Search Results - "Lehmann, Mirko"
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Effects of NMDA-receptor blockade by ketamine on mentalizing and its neural correlates in humans: a randomized control trial
Published in Scientific reports (11-10-2023)“…Schizophrenia is associated with various deficits in social cognition that remain relatively unaltered by antipsychotic treatment. While faulty glutamate…”
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Online monitoring of cell metabolism for studying pharmacodynamic effects
Published in Toxicology and applied pharmacology (01-04-2007)“…To characterize modes of action of substances and their cytotoxic effects Bionas GmbH has developed a new screening system to allow the continuous recording of…”
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3
Metacognitive monitoring in schizotypy: Systematic literature review and new empirical data
Published in Journal of behavior therapy and experimental psychiatry (01-12-2023)“…Deficits in metacognition, the ability to monitor one's own mental states, are key elements of the functional pathology of schizophrenia spectrum disorders…”
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Development of a multi-analyte CMOS sensor for point-of-care testing
Published in Sensing and Bio-Sensing Research (01-09-2015)“…A typical microarray experiment requires both a biochip on which the biological reactions take place and a microarray scanner for analysis and visualization of…”
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5
Unity and Diversity of Metacognition
Published in Journal of experimental psychology. General (01-10-2022)“…Despite many research efforts dedicated toward deciphering the functional architecture underlying metacognition, it is still unclear if there is a common…”
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Non-invasive measurement of cell membrane associated proton gradients by ion-sensitive field effect transistor arrays for microphysiological and bioelectronical applications
Published in Biosensors & bioelectronics (01-06-2000)“…The pH in the cellular microenvironment (pH M) is an important regulator of cell-to-cell and cell-to-host interactions. Additionally the extracellular…”
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Insights into the molecular genetic basis of individual differences in metacognition
Published in Physiology & behavior (15-05-2023)“…•We linked three genetic polymorphisms with behaviorally measured metacognition.•We found higher metacognitive bias in S/LG-allele carriers in the 5-HTTLPR…”
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8
Ketamine increases fronto-posterior functional connectivity during meta-perceptual confidence ratings
Published in Behavioural brain research (26-07-2022)“…Recent advances in the neuropsychopharmacology of metacognition indicate a constituent role of glutamate for the integrity of metamnestic processes. However,…”
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Approach to a multiparametric sensor-chip-based tumor chemosensitivity assay
Published in Anti-cancer drugs (01-01-2001)“…Although not widely practiced by oncologists, in vitro tumor chemosensitivity assays (TCA) have proved to increase the lifetime of tumor patients in…”
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Effects of ketamine on brain function during metacognition of episodic memory
Published in Neuroscience of consciousness (01-01-2021)“…Abstract Only little research has been conducted on the pharmacological underpinnings of metacognition. Here, we tested the modulatory effects of a single…”
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Polysaccharide microarrays with a CMOS based signal detection unit
Published in Biosensors & bioelectronics (15-01-2011)“…Microarray based test assays have become increasingly important tools in diagnostics for fast multi-parameter detection especially where sample volumes are…”
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12
Chip integrated fuel cell
Published in Sensors and actuators. A. Physical. (08-11-2006)“…Applications such as autonomous micro-systems for the monitoring of rooms or environmental parameters need – beside a sensor and a transmitter unit – an energy…”
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Hybrid gas sensor platform based on capacitive coupled field effect transistors: Ammonia and nitrogen dioxide detection
Published in Sensors and actuators. B, Chemical (20-10-2007)“…A versatile gas sensor platform based on capacitive coupled field effect transistors (CC-FET) was realised and successfully tested. The hybrid sensor…”
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14
New insights into the nanometer-scaled cell-surface interspace by cell-sensor measurements
Published in Experimental cell research (01-05-2005)“…The culture of adherent cells on solid surfaces is an established in vitro method, and the adhesion process of a cell is considered as an important trigger for…”
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Measurement of electrical activity of long-term mammalian neuronal networks on semiconductor neurosensor chips and comparison with conventional microelectrode arrays
Published in Biosensors & bioelectronics (15-01-2006)“…Based on complementary metal-oxide semiconductor (CMOS) technology a neurosensor chip with passive palladium electrodes was developed. The CMOS technology…”
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Simultaneous measurement of cellular respiration and acidification with a single CMOS ISFET
Published in Biosensors & bioelectronics (01-05-2001)“…In vivo, the pH value and oxygen partial pressure are the most important physico–chemical parameters in the microenvironment of human tissues. In vitro, the…”
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Thermal based flow sensor with nearly zero temperature dependence and MID-based flow channel
Published in 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS) (01-01-2017)“…For the first time, a resistance based flow sensor is presented, which shows nearly zero temperature dependence in the flow output signal without the need of…”
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Conference Proceeding -
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In vitro system for the prediction of hepatotoxic effects in primary hepatocytes
Published in ALTEX, alternatives to animal experimentation (2007)“…Prediction of liver toxicity and compound responses continues to be a major challenge for the pharmaceutical industry. In vitro studies on liver cells have…”
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An ISFET-algal ( Chlamydomonas) hybrid provides a system for eco-toxicological tests
Published in Biosensors & bioelectronics (31-05-1999)“…A cellular sensoring system was designed in which metabolism-dedicated pH-ISFETs and the unicellular green alga Chlamydomonas reinhardtii as a biological…”
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Microsensor-aided measurements of cellular signalling and metabolism on tumor cells. The cell monitoring system (cms(R))
Published in Tumor biology (1998)“…Microsensors provide instruments particularly suited for the rapid, noninvasive and on-line analysis of cell and tissue cultures. The microsensor system…”
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