Search Results - "Lehtinen, Markus J."

Role of Probiotics in Stimulating the Immune System in Viral Respiratory Tract Infections: A Narrative Review by Lehtoranta, Liisa, Latvala, Sinikka, Lehtinen, Markus J

“…Viral respiratory tract infection (RTI) is the most frequent cause of infectious illnesses including the common cold. Pharmacological solutions for treating or…”
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Gut Microbiota, Probiotics and Physical Performance in Athletes and Physically Active Individuals by Marttinen, Maija, Ala-Jaakkola, Reeta, Laitila, Arja, Lehtinen, Markus J

“…Among athletes, nutrition plays a key role, supporting training, performance, and post-exercise recovery. Research has primarily focused on the effects of diet…”
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Xylitol's Health Benefits beyond Dental Health: A Comprehensive Review by Salli, Krista, Lehtinen, Markus J, Tiihonen, Kirsti, Ouwehand, Arthur C

“…Xylitol has been widely documented to have dental health benefits, such as reducing the risk for dental caries. Here we report on other health benefits that…”
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Strain specific stress-modulating effects of candidate probiotics: A systematic screening in a mouse model of chronic restraint stress by Stenman, Lotta K., Patterson, Elaine, Meunier, Johann, Roman, Francois J., Lehtinen, Markus J.

“…•The impact of probiotics on gut-brain-axis signaling is species- and strain-specific.•Chronic restraint is a suitable model for detecting efficacy of…”
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Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement by Kajander, Tommi, Lehtinen, Markus J, Hyvärinen, Satu, Bhattacharjee, Arnab, Leung, Elisa, Isenman, David E, Meri, Seppo, Goldman, Adrian, Jokiranta, T. Sakari

“…The alternative pathway of complement is important in innate immunity, attacking not only microbes but all unprotected biological surfaces through powerful…”
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Bifidobacterium animalis subsp. lactis 420 for Metabolic Health: Review of the Research by Uusitupa, Henna-Maria, Rasinkangas, Pia, Lehtinen, Markus J, Mäkelä, Sanna M, Airaksinen, Kaisa, Anglenius, Heli, Ouwehand, Arthur C, Maukonen, Johanna

“…The growing worldwide epidemic of obesity and associated metabolic health comorbidities has resulted in an urgent need for safe and efficient nutritional…”
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Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge by Lehtinen, Markus J., Hibberd, Ashley A., Männikkö, Sofia, Yeung, Nicolas, Kauko, Tommi, Forssten, Sofia, Lehtoranta, Liisa, Lahtinen, Sampo J., Stahl, Buffy, Lyra, Anna, Turner, Ronald B.

“…The role of nasal and fecal microbiota in viral respiratory infections has not been established. We collected nasal swabs and washes, and fecal samples in a…”
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The Effect of Bifidobacterium animalis ssp. lactis HN019 on Cellular Immune Function in Healthy Elderly Subjects: Systematic Review and Meta-Analysis by Miller, Larry E, Lehtoranta, Liisa, Lehtinen, Markus J

“…Elderly people have increased susceptibility to infections and cancer that are associated with decline in cellular immune function. The objective of this work…”
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Enhancing Bioaccessibility of Plant Protein Using Probiotics: An In Vitro Study by Marttinen, Maija, Anjum, Mehreen, Saarinen, Markku T, Ahonen, Ilmari, Lehtinen, Markus J, Nurminen, Päivi, Laitila, Arja

“…As plant-based diets become more popular, there is an interest in developing innovations to improve the bioaccessibility of plant protein. In this study, seven…”
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Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation by Deban, Livija, Jarva, Hanna, Lehtinen, Markus J, Bottazzi, Barbara, Bastone, Antonio, Doni, Andrea, Jokiranta, T. Sakari, Mantovani, Alberto, Meri, Seppo

“…The long pentraxin PTX3 is a multifunctional soluble molecule involved in inflammation and innate immunity. As an acute phase protein, PTX3 binds to the…”
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Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial by Stenman, Lotta K., Lehtinen, Markus J., Meland, Nils, Christensen, Jeffrey E., Yeung, Nicolas, Saarinen, Markku T., Courtney, Michael, Burcelin, Rémy, Lähdeaho, Marja-Leena, Linros, Jüri, Apter, Dan, Scheinin, Mika, Kloster Smerud, Hilde, Rissanen, Aila, Lahtinen, Sampo

“…The gut microbiota is interlinked with obesity, but direct evidence of effects of its modulation on body fat mass is still scarce. We investigated the possible…”
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Lactobacillus acidophilus NCFM and Lactiplantibacillus plantarum Lp-115 inhibit Helicobacter pylori colonization and gastric inflammation in a murine model by Shen, Siqi, Ren, FeiFei, Qin, Haiming, Bukhari, Ihtisham, Yang, Jing, Gao, Dafang, Ouwehand, Arthur C, Lehtinen, Markus J, Zheng, Pengyuan, Mi, Yang

