitive, redundant…”
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CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles : new clues to Batten disease by LUIRO, Kaisu, KOPRA, Outi, LEHTOVIRTA, Maarit, JALANKO, Anu

“…Batten disease (juvenile neuronal ceroid lipofuscinosis, JNCL), the most common neurodegenerative disease of childhood, is caused by mutations in the CLN3 gene…”
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Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women by PIRSKANEN, Mia, HILTUNEN, Mikko, MANNERMAA, Arto, HELISALMI, Seppo, LEHTOVIRTA, Maarit, HÄNNINEN, Tuomo, SOININEN, Hilkka

“…We investigated the association of five intronic single-nucleotide polymorphism (SNP) at the estrogen receptor beta (ESR2) gene locus and the susceptibility of…”
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Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons : implications for infantile neuronal ceroid lipofuscinosis (INCL) by LEHTOVIRTA, Maarit, KYTTÄLÄ, Aija, ESKELINEN, Eeva-Liisa, HESS, Michael, HEINONEN, Outi, JALANKO, Anu

“…A deficiency of palmitoyl protein thioesterase (PPT) leads to the neurodegenerative disease infantile neuronal ceroid lipofuscinosis (INCL), which is…”
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Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease by VEPSÄLÄINEN, Saila, CASTREN, Eero, HELISALMI, Seppo, IIVONEN, Susan, MANNERMAA, Arto, LEHTOVIRTA, Maarit, HÄNNINEN, Tuomo, SOININEN, Hilkka, HILTUNEN, Mikko

“…According to previous biochemical and genetic findings, brain-derived neurotrophic factor (BDNF), via activation of its tyrosine kinase receptor B (TrkB), is…”
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Defective Intracellular Transport of CLN3 is the Molecular Basis of Batten Disease (JNCL) by Järvelä, Irma, Lehtovirta, Maarit, Tikkanen, Ritva, Kyttälä, Aija, Jalanko, Anu

“…Batten disease [juvenile-onset neuronal ceroid lipofuscinosis (JNCL)], the most common progressive encephalopathy of childhood, is caused by mutations in a…”
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Relationship between apoE genotype and CSF β-amyloid (1–42) and tau in patients with probable and definite Alzheimer’s disease by Tapiola, Tero, Pirttilä, Tuula, Mehta, Pankaj D., Alafuzoff, Irina, Lehtovirta, Maarit, Soininen, Hilkka

“…We investigated the usefulness of cerebrospinal fluid (CSF) β-amyloid42 (Aβ42), β-amyloid40 (Aβ40) and tau analyses in the diagnosis of Alzheimer’s disease…”
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The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimerʼs disease by Tapiola, Tero, Overmyer, Margit, Lehtovirta, Maarit, Helisalmi, Seppo, Ramberg, Jarmo, Alafuzoff, Irina, Riekkinen, Paavo, Soininen, Hilkka

“…WE measured tau concentrations in cerebrospinal fluid (CSF) samples taken during the lifetime of 43 patients with Alzheimerʼs disease (AD) and correlated these…”
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Genetic variation in apolipoprotein D and Alzheimer's disease by HELISALMI, Seppo, HILTUNEN, Mikko, VEPSÄLÄINEN, Saila, IIVONEN, Susan, CORDER, Elizabeth H, LEHTOVIRTA, Maarit, MANNERMAA, Arto, KOIVISTO, Anne Maria, SOININEN, Hilkka

“…Apolipoprotein D (apoD) is a lipoprotein-associated glycoprotein, structurally unrelated to apoE, that transports small hydrophobic ligands including…”
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How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer’s disease? A review of neuroimaging studies by Lehtovirta, Maarit, Laakso, Mikko P, Frisoni, Giovanni B, Soininen, Hilkka

“…The ϵ4 allele of apolipoprotein E is a risk factor for Alzheimer’s disease, but also a modulator of its clinical picture. In this paper, recent research in…”
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P4-082 Polymorphisms in the CYP19 gene confer increased risk for Alzheimer's disease by Iivonen, Susan, Corder, Elizabeth H., Lehtovirta, Maarit, Helisalmi, Seppo, Mannermaa, Arto, Vepsäläinen, Saila, Hänninen, Tuomo, Soininen, Hilkka, Hiltunen, Mikko

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P4-123 Genetic analysis of BDNF and TRKB gene polymorphisms in Alzheimer's disease by Vepsäläinen, Saila H., Castren, Eero, Lehtovirta, Maarit, Iivonen, Susan, Helisalmi, Seppo, Mannermaa, Arto, Hänninen, Tuomo, Soininen, Hilkka, Hiltunen, Mikko

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Heparan sulfate proteoglycan 2 polymorphism in Alzheimer's disease and correlation with neuropathology by Iivonen, Susan, Helisalmi, Seppo, Mannermaa, Arto, Alafuzoff, Irina, Lehtovirta, Maarit, Soininen, Hilkka, Hiltunen, Mikko

“…A genetic association of an intronic single nucleotide polymorphism site of heparan sulfate proteoglycan 2 (HSPG2) with Alzheimer's disease (AD) was…”
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Identification of a novel 4.6-kb genomic deletion in presenilin-1 gene which results in exclusion of exon 9 in a Finnish early onset Alzheimer's disease family: an Alu core sequence-stimulated recombination? by Hiltunen, M, Helisalmi, S, Mannermaa, A, Alafuzoff, I, Koivisto, A M, Lehtovirta, M, Pirskanen, M, Sulkava, R, Verkkoniemi, A, Soininen, H

“…Mutations in the presenilin-1 (PS-1) gene have been shown to cause early onset Alzheimer's disease (EOAD) in an autosomal dominant manner. We have identified a…”
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Subgroups of Alzheimer disease based on cerebrospinal fluid levels of molecular markers by Iqbal, Khalid, Flory, Michael, Khatoon, Sabiha, Soininen, Hilkka, Pirttila, Tuula, Lehtovirta, Maarit, Blennow, Kaj, Andreasen, Niels, Vanmechelen, Eugeen, Grundke-Iqbal, Inge

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A longitudinal quantitative EEG study of Alzheimer's disease: relation to apolipoprotein E polymorphism by Lehtovirta, M, Partanen, J, Könönen, M, Hiltunen, J, Helisalmi, S, Hartikainen, P, Riekkinen, Sr, P, Soininen, H

“…Apolipoprotein E (apoE) sigma4 allele is a risk factor for late-onset Alzheimer's disease (AD) and is proposed to have an impact on cholinergic function in AD…”
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Increased risk of sensorineural hearing loss and migraine in patients with a rare mitochondrial DNA variant 4336AG in tRNA [Gln] by Finnila, Saara, Autere, Jaana, Lehtovirta, Maarit, Ha, Mannermaa, Arto, Soininen, Hilkka, Majamaa, Kari

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