Search Results - "Lehnen, Harald"

Epigenetics and life-long consequences of an adverse nutritional and diabetic intrauterine environment by El Hajj, Nady, Schneider, Eberhard, Lehnen, Harald, Haaf, Thomas

“…The phenomenon that adverse environmental exposures in early life are associated with increased susceptibilities for many adult, particularly metabolic…”
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Metabolic Programming of MEST DNA Methylation by Intrauterine Exposure to Gestational Diabetes Mellitus by NADY EL HAJJ, PLIUSHCH, Galyna, SCHNEIDER, Eberhard, DITTRICH, Marcus, MÜLLER, Tobias, KORENKOV, Michael, ARETZ, Melanie, ZECHNER, Ulrich, LEHNEN, Harald, HAAF, Thomas

“…Epigenetic processes are primary candidates when searching for mechanisms that can stably modulate gene expression and metabolic pathways according to early…”
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Epigenetic signatures of gestational diabetes mellitus on cord blood methylation by Haertle, Larissa, El Hajj, Nady, Dittrich, Marcus, Müller, Tobias, Nanda, Indrajit, Lehnen, Harald, Haaf, Thomas

“…Intrauterine exposure to gestational diabetes mellitus (GDM) confers a lifelong increased risk for metabolic and other complex disorders to the offspring…”
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Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals by Haertle, Larissa, Maierhofer, Anna, Böck, Julia, Lehnen, Harald, Böttcher, Yvonne, Blüher, Matthias, Schorsch, Martin, Potabattula, Ramya, El Hajj, Nady, Appenzeller, Silke, Haaf, Thomas

“…Imprinted genes show parent-specific activity (functional haploidy), which makes them particularly vulnerable to epigenetic dysregulation. Here we studied the…”
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Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life by Lehnen, Harald, Zechner, Ulrich, Haaf, Thomas

“…The epidemic increase of type 2 diabetes and obesity in developed countries cannot be explained by overnutrition, physical inactivity and/or genetic factors…”
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DNA methylation signatures in cord blood of ICSI children by El Hajj, Nady, Haertle, Larissa, Dittrich, Marcus, Denk, Sarah, Lehnen, Harald, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas

“…Abstract STUDY QUESTION Does ICSI induce specific DNA methylation changes in the resulting offspring? SUMMARY ANSWER Although several thousand analyzed CpG…”
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Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life by Lehnen, H., Zechner, U., Haaf, T.

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The Impact of Insulin Treatment on the Expression of Vascular Endothelial Cadherin and Beta-Catenin in Human Fetoplacental Vessels by Baumüller, Samira, Lehnen, Harald, Schmitz, Jörg, Fimmers, Rolf, Müller, Annette M.

“…Vascular endothelial cadherin and β-catenin play a key role in establishment and maintenance of the endothelial monolayer integrity, regulation of vascular…”
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