Search Results - "Lehmann, Sabrina"

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis by Siffrin, Volker, Radbruch, Helena, Glumm, Robert, Niesner, Raluca, Paterka, Magdalena, Herz, Josephine, Leuenberger, Tina, Lehmann, Sabrina M., Luenstedt, Sarah, Rinnenthal, Jan Leo, Laube, Gregor, Luche, Hervé, Lehnardt, Seija, Fehling, Hans-Joerg, Griesbeck, Oliver, Zipp, Frauke

“…Neuronal damage in autoimmune neuroinflammation is the correlate for long-term disability in multiple sclerosis (MS) patients. Here, we investigated the role…”
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration by Lehmann, Sabrina M, Krüger, Christina, Park, Boyoun, Derkow, Katja, Rosenberger, Karen, Baumgart, Jan, Trimbuch, Thorsten, Eom, Gina, Hinz, Michael, Kaul, David, Habbel, Piet, Kälin, Roland, Franzoni, Eleonora, Rybak, Agnieszka, Nguyen, Duong, Veh, Rüdiger, Ninnemann, Olaf, Peters, Oliver, Nitsch, Robert, Heppner, Frank L, Golenbock, Douglas, Schott, Eckart, Ploegh, Hidde L, Wulczyn, F Gregory, Lehnardt, Seija

“…In addition to their function in gene regulation, certain microRNAs can be secreted by cells. Here, the authors show that the microRNA let-7 can cause…”
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Enhanced genome assembly and a new official gene set for Tribolium castaneum by Herndon, Nicolae, Shelton, Jennifer, Gerischer, Lizzy, Ioannidis, Panos, Ninova, Maria, Dönitz, Jürgen, Waterhouse, Robert M, Liang, Chun, Damm, Carsten, Siemanowski, Janna, Kitzmann, Peter, Ulrich, Julia, Dippel, Stefan, Oberhofer, Georg, Hu, Yonggang, Schwirz, Jonas, Schacht, Magdalena, Lehmann, Sabrina, Montino, Alice, Posnien, Nico, Gurska, Daniela, Horn, Thorsten, Seibert, Jan, Vargas Jentzsch, Iris M, Panfilio, Kristen A, Li, Jianwei, Wimmer, Ernst A, Stappert, Dominik, Roth, Siegfried, Schröder, Reinhard, Park, Yoonseong, Schoppmeier, Michael, Chung, Ho-Ryun, Klingler, Martin, Kittelmann, Sebastian, Friedrich, Markus, Chen, Rui, Altincicek, Boran, Vilcinskas, Andreas, Zdobnov, Evgeny, Griffiths-Jones, Sam, Ronshaugen, Matthew, Stanke, Mario, Brown, Sue J, Bucher, Gregor

“…The red flour beetle Tribolium castaneum has emerged as an important model organism for the study of gene function in development and physiology, for…”
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The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology by Schmitt-Engel, Christian, Schultheis, Dorothea, Schwirz, Jonas, Ströhlein, Nadi, Troelenberg, Nicole, Majumdar, Upalparna, Dao, Van Anh, Grossmann, Daniela, Richter, Tobias, Tech, Maike, Dönitz, Jürgen, Gerischer, Lizzy, Theis, Mirko, Schild, Inga, Trauner, Jochen, Koniszewski, Nikolaus D. B., Küster, Elke, Kittelmann, Sebastian, Hu, Yonggang, Lehmann, Sabrina, Siemanowski, Janna, Ulrich, Julia, Panfilio, Kristen A., Schröder, Reinhard, Morgenstern, Burkhard, Stanke, Mario, Buchhholz, Frank, Frasch, Manfred, Roth, Siegfried, Wimmer, Ernst A., Schoppmeier, Michael, Klingler, Martin, Bucher, Gregor

“…Genetic screens are powerful tools to identify the genes required for a given biological process. However, for technical reasons, comprehensive screens have…”
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Phenotypic screen and transcriptomics approach complement each other in functional genomics of defensive stink gland physiology by Lehmann, Sabrina, Atika, Bibi, Grossmann, Daniela, Schmitt-Engel, Christian, Strohlein, Nadi, Majumdar, Upalparna, Richter, Tobias, Weisskopf, Matthias, Ansari, Salim, Teuscher, Matthias, Hakeemi, Muhammad Salim, Li, Jianwei, Weissbecker, Bernhard, Klingler, Martin, Bucher, Gregor, Wimmer, Ernst A

“…Abstract Background Functional genomics uses unbiased systematic genome-wide gene disruption or analyzes natural variations such as gene expression profiles of…”
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Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia by Lehnardt, Seija, Lehmann, Sabrina, Kaul, David, Tschimmel, Katharina, Hoffmann, Olaf, Cho, Sabine, Krueger, Christina, Nitsch, Robert, Meisel, Andreas, Weber, Joerg R

“…Abstract Toll-like receptors (TLR) recognize molecular structures associated with pathogens as well as host-derived components and initiate an inflammatory…”
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Extracellularly delivered single-stranded viral RNA causes neurodegeneration dependent on TLR7 by Lehmann, Sabrina M, Rosenberger, Karen, Krüger, Christina, Habbel, Piet, Derkow, Katja, Kaul, David, Rybak, Agnieszka, Brandt, Christine, Schott, Eckart, Wulczyn, F Gregory, Lehnardt, Seija

