Search Results - "Lehoux, Sylvain D."
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Glycosylation of Zika Virus is Important in Host-Virus Interaction and Pathogenic Potential
Published in International journal of molecular sciences (21-10-2019)“…Zika virus (ZIKV) is a global public health issue due to its association with severe developmental disorders in infants and neurological disorders in adults…”
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PDX-derived organoids model in vivo drug response and secrete biomarkers
Published in JCI insight (05-11-2020)“…Patient-derived organoid models are proving to be a powerful platform for both basic and translational studies. Here we conduct a methodical analysis of…”
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ST6Gal1 in plasma is dispensable for IgG sialylation
Published in Glycobiology (Oxford) (18-08-2022)“…Abstract The glycosylation of immunoglobulin G (IgG) has attracted increased attention due to the impact of N-glycan modifications at N297 on IgG function,…”
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Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers
Published in Proteomics. Clinical applications (01-10-2013)“…In many different human disorders, the cellular glycome is altered. An interesting but poorly understood alteration occurs in the mucin‐type O‐glycome, in…”
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Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N‐Glycosylation in Antibody‐Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren’s Syndrome
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2018)“…Objective To better understand the role of B cells, the potential mechanisms responsible for their aberrant activation, and the production of autoantibodies in…”
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Cosmc Is Silenced in Human Tn4 B Cells through Hypermethylation of the Gene Promoter
Published in The FASEB journal (01-04-2012)“…Abstract only Background Mucin‐type O‐glycosylation is regulated through core 1 β3‐galatosyltransferase (T‐synthase) and its specific molecular chaperone…”
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T n and sialyl‐Tn antigens, aberrant O ‐glycomics as human disease markers
Published in Proteomics. Clinical applications (01-10-2013)“…In many different human disorders, the cellular glycome is altered. An interesting but poorly understood alteration occurs in the mucin‐type O ‐glycome, in…”
Get full text
Journal Article