“…To determine the role of Lactobacillus strains and their combinations in inhibiting the colonization of and gastric mucosa inflammation. Human gastric…”
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Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein by Laine, Matti, Jarva, Hanna, Seitsonen, Sanna, Haapasalo, Karita, Lehtinen, Markus J, Lindeman, Nina, Anderson, Don H, Johnson, Patrick T, Jarvela, Irma, Jokiranta, T. Sakari, Hageman, Gregory S, Immonen, Ilkka, Meri, Seppo

“…Complement factor H (FH) is an important regulator of the alternative complement pathway. The Y402H polymorphism within the seventh short consensus repeat of…”
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T-bet+ Memory B Cells Link to Local Cross-Reactive IgG upon Human Rhinovirus Infection by Eccles, Jacob D., Turner, Ronald B., Kirk, Nicole A., Muehling, Lyndsey M., Borish, Larry, Steinke, John W., Payne, Spencer C., Wright, Paul W., Thacker, Deborah, Lahtinen, Sampo J., Lehtinen, Markus J., Heymann, Peter W., Woodfolk, Judith A.

“…Human rhinoviruses cause the common cold and exacerbate chronic respiratory diseases. Although infection elicits neutralizing antibodies, these do not persist…”
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The effect of an apple polyphenol extract rich in epicatechin and flavan-3-ol oligomers on brachial artery flow-mediated vasodilatory function in volunteers with elevated blood pressure by Saarenhovi, Maria, Salo, Pia, Scheinin, Mika, Lehto, Jussi, Lovró, Zsófia, Tiihonen, Kirsti, Lehtinen, Markus J, Junnila, Jouni, Hasselwander, Oliver, Tarpila, Anneli, Raitakari, Olli T

“…The primary aim of this study was to test the hypothesis that an orally ingested apple polyphenol extract rich in epicatechin and flavan-3-ol oligomers…”
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Mutations of Factor H Impair Regulation of Surface-bound C3b by Three Mechanisms in Atypical Hemolytic Uremic Syndrome by Lehtinen, Markus J., Rops, Angelique L., Isenman, David E., van der Vlag, Johan, Jokiranta, T. Sakari

“…Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy associated with mutations in complement proteins, most frequently in the main plasma…”
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The effect of probiotic Bifidobacterium lactis Bl-04 on innate antiviral responses in vitro by Latvala, Sinikka, Lehtinen, Markus J, Mäkelä, Sanna M, Nedveck, Derek, Zabel, Bryan, Ahonen, Ilmari, Lehtoranta, Liisa, Turner, Ronald B, Liljavirta, Jenni

“…Consumption of certain probiotic strains may be beneficial for reducing the risk of acute upper respiratory tract infections (URTIs), however, underlying…”
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Interactions between the human milk oligosaccharide 2′-fucosyllactose and Bifidobacterium longum subspecies infantis in influencing systemic immune development and function in piglets by Daniels, Victoria C., Monaco, Marcia H., Hirvonen, Johanna, Ouwehand, Arthur C., Jensen, Henrik Max, Mukerjea, Ratna, Christensen, Niels, Lehtinen, Markus J., Dilger, Ryan N., Donovan, Sharon M.

“…Introduction The oligosaccharide 2′-fucosyllactose (2′-FL) is a predominant component of human milk, serving as a prebiotic for gut microbiota and influencing…”
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The Effect of Bifidobacterium animalis subsp. lactis Bl-04 on Influenza A Virus Infection in Mice by Zabel, Bryan, Mäkelä, Sanna M., Nedveck, Derek, Hibberd, Ashley A., Yeung, Nicolas, Latvala, Sinikka, Lehtoranta, Liisa, Junnila, Jouni, Walters, Kevin B., Morovic, Wesley, Lehtinen, Markus J.

“…Influenza A virus infection is a major global disease requiring annual vaccination. Clinical studies indicate that certain probiotics may support immune…”
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The effect of the probiotic consortia on SARS-CoV-2 infection in ferrets and on human immune cell response in vitro by Lehtinen, Markus J., Kumar, Ritesh, Zabel, Bryan, Mäkelä, Sanna M., Nedveck, Derek, Tang, Peipei, Latvala, Sinikka, Guery, Sebastien, Budinoff, Charles R.

“…Probiotics have been suggested as one solution to counter detrimental health effects by SARS-CoV-2; however, data so far is scarce. We tested the effect of two…”
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