Search Results - "Lehmann, Christine"

A web-based psychological support program for caregivers of children with rare chronic diseases: a randomized controlled trial by Tutus, Dunja, Niemitz, Mandy, Plener, Paul L, Fegert, Jörg M, Lehmann, Christine, Weiss, Christa, Knaevelsrud, Christine, Biehl, Lisa, Rassenhofer, Miriam

“…Approximately 50% of rare diseases have symptom onset during childhood. A high level of nursing care and an often uncertain prognosis put caregivers of the…”
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Effects of elexacaftor/tezacaftor/ivacaftor therapy on mental health of patients with cystic fibrosis by Piehler, Linus, Thalemann, Ralf, Lehmann, Christine, Thee, Stephanie, Röhmel, Jobst, Syunyaeva, Zulfiya, Stahl, Mirjam, Mall, Marcus A, Graeber, Simon Y

“…The CFTR modulator drug elexacaftor/tezacaftor/ivacaftor (ETI) was shown to improve CFTR function and clinical symptoms in patients with cystic fibrosis (CF)…”
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Plasmodium falciparum dipeptidyl aminopeptidase 3 activity is important for efficient erythrocyte invasion by the malaria parasite by Lehmann, Christine, Tan, Michele Ser Ying, de Vries, Laura E, Russo, Ilaria, Sanchez, Mateo I, Goldberg, Daniel E, Deu, Edgar

“…Parasite egress from infected erythrocytes and invasion of new red blood cells are essential processes for the exponential asexual replication of the malaria…”
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Hostile takeover by Plasmodium: reorganization of parasite and host cell membranes during liver stage egress by Graewe, Stefanie, Rankin, Kathleen E, Lehmann, Christine, Deschermeier, Christina, Hecht, Leonie, Froehlke, Ulrike, Stanway, Rebecca R, Heussler, Volker

“…The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and undergoes obligatory development within a parasitophorous vacuole in…”
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Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening by Sanchez, Mateo I, de Vries, Laura E, Lehmann, Christine, Lee, Jeong T, Ang, Kenny K, Wilson, Christopher, Chen, Steven, Arkin, Michelle R, Bogyo, Matthew, Deu, Edgar

“…Dipeptidyl aminopeptidases (DPAPs) are cysteine proteases that cleave dipeptides from the N-terminus of protein substrates and have been shown to play…”
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Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites by Hopp, Christine S, Bennett, Brandy L, Mishra, Satish, Lehmann, Christine, Hanson, Kirsten K, Lin, Jing-Wen, Rousseau, Kimberly, Carvalho, Filomena A, van der Linden, Wouter A, Santos, Nuno C, Bogyo, Matthew, Khan, Shahid M, Heussler, Volker, Sinnis, Photini

“…Proteases have been implicated in a variety of developmental processes during the malaria parasite lifecycle. In particular, invasion and egress of the…”
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A cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic development by Lehmann, Christine, Heitmann, Anna, Mishra, Satish, Burda, Paul-Christian, Singer, Mirko, Prado, Monica, Niklaus, Livia, Lacroix, Céline, Ménard, Robert, Frischknecht, Friedrich, Stanway, Rebecca, Sinnis, Photini, Heussler, Volker

“…Plasmodium parasites express a potent inhibitor of cysteine proteases (ICP) throughout their life cycle. To analyze the role of ICP in different life cycle…”
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Exoerythrocytic Plasmodium parasites secrete a cysteine protease inhibitor involved in sporozoite invasion and capable of blocking cell death of host hepatocytes by Rennenberg, Annika, Lehmann, Christine, Heitmann, Anna, Witt, Tina, Hansen, Guido, Nagarajan, Krishna, Deschermeier, Christina, Turk, Vito, Hilgenfeld, Rolf, Heussler, Volker T

“…Plasmodium parasites must control cysteine protease activity that is critical for hepatocyte invasion by sporozoites, liver stage development, host cell…”
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Development and evaluation of a patient education programme for children, adolescents, and young adults with differences of sex development (DSD) and their parents: study protocol of Empower-DSD by Wiegmann, Sabine, Ernst, Martina, Ihme, Loretta, Wechsung, Katja, Kalender, Ute, Stöckigt, Barbara, Richter-Unruh, Annette, Vögler, Sander, Hiort, Olaf, Jürgensen, Martina, Marshall, Louise, Menrath, Ingo, Schneidewind, Julia, Wagner, Isabel, Rohayem, Julia, Liesenkötter, Klaus-Peter, Wabitsch, Martin, Fuchs, Malaika, Herrmann, Gloria, Lutter, Henriette, Ernst, Gundula, Lehmann, Christine, Haase, Martina, Roll, Stephanie, Schilling, Ralph, Keil, Thomas, Neumann, Uta

“…Abstract Background Differences in sexual development (DSD) are rare diseases, which affect the chromosomal, anatomical or gonadal sex differentiation…”
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Identification and characterization of a liver stage-specific promoter region of the malaria parasite Plasmodium by Helm, Susanne, Lehmann, Christine, Nagel, Andreas, Stanway, Rebecca R, Horstmann, Sebastian, Llinas, Manuel, Heussler, Volker T

“…During the blood meal of a Plasmodium-infected mosquito, 10 to 100 parasites are inoculated into the skin and a proportion of these migrate via the bloodstream…”
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Detection of activity of telomerase in tumor cells using fiber optical biosensors by Schmidt, Peter M, Lehmann, Christine, Matthes, Eckart, Bier, Frank F

“…Human telomerase plays an important role in the cancerogenesis as it is up-regulated in 80–90% of malignant tumors. Thus, it is considered as a potential…”
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How and Why Living in Disadvantaged Communities Contributes to Neurodegeneration by Lehmann, Christine

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A New Sublingual Form of Apomorphine Appears Promising as a Rescue Therapy for Parkinsonʼs Disease by Lehmann, Christine

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Oral Fenfluramine Is Promising Therapy for Children with Dravet Syndrome by Lehmann, Christine

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Why Personality Traits in the Teen Years May Protect Against Dementia Decades Later by Lehmann, Christine

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Slow Waves of CSF During Sleep Clear Toxins Linked to Neurodegenerative Conditions by Lehmann, Christine

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Polygenic Risk Scores May Help Identify Patients at Higher Risk of Common Types of Epilepsy by Lehmann, Christine

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A Positive Test for Lyme Disease Is Not Associated with Neuropsychiatric Disorders by Lehmann, Christine

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Study Finds Increased Risk for Intracranial Subdural Hematomas in Postpartum Women with Post-Dural Puncture Headaches by Lehmann, Christine

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A Mouse Model Offers New Clues to the Underlying Mechanism at Work in Stuttering by Lehmann, Christine

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