Search Results - "Lehner, F"

Dispersive forces and resisting spot welds by alternative homolog conjunction govern chromosome shape in Drosophila spermatocytes during prophase I by Vernizzi, Luisa, Lehner, Christian F

“…The bivalent chromosomes that are generated during prophase of meiosis I comprise a pair of homologous chromosomes. Homolog pairing during prophase I must…”
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Bivalent individualization during chromosome territory formation in Drosophila spermatocytes by controlled condensin II protein activity and additional force generators by Vernizzi, Luisa, Lehner, Christian F

“…Reduction of genome ploidy from diploid to haploid necessitates stable pairing of homologous chromosomes into bivalents before the start of the first meiotic…”
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Insights from Earth system model initial-condition large ensembles and future prospects by Deser, C., Lehner, F., Rodgers, K. B., Ault, T., Delworth, T. L., DiNezio, P. N., Fiore, A., Frankignoul, C., Fyfe, J. C., Horton, D. E., Kay, J. E., Knutti, R., Lovenduski, N. S., Marotzke, J., McKinnon, K. A., Minobe, S., Randerson, J., Screen, J. A., Simpson, I. R., Ting, M.

“…Internal variability in the climate system confounds assessment of human-induced climate change and imposes irreducible limits on the accuracy of climate…”
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Teflon promotes chromosomal recruitment of homolog conjunction proteins during Drosophila male meiosis by Kabakci, Zeynep, Yamada, Hiro, Vernizzi, Luisa, Gupta, Samir, Weber, Joe, Sun, Michael Shoujie, Lehner, Christian F

“…Meiosis in males of higher dipterans is achiasmate. In their spermatocytes, pairing of homologs into bivalent chromosomes does not include synaptonemal complex…”
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Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin by Kabakci, Zeynep, Reichle, Heidi E, Lemke, Bianca, Rousova, Dorota, Gupta, Samir, Weber, Joe, Schleiffer, Alexander, Weir, John R, Lehner, Christian F

“…For meiosis I, homologous chromosomes must be paired into bivalents. Maintenance of homolog conjunction in bivalents until anaphase I depends on crossovers in…”
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Storylines for unprecedented heatwaves based on ensemble boosting by Fischer, E. M., Beyerle, U., Bloin-Wibe, L., Gessner, C., Humphrey, V., Lehner, F., Pendergrass, A. G., Sippel, S., Zeder, J., Knutti, R.

“…Recent temperature extremes have shattered previously observed records, reaching intensities that were inconceivable before the events. Could the possibility…”
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Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis by Klein, Sebastian J., Brandtner, Anna K., Lehner, Georg F., Ulmer, Hanno, Bagshaw, Sean M., Wiedermann, Christian J., Joannidis, Michael

“…Purpose Acute kidney injury (AKI) frequently occurs in critically ill patients and often precipitates use of renal replacement therapy (RRT). However, the…”
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Dynamics and control of sister kinetochore behavior during the meiotic divisions in Drosophila spermatocytes by Chaurasia, Soumya, Lehner, Christian F

“…Sister kinetochores are connected to the same spindle pole during meiosis I and to opposite poles during meiosis II. The molecular mechanisms controlling the…”
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Impaired fibrinolysis in critically ill COVID-19 patients by Bachler, Mirjam, Bösch, Johannes, Stürzel, Daniel P, Hell, Tobias, Giebl, Andreas, Ströhle, Mathias, Klein, Sebastian J, Schäfer, Volker, Lehner, Georg F, Joannidis, Michael, Thomé, Claudius, Fries, Dietmar

“…Critically ill coronavirus disease 2019 (COVID-19) patients present with a hypercoagulable state with high rates of macrovascular and microvascular thrombosis,…”
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Nonlinear Response of Extreme Precipitation to Warming in CESM1 by Pendergrass, A. G., Coleman, D. B., Deser, C., Lehner, F., Rosenbloom, N., Simpson, I. R.

