Search Results - "Lehmann, W. D."

Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach by nanoelectrospray-tandem mass spectrometry by Ehehalt, R., Wagenblast, J., Erben, G., Lehmann, W.-D., Hinz, U., Merle, U., Stremmel, W.

“…Background: A defective mucus composition represents a key pathogenetic factor for intestinal injury. Phosphatidylcholine (PC) is an essential component…”
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Quantitative Analysis of Biological Membrane Lipids at the Low Picomole Level by Nano-Electrospray Ionization Tandem Mass Spectrometry by Brugger, B., Erben, G., Sandhoff, R., Wieland, F. T., Lehmann, W. D.

“…Nano-electrospray tandem mass spectrometry allows qualitative and quantitative analysis of complex membrane lipid mixtures at the subpicomole level. We have…”
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Lipid Patches in Membrane Protein Oligomers: Crystal Structure of the Bacteriorhodopsin-Lipid Complex by L.-O. Essen, Siegert, R., Lehmann, W. D., Oesterhelt, D.

“…Heterogenous nucleation on small molecule crystals causes a monoclinic crystal form of bacteriorhodopsin (BR) in which trimers of this membrane protein pack…”
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Protein Phosphorylation Degree:  Determination by Capillary Liquid Chromatography and Inductively Coupled Plasma Mass Spectrometry by Wind, Mathias, Wesch, Horst, Lehmann, Wolf D

“…Capillary liquid chromatography (μLC) interfaced to inductively coupled plasma mass spectrometry (ICPMS) is introduced as a new micromethod to determine the…”
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Analysis of Protein Phosphorylation by a Combination of Elastase Digestion and Neutral Loss Tandem Mass Spectrometry by Schlosser, Andreas, Pipkorn, Ruediger, Bossemeyer, Dirk, Lehmann, Wolf D

“…Loss of phosphoric acid is the most effective fragmentation reaction of pSer- and pThr-containing phosphopeptides of small size (up to 10−15 residues) in…”
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Electrospray tandem mass spectrometric studies of phosphopeptides and phosphopeptide analogues by Tholey, Andreas, Reed, Jennifer, Lehmann, Wolf D.

“…A set of synthetic phosphopeptides and phosphopeptide analogues was studied by tandem nano‐electrospray mass spectrometry. The influence of the collision…”
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Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione by BARNOUIN, K, LEIER, I, JEDLITSCHKY, G, POURTIER-MANZANEDO, A, KÖNIG, J, LEHMANN, W.-D, KEPPLER, D

“…The human multidrug resistance protein (MRP1) confers resistance of cells to a number of different cytostatic drugs and functions as an export pump for…”
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Arachidonic Acid Metabolism in Primary Irritant Dermatitis Produced by Patch Testing of Human Skin with Surfactants by Müller-Decker, K., Heinzelmann, T., Fürstenberger, G., Kecskes, A., Lehmann, W.-D., Marks, F.

“…A clinical study was performed to determine the effects of patch testing human skin with four industrially used surfactants on erythema formation,…”
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Analysis of isoaspartate in peptides by electrospray tandem mass spectrometry by LEHMANN, WOLF D., SCHLOSSER, ANDREAS, ERBEN, GERHARD, PIPKORN, RÜDIGER, BOSSEMEYER, DIRK, KINZEL, VOLKER

“…In view of the significance of Asn deamidation and Asp isomerization to isoAsp at certain sites for protein aging and turnover, it was desirable to challenge…”
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Radioiodinated N-(2-Diethylaminoethyl)benzamide Derivatives with High Melanoma Uptake:  Structure−Affinity Relationships, Metabolic Fate, and Intracellular Localization by Eisenhut, Michael, Hull, William E, Mohammed, Ashour, Mier, Walter, Lay, Dorothee, Just, Wilhelm, Gorgas, Karin, Lehmann, Wolf D, Haberkorn, Uwe

