Search Results - "Lehotay, D C"

Development of morphologically dominant follicles is associated with fewer metabolic disturbances in amenorrheic women with polycystic ovary syndrome: a pilot study by Lujan, M. E., Kepley, A. L., Chizen, D. R., Lehotay, D. C., Pierson, R. A.

“…Objectives To determine if amenorrheic women with polycystic ovary syndrome (PCOS) demonstrate ultrasonographically detectable changes in follicle population…”
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Simple method for the quantitative analysis of endogenous folate catabolites p-aminobenzoylglutamate (pABG) and its acetamido (apABG) derivative in human serum and urine by liquid chromatography-tandem mass spectrometry by Sokoro, A.A.H., Etter, M.L., Lepage, J., Weist, B., Eichhorst, J., Lehotay, D.C.

“…To develop a routine method for quantitative measurement of the folate catabolites p-aminobenzoylglutamate (pABG) and acetamidobenzoylglutamate (apABG) in…”
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Ruptured abdominal aortic aneurysm, a “two-hit” ischemia/reperfusion injury: Evidence from an analysis of oxidative products by Lindsay, Thomas F., Luo, Xao P., Lehotay, Denis C., Rubin, Barry B., Anderson, Michael, Walker, Paul M., Romaschin, Alex D.

“…Purpose: Ruptured abdominal aortic aneurysm (RAAA) remains a lethal condition despite improvements in perioperative care. The consequences of RAAA are…”
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Hyperornithinemia‐Hyperammonemia‐Homocitrullinuria Syndrome (HHH) Presenting With Acute Fulminant Hepatic Failure by Mhanni, AA, Chan, A, Collison, M, Seifert, B, Lehotay, DC, Sokoro, AH, Huynh, HQ, Greenberg, CR

“…ABSTRACT We report on two Aboriginal patients with the hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome. Both presented with acute hepatic…”
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LC–MS/MS progress in newborn screening by Lehotay, D.C., Hall, P., Lepage, J., Eichhorst, J.C., Etter, M.L., Greenberg, C.R.

“…Newborn screening programs detect treatable disorders in infants before they become symptomatic. Liquid chromatography-tandem mass spectrometry (LC–MS/MS) has…”
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Blood acylcarnitine levels in normal newborns and heterozygotes for medium‐chain acyl‐CoA dehydrogenase deficiency: A relationship between genotype and biochemical phenotype? by Lehotay, D. C., LePage, J., Thompson, J. R., Rockman‐Greenberg, C.

“…Patients with medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency are unable to metabolize medium‐chain fatty acids. Affected patients display a…”
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Determination of Aldehydes and Other Lipid Peroxidation Products in Biological Samples by Gas Chromatography-Mass Spectrometry by Luo, X.P., Yazdanpanah, M., Bhooi, N., Lehotay, D.C.

“…The extremely broad spectrum of the biological effects of aldehydic lipid peroxidation products has necessitated the development of a technique that can…”
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Determination of free and protein-bound methadone and its major metabolite EDDP: Enantiomeric separation and quantitation by LC/MS/MS by Etter, M.L., George, S., Graybiel, K., Eichhorst, J., Lehotay, D.C.

“…To measure free and protein-bound R- and S-enantiomers of methadone and its major metabolite, 2-ethylidine-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) in…”
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Diabetic nephropathy in hypertransfused patients with beta-thalassemia. The role of oxidative stress by LOEBSTEIN, R, LEHOTAY, D. C, XIAOPING LUO, BARTFAY, W, TYLER, B, SHER, G. D

“…Diabetic nephropathy in hypertransfused patients with beta-thalassemia. The role of oxidative stress. R Loebstein , D C Lehotay , X Luo , W Bartfay , B Tyler…”
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Urinary screening for methylphenidate (Ritalin) abuse: a comparison of liquid chromatography–tandem mass spectrometry, gas chromatography–mass spectrometry, and immunoassay methods by Eichhorst, J, Etter, M, Lepage, J, Lehotay, D.C

“…Objective: To develop a routine method for detecting methylphenidate (Ritalin) use among drug abusers using liquid chromatography–tandem mass spectrometry…”
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Free and bound enantiomers of methadone and its metabolite, EDDP in methadone maintenance treatment: Relationship to dosage? by Lehotay, D.C., George, S., Etter, M.L., Graybiel, K., Eichhorst, J.C., Fern, B., Wildenboer, W., Selby, P., Kapur, B.

“…To determine the effects of metabolism and protein binding on the relationship between administered dose, blood levels of R methadone and biological response…”
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Cardiac function and cytotoxic aldehyde production in a murine model of chronic iron-overload by BARTFAY, W. J, DAWOOD, F, WEN, W. H, LEHOTAY, D. C, HOU, D, BARTFAY, E, XIAOPING LUO, BACKX, P. H, LIU, P. P

“…To determine the relationship between the total chronic dose of iron administered, ex-vivo cardiac function and the concentrations of cytotoxic aldehydes in…”
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Simplified simultaneous assay of total plasma homocysteine and methionine by HPLC and pulsed integrated amperometry by Cole, D E, Lehotay, D C, Evrovski, J

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Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism by Nowaczyk, Malgorzata J.M., Lehotay, Denis C., Platt, B.-A., Fisher, Larry, Tan, Rosemary, Phillips, Helen, Clarke, J.T.R.

“…Ethylmalonic encephalopathy (EE), an organic aciduria of unknown etiology characterized by developmental delay, hypotonia, and vascular instability associated…”
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“Hypotyrosinemia” in Phenylketonuria by Hanley, W.B., Lee, A.W., Hanley, A.J.G., Lehotay, D.C., Austin, V.J., Schoonheyt, W.E., Platt, B.A., Clarke, J.T.R.

“…It has been postulated that the significant incidence of learning disabilities in well-treated patients with phenylketonuria (PKU) may be due, in part, to…”
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Cytotoxic aldehyde generation in heart following acute iron-loading by Bartfay, W.J., Hou, D., Lehotay, D.C., Luo, X., Bartfay, E., Backx, P.H., Liu, P.P.

“…Although the mechanism of myocardial failure following acute iron poisoning is not known, excess iron-catalyzed free radical generation is conjectured to play…”
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Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria by Smith, Mary Lou, Hanley, William B, Clarke, Joe T R, Klim, Paula, Schoonheyt, Wanda, Austin, Valerie, Lehotay, Denis C

“…OBJECTIVE To test the efficacy of tyrosine supplementation, as an adjunct to dietary treatment, on neuropsychological test performance in individuals with…”
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Fatty acid oxidation abnormalities in childhood-onset spinal muscular atrophy: Primary or secondary defect(s)? by Tein, Ingrid, Sloane, Avril E., Donner, Elizabeth J., Lehotay, Dennis C., Millington, David S., Kelley, Richard I.

“…The purpose of this study was to further identify and quantify the fatty acid oxidation abnormalities in spinal muscular atrophy, correlate these with disease…”
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Feto-maternal plasma phenylalanine concentration gradient from 19 weeks gestation to term by Schoonheyt, W E, Clarke, J T, Hanley, W B, Johnson, J M, Lehotay, D C

“…Plasma phenylalanine concentrations in fetal blood, obtained by cordocentesis, were compared with simultaneous peripheral venous plasma phenylalanine levels in…”
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Effect of transfusion on lipid peroxidation products in the plasma of thalassemic patients by Sher, G D, Bartfay, W J, Liu, P P, Lehotay, D C

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