“…The response of extreme precipitation to warming varies widely among climate models, especially in the tropics. In some models, there have been indications…”
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Mass‐Conserving Downscaling of Climate Model Precipitation Over Mountainous Terrain for Water Resource Applications by Rugg, A., Gutmann, E. D., McCrary, R. R., Lehner, F., Newman, A. J., Richter, J. H., Tye, M. R., Wood, A. W.

“…A mass‐conserving method to downscale precipitation from global climate models (GCMs) using sub‐grid‐scale topography and modeled 700‐mb wind direction is…”
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Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid/Cenp-A presence in Drosophila sperm by Raychaudhuri, Nitika, Dubruille, Raphaelle, Orsi, Guillermo A, Bagheri, Homayoun C, Loppin, Benjamin, Lehner, Christian F

“…In Drosophila melanogaster, as in many animal and plant species, centromere identity is specified epigenetically. In proliferating cells, a centromere-specific…”
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Nuclear elongation during spermiogenesis depends on physical linkage of nuclear pore complexes to bundled microtubules by Drosophila Mst27D by Li, Pengfei, Messina, Giovanni, Lehner, Christian F

“…Spermatozoa in animal species are usually highly elongated cells with a long motile tail attached to a head that contains the haploid genome in a compact and…”
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Incorporation of Drosophila CID/CENP-A and CENP-C into Centromeres during Early Embryonic Anaphase by Schuh, Melina, Lehner, Christian F., Heidmann, Stefan

“…The centromere/kinetochore complex is indispensable for accurate segregation of chromosomes during cell divisions when it serves as the attachment site for…”
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Five‐Year Outcomes in Kidney Transplant Patients Converted From Cyclosporine to Everolimus: The Randomized ZEUS Study by Budde, K., Lehner, F., Sommerer, C., Reinke, P., Arns, W., Eisenberger, U., Wüthrich, R. P., Mühlfeld, A., Heller, K., Porstner, M., Veit, J., Paulus, E.‐M., Witzke, O.

“…ZEUS study was an open‐label, 12‐month, multicenter study in which 300 de novo kidney transplant recipients were randomized to continue receiving cyclosporine…”
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Repeat liver resection for colorectal metastases by Kulik, U., Bektas, H., Klempnauer, J., Lehner, F.

“…Background Following resection of colorectal liver metastases (CLMs) up to 75 per cent of patients develop recurrent liver metastases. Although repeat…”
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Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO by Weber, Joe, Kabakci, Zeynep, Chaurasia, Soumya, Brunner, Erich, Lehner, Christian F

“…Regular chromosome segregation during the first meiotic division requires prior pairing of homologous chromosomes into bivalents. During canonical meiosis,…”
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MNM and SNM maintain but do not establish achiasmate homolog conjunction during Drosophila male meiosis by Sun, Michael Shoujie, Weber, Joe, Blattner, Ariane C, Chaurasia, Soumya, Lehner, Christian F

“…The first meiotic division reduces genome ploidy. This requires pairing of homologous chromosomes into bivalents that can be bi-oriented within the spindle…”
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Linkage of alterations in systemic iron homeostasis to patients' outcome in sepsis: a prospective study by Brandtner, Anna, Tymoszuk, Piotr, Nairz, Manfred, Lehner, Georg F, Fritsche, Gernot, Vales, Anja, Falkner, Andreas, Schennach, Harald, Theurl, Igor, Joannidis, Michael, Weiss, Günter, Pfeifhofer-Obermair, Christa

“…Sepsis, a dysregulated host response following infection, is associated with massive immune activation and high mortality rates. There is still a need to…”
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A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells by Bai, Yu, Caussinus, Emmanuel, Leo, Stefano, Bosshardt, Fritz, Myachina, Faina, Rot, Gregor, Robinson, Mark D, Lehner, Christian F

“…Temperature change affects the myriad of concurrent cellular processes in a non-uniform, disruptive manner. While endothermic organisms minimize the challenge…”
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