Search Results - "Lehmann, Anders"

Intestinal SGLT1 in metabolic health and disease by Lehmann, Anders, Hornby, Pamela J

“…The Na(+)-glucose cotransporter 1 (SGLT1/SLC5A1) is predominantly expressed in the small intestine. It transports glucose and galactose across the apical…”
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Changes of clinical characteristics, distribution of red flags and prognosis in contemporary patients with wild-type transthyretin amyloidosis cardiomyopathy by Sanne Bøjet, Larsen, Bertil, Ladefoged, Anders Lehmann Dahl, Pedersen, Jens Kæstel, Skov, Tor Skibsted, Clemmensen, Steen Hvitfeldt, Poulsen

“…Increased diagnostic awareness and specific disease treatments have changed the landscape of transthyretin cardiac amyloidosis (ATTR). Patients with wild-type…”
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Prevalence and Prognostic Implications of Increased Apical-to-Basal Strain Ratio in Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement by Dahl Pedersen, Anders Lehmann, Povlsen, Jonas Agerlund, Dybro, Anne, Clemmensen, Tor Skibsted, Larsen, Anders Hostrup, Ladefoged, Bertil, Poulsen, Steen Hvitfeldt

“…The aim of this study was to investigate the preoperative prevalence, relation to symptoms, and prognostic implications of elevated left ventricular (LV)…”
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Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor by Jacobsen, Stine Engesgaard, Nørskov-Lauritsen, Lenea, Thomsen, Alex Rojas Bie, Smajilovic, Sanela, Wellendorph, Petrine, Larsson, Niklas H P, Lehmann, Anders, Bhatia, Vikram Kjøller, Bräuner-Osborne, Hans

“…The GPRC6A receptor is a recently "deorphanized" class C G protein-coupled receptor. We and others have shown that this receptor is coactivated by basic…”
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Distribution and prognostic value of left ventricular global longitudinal strain in elderly patients with symptomatic severe aortic stenosis undergoing transcatheter aortic valve replacement by Povlsen, Jonas Agerlund, Rasmussen, Vibeke Guldbrand, Vase, Henrik, Jensen, Kaare Troels, Terkelsen, Christian Juhl, Christiansen, Evald Høj, Tang, Mariann, Pedersen, Anders Lehmann Dahl, Poulsen, Steen Hvitfeldt

“…The aim of present study was to examine the preoperative prevalence and distribution of impaired left ventricular global longitudinal strain (LVGLS) in elderly…”
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Changes and Prognostic Implications of Myocardial Work in Aortic Stenosis Subtypes Undergoing Transcatheter Valve Implantation by Pedersen, Anders Lehmann Dahl, Frederiksen, Christian Alcaraz, Povlsen, Jonas Agerlund, Ladefoged, Bertil Thyrsted, Mejren, Ali Hussein Jaber, Terkelsen, Christian Juhl, Poulsen, Steen Hvitfeldt

“…Evaluation of left ventricle (LV) systolic function in patients with aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) is…”
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Incidence and predictors of worsening heart failure in patients with wild‐type transthyretin cardiac amyloidosis by Ladefoged, Bertil Thyrsted, Dybro, Anne, Dahl Pedersen, