Search Results - "Lehtonen, Š."

Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner by Räsänen, Noora, Tiihonen, Jari, Koskuvi, Marja, Lehtonen, Šárka, Jalkanen, Nelli, Karmila, Nelli, Weert, Isabelle, Vaurio, Olli, Ojansuu, Ilkka, Lähteenvuo, Markku, Pietiläinen, Olli, Koistinaho, Jari

“…Development of synaptic activity is a key neuronal characteristic that relies largely on interactions between neurons and astrocytes. Although astrocytes have…”
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Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex by Lehtonen, S.

“…Uchida et al. show in this issue that in rat and human nephrosis, tyrosine phosphorylation of nephrin is reduced, and this is accompanied by a decrease in…”
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Phylogenetic Network for European mtDNA by Finnilä, Saara, Lehtonen, Mervi S., Majamaa, Kari

“…The sequence in the first hypervariable segment (HVS-I) of the control region has been used as a source of evolutionary information in most phylogenetic…”
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Gut changes as potential trigger for Parkinson's disease by Syvänen, V., Lehtonen, Š., Räty, K., Jalkanen, A.

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Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway by Saurus, P, Kuusela, S, Lehtonen, E, Hyvönen, M E, Ristola, M, Fogarty, C L, Tienari, J, Lassenius, M I, Forsblom, C, Lehto, M, Saleem, M A, Groop, P-H, Holthöfer, H, Lehtonen, S

“…High serum lipopolysaccharide (LPS) activity in normoalbuminuric patients with type 1 diabetes (T1D) predicts the progression of diabetic nephropathy (DN), but…”
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Tankyrase inhibition aggravates kidney injury in the absence of CD2AP by Kuusela, S, Wang, H, Wasik, A A, Suleiman, H, Lehtonen, S

“…Inappropriate activation of the Wnt/ β -catenin pathway has been indicated in podocyte dysfunction and injury, and shown to contribute to the development and…”
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Breast cancer carcinoma-associated fibroblasts differ from breast fibroblasts in immunological and extracellular matrix regulating pathways by Pasanen, I., Lehtonen, S., Sormunen, R., Skarp, S., Lehtilahti, E., Pietilä, M., Sequeiros, R. Blanco, Lehenkari, P., Kuvaja, P.

“…Tumor stroma has been recently shown to play a crucial role in the development of breast cancer. Since the origin of the stromal cells in the tumor is unknown,…”
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Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma by Kinnula, V. L., Lehtonen, S., Sormunen, R., Kaarteenaho-Wiik, R., Kang, S. W., Rhee, S. G., Soini, Y.

“…Peroxiredoxins (Prxs) are a recently characterized group of thiol‐containing proteins with efficient antioxidant capacity, capable of consuming hydrogen…”
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Miniature atomic scalar magnetometer for space based on the rubidium isotope 87 Rb by Korth, Haje, Strohbehn, Kim, Tejada, Francisco, Andreou, Andreas G, Kitching, John, Knappe, Svenja, Lehtonen, S John, London, Shaughn M, Kafel, Matiwos

“…A miniature atomic scalar magnetometer based on the rubidium isotope Rb was developed for operation in space. The instrument design implements both and mode…”
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Miniature atomic scalar magnetometer for space based on the rubidium isotope 87Rb by Korth, Haje, Strohbehn, Kim, Tejada, Francisco, Andreou, Andreas G., Kitching, John, Knappe, Svenja, Lehtonen, S. John, London, Shaughn M., Kafel, Matiwos

“…A miniature atomic scalar magnetometer based on the rubidium isotope 87Rb was developed for operation in space. The instrument design implements both Mx and Mz…”
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Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13 by Nurmenniemi, S., Kuvaja, P., Lehtonen, S., Tiuraniemi, S., Alahuhta, I., Mattila, R.K., Risteli, J., Salo, T., Selander, K.S., Nyberg, P., Lehenkari, P.

“…Human mesenchymal stem cells (hMSCs) are multipotent cells that are found in the bone marrow. Inflammation and tissue damage mobilize MSCs and induce their…”
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Estrogen receptor alpha gene Xba I polymorphism in human mesenchymal stem cells influences osteoblast differentiation, activation and the effect of estrogen by Leskelä, H.-V, Lehtonen, S, Lehenkari, P

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Tumor tissue inhibitor of metalloproteinases-1 (TIMP-1) in hormone-independent breast cancer might originate in stromal cells, and improves stratification of prognosis together with nodal status by Kuvaja, P., Hulkkonen, S., Pasanen, I., Soini, Y., Lehtonen, S., Talvensaari-Mattila, A., Pääkkö, P., Kaakinen, M., Autio-Harmainen, H., Hurskainen, T., Lehenkari, P., Turpeenniemi-Hujanen, T.

“…Tissue inhibitor of metalloproteinases-1 (TIMP-1) is shown to be a potential marker for poor prognosis in breast cancer, but the biology of TIMP-1 is only…”
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INPPL1 is associated with the metabolic syndrome in men with Type 1 diabetes, but not with diabetic nephropathy by Hyvönen, M. E., Ihalmo, P., Forsblom, C., Thorn, L., Sandholm, N., Lehtonen, S., Groop, P.-H.

“…Diabet. Med. 29, 1589–1595 (2012) Aims  The metabolic syndrome is a frequent phenomenon in people with Type 1 diabetes and is associated with diabetic…”
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Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF- B and silenced by DNA methylation by Ristola, M., Arpiainen, S., Saleem, M. A., Holthofer, H., Lehtonen, S.

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P.186 Molecular pathways underlying schizophrenia by Tiihonen, J., Koskuvi, M., Lähteenvuo, M., Trontti, K., Ojansuu, I., Vaurio, O., Cannon, T.D., Lönnqvist, J., Therman, S., Suvisaari, J., Cheng, L., Tanskanen, A., Taipale, H., Lehtonen, Š., Koistinaho, J.

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Successful use of granulation tissue as therapeutic reagent in bone repair — Indications for use of 2-phase surgery in other regenerative applications by Aho, O.-M.J, Ristiniemi, J, Lehtonen, S, Lehenkari, P, Leskelä, H.-V

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3.142 CAENORHABDITIS ELEGANS AS A MODEL SYSTEM OF PARKINSON DISEASE FOR HIGH-CONTENT SCREENING by Lehtonen, S, Oksanen, M, Lakso, M, Wong, G, Courtney, M, Koistinaho, J

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Cell specific expression of peroxiredoxins in human lung and pulmonary sarcoidosis by Kinnula, V L, Lehtonen, S, Kaarteenaho-Wiik, R, Lakari, E, Pääkkö, P, Kang, S W, Rhee, S G, Soini, Y

“…Background: Six proteins of the peroxiredoxin (Prx) family have recently been characterised which have the capacity to decompose hydrogen peroxide in vivo and…”
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Neuropsychological outcome and community re-integration following traumatic brain injury: The impact of frontal and non-frontal lesions by Lehtonen, S., Stringer, A. Y., Millis, S., Boake, C., Englander, J., Hart, T., High, W., Macciocchi, S., Meythaler, J., Novack, T., Whyte, J.

“…Primary objective: To examine the relationship between cortical lesion location and brain injury outcome. It was hypothesized that focal frontal lesions after…”
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