Linguistic and psychometric validation of the MSSS-88 questionnaire for patients with multiple sclerosis and spasticity in Germany

Linguistic and psychometric validation of the MSSS-88 questionnaire for patients with multiple sclerosis and spasticity in Germany

Multiple sclerosis (MS) is an inflammatory disease where many of the patients suffer from spasticity impacting their quality-of-life. The purpose of this paper was to linguistically validate and psychometrically test the Multiple Sclerosis Spasticity Scale (MSSS-88) in German speaking MS patients. T...

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Bibliographic Details
Published in:Health and quality of life outcomes Vol. 12; no. 1; p. 119
Main Authors: Henze, Thomas, von Mackensen, Sylvia, Lehrieder, Gerald, Zettl, Uwe K, Pfiffner, Carmen, Flachenecker, Peter
Format: Journal Article
Language:English
Published: England BioMed Central Ltd 01-08-2014
BioMed Central
Subjects:
Activities of daily living
Adult
Aged
Care and treatment
Colleges & universities
Complications and side effects
Culture
Data entry
Diagnosis
Female
Germany
Humans
Information management
Linguistics
Male
Medical treatment
Middle Aged
Multiple sclerosis
Multiple Sclerosis - complications
Muscle pain
Muscle Spasticity - diagnosis
Muscle Spasticity - etiology
Neurology
Patient Outcome Assessment
Patients
Prospective Studies
Psychometrics
Quality of Life
Questionnaires
Rehabilitation
Reproducibility of Results
Risk factors
Severity of Illness Index
Spasticity
Surveys and Questionnaires
Translating and interpreting
Translations
Validation studies
Germany
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Summary:Multiple sclerosis (MS) is an inflammatory disease where many of the patients suffer from spasticity impacting their quality-of-life. The purpose of this paper was to linguistically validate and psychometrically test the Multiple Sclerosis Spasticity Scale (MSSS-88) in German speaking MS patients. The study had two stages: 1) forward/backward translations of the original MSSS-88 scale into German, discussions with MS-experts and cognitive debriefings with MS patients; 2) psychometric evaluation of the German version. Data collection took part in an observational multi-centre study in Germany (MOVE2). The German translation of the MSSS-88 scale was discussed with three MS-experts; followed by two cognitive debriefing sessions with 12 MS patients. For psychometric evaluation the MSSS-88 was filled in by 87 MS patients with a mean age of 50.2 ± 10.4 years; 26.4% of them had severe spasticity. Data quality was acceptable. Missing data for items of the MSSS-88 were low (range 0-5.75%). Psychometric testing of the MSSS-88 revealed excellent values for reliability and validity. Significant differences between groups regarding severity, grading, type and self-ratings of MS-spasticity and sleep disturbances were found. Sensitivity to change could be demonstrated for the MSSS-88 in the group of MS patients treated with cannabinoid oromucosal spray vs. non-treated patients. In the treated group significant changes with a moderate effect size were found for 'muscle spasms', 'emotional health' and 'pain/discomfort'. No significant changes could be detected in the non-treated group. Preliminary evidence from this small study supports reliability, validity, and responsiveness of the German version of the MSSS-88 for measuring the impact of spasticity in MS.
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ISSN:1477-7525
1477-7525
DOI:10.1186/s12955-014-0119-y