Search Results - "Lehoux, Jordan"
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Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor
Published in International journal of molecular sciences (12-09-2021)“…Follicle-stimulating hormone receptor (FSHR) plays a key role in reproduction through the activation of multiple signaling pathways. Low molecular weight (LMW)…”
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Overview of alkyl quercetin lipophenol synthesis and its protective effect against carbonyl stress involved in neurodegeneration
Published in Organic & biomolecular chemistry (03-04-2024)“…Oxidative stress and carbonyl stress resulting from the toxicity of small aldehydes are part of the detrimental mechanisms leading to neuronal cell loss…”
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Synthesis of Fatty Acid Bioconjugates and Related Derivatives
Published in European journal of organic chemistry (07-06-2022)“…Several families of naturally occurring fatty acid conjugates are presented. Chemical and chemoenzymatic syntheses are exemplified for fatty acid conjugates…”
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A novel lipophenol quercetin derivative to prevent macular degeneration: Intravenous and oral formulations for preclinical pharmacological evaluation
Published in International journal of pharmaceutics (15-02-2024)“…[Display omitted] Drugs with properties against oxidative and carbonyl stresses are potential candidates to prevent dry age-related macular degeneration…”
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Hydroxytyrosol fatty acid esters as new candidate markers for detecting olive oil inadequate storage conditions by UHPLC-QqQ-MS/MS
Published in Microchemical journal (01-10-2022)“…[Display omitted] •Increase of HT and HT-FAs in EVOO after storage for 12 months.•The rate of increase of HT-FAs was greater at high temperature (40 °C) than…”
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