“…Several radioiodinated N-(dialkylaminoalkyl)benzamides have been used for planar scintigraphy and single-photon emission computed tomography (SPECT) of…”
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Enzymic characterization of epidermis-derived 12-lipoxygenase isoenzymes by Siebert, M, Krieg, P, Lehmann, W D, Marks, F, Fürstenberger, G

“…Substrate selectivity and other enzymic characteristics of two epidermis-derived lipoxygenases (LOXs), the epidermis-type (e) (12S)-LOX and (12R)-LOX, were…”
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Detection of Modified Peptides in Enzymatic Digests by Capillary Liquid Chromatography/Electrospray Mass Spectrometry and a Programmable Skimmer CID Acquisition Routine by Jedrzejewski, Paul T, Lehmann, Wolf D

“…A method for the identification of multiple covalent protein modifications in enzymatic protein digests by specific marker ion signals in a single analysis is…”
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Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells by Eichhorn, T, Schloissnig, S, Hahn, B, Wendler, A, Mertens, Rolf, Lehmann, W D, Krauth-Siegel, R L, Efferth, T

“…Determining interacting cellular partners of drugs by chemical proteomic techniques is complex and tedious. Most approaches rely on activity-based probe…”
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Peroxisomal degradation of leukotrienes by beta-oxidation from the omega-end by JEDLITSCHKY, G, HUBER, M, VOLKL, A, MÜLLER, M, LEIER, I, MÜLLER, J, LEHMANN, W.-D, FAHIMI, H. D, KEPPLER, D

“…Chain shortening via beta-oxidation from the omega-end has been recognized as the major pathway for the degradation of cysteinyl leukotrienes as well as…”
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The amino terminus of PKA catalytic subunit— A site for introduction of posttranslational heterogeneities by deamidation: d-Asp2 and d-isoAsp2 containing isozymes by KINZEL, VOLKER, KÖNIG, NORBERT, PIPKORN, RÜDIGER, BOSSEMEYER, DIRK, LEHMANN, WOLF D.

“…Conserved deamidation of PKA catalytic subunit isozymes Cα and Cβ—more than 25% at Asn2 in vivo in both cases—has been shown to yield Asp2- and…”
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Defects in the synthesis of cysteinyl leukotrienes: A new group of inborn errors of metabolism by Mayatepek, E., Zelezny, R., Lehmann, W. D., Hammond, J. W., Hoffmann, G. F.

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Acute Hypoxia–Reperfusion Triggers Immunocompromise in Nile Tilapia by Choi, K., Lehmann, D. W., Harms, C. A., Law, J. M.

“…Inadequate dissolved oxygen in the aquatic environment is a well‐established cause of fish morbidity and mortality. The specific effects of hypoxia on immune…”
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Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry by Lehmann, W D, Stephan, M, Fürstenberger, G

“…A method for determination of the lipoxygenase products of linoleic acid (9- and 13-hydroxyoctadecadienoic acid; 9-HODE, 13-HODE) and of arachidonic acid (5-,…”
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Increased generation of cysteinyl leukotrienes in Kawasaki disease by Mayatepek, E, Lehmann, W D

“…Endogenous cysteinyl leukotriene synthesis was assessed in 10 patients with Kawasaki disease and 10 healthy controls by measuring excretion of leukotriene E4…”
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Bifunctional NHS-BAT Ester for Antibody Conjugation and Stable Technetium-99m Labeling: Conjugation Chemistry, Immunoreactivity and Kit Formulation by Eisenhut, M, Lehmann, W.D, Becker, W, Behr, T, Elser, H, Strittmatter, W, Steinstrasser, A, Baum, R.P, Valerius, T, Repp, R, Deo, Y

“…Conjugation chemistry and kit formulated binding of the NHS ester of 6-(4'-(4"-carboxyphenoxy)butyl)-2, 10-dimercapto-2,10-dimethyl-4,8-diazaundecane (NHS-BAT…”
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