“…Innate immune receptors represent an evolutionarily ancient system that allows organisms to detect and rapidly respond to pathogen- and host-derived factors…”
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Odoriferous Defensive stink gland transcriptome to identify novel genes necessary for quinone synthesis in the red flour beetle, Tribolium castaneum by Li, Jianwei, Lehmann, Sabrina, Weißbecker, Bernhard, Ojeda Naharros, Irene, Schütz, Stefan, Joop, Gerrit, Wimmer, Ernst A

“…Chemical defense is one of the most important traits, which endow insects the ability to conquer a most diverse set of ecological environments. Chemical…”
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Determination of 74 new psychoactive substances in serum using automated in-line solid-phase extraction-liquid chromatography-tandem mass spectrometry by Lehmann, Sabrina, Kieliba, Tobias, Beike, Justus, Thevis, Mario, Mercer-Chalmers-Bender, Katja

“…•Rapid qualitative analysis of 95 new psychoactive substances (NPS) in serum.•Fully validated method for 74 analytes.•NPS were measured by a fully automated…”
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Organ distribution of diclazepam, pyrazolam and 3-fluorophenmetrazine by Lehmann, Sabrina, Sczyslo, Alissa, Froch-Cortis, Judith, Rothschild, Markus Alexander, Thevis, Mario, Andresen-Streichert, Hilke, Mercer-Chalmers-Bender, Katja

“…•Poly-drug intoxication with designer benzodiazepines and designer stimulants.•Post-mortem redistribution of diclazepam (and its metabolites), pyrazolam and…”
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Death after misuse of anabolic substances (clenbuterol, stanozolol and metandienone) by Lehmann, Sabrina, Thomas, Andreas, Schiwy-Bochat, Karl-Heinz, Geyer, Hans, Thevis, Mario, Glenewinkel, Frank, Rothschild, Markus Alexander, Andresen-Streichert, Hilke, Juebner, Martin

“…•Quantification of stanozolol and metandienone in post-mortem femoral blood.•Detection of boldenone, clomiphene, trenbolone, clenbuterol, and…”
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On tight 6-cycle decompositions of complete 3-uniform hypergraphs by Akin, Matthew, Bunge, Ryan C., El-Zanati, Saad I., Hamilton, Joshua, Kolle, Brittany, Lehmann, Sabrina, Neiburger, Levi

“…The complete 3-uniform hypergraph of order v has a vertex set V of size v and the set of all 3-element subsets of V as its edge set. A tight 6-cycle is a…”
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Fatalities associated with NPS stimulants in the Greater Cologne area by Lehmann, Sabrina, Kieliba, Tobias, Thevis, Mario, Rothschild, Markus A., Mercer-Chalmers-Bender, Katja

“…This study centres on the prevalence of new psychoactive substances (NPS) stimulant use, and its relevance as a cause of death amongst individuals between the…”
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Post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in a case of combined drug intoxication by Gaunitz, Franziska, Lehmann, Sabrina, Thomas, Andreas, Thevis, Mario, Rothschild, Markus A., Mercer-Chalmers-Bender, Katja

“…This case report centres on the post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in the case of a 27-year-old man found…”
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Correction to: Post-mortem distribution of the synthetic cannabinoid MDMB-CHMICA and its metabolites in a case of combined drug intoxication by Gaunitz, Franziska, Lehmann, Sabrina, Thomas, Andreas, Thevis, Mario, Rothschild, Markus A., Mercer-Chalmers-Bender, Katja

“…The following clarification to the content of Table 3 (MDMB-CHMICA data from previously published cases of acute (non-fatal) and fatal drug intoxications) of…”
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Organ distribution of 4-MEC, MDPV, methoxetamine and α-PVP: comparison of QuEChERS and SPE by Lehmann, Sabrina, Schulze, Bastian, Thomas, Andreas, Kamphausen, Thomas, Thevis, Mario, Rothschild, Markus A., Mercer-Chalmers-Bender, Katja

“…Purpose An organ distribution investigation was carried out on two deceased (A and B) who consumed 4-methylethcathinone (4-MEC), methylenedioxypyrovalerone…”
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Effects of the PDE5-inhibitor vardenafil in a mouse stroke model by Royl, Georg, Balkaya, Mustafa, Lehmann, Sabrina, Lehnardt, Seija, Stohlmann, Katharina, Lindauer, Ute, Endres, Matthias, Dirnagl, Ulrich, Meisel, Andreas

“…Abstract Recent experimental studies in rodents suggest that treatment with inhibitors of phosphodiesterase type 5 (PDE5) (tadalafil, sildenafil, zaprinast)…”
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Odoriferous Defensive Stink Gland Transcriptome to Identify Novel Genes Necessary for Quinone Synthesis in the Red Flour Beetle, Tribolium castaneum: e1003596 by Li, Jianwei, Lehmann, Sabrina, Weißbecker, Bernhard, Naharros, Irene Ojeda, Schütz, Stefan, Joop, Gerrit, Wimmer, Ernst A

“…Chemical defense is one of the most important traits, which endow insects the ability to conquer a most diverse set of ecological environments. Chemical…”
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Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion by Ede, Christopher, Rudolph, Christian J., Lehmann, Sabrina, Schürer, K. Anke, Kramer, Wilfried

“…Stalling of replication forks at lesions is a serious threat to genomic integrity and cell viability. Cells have developed a variety of pathways that allow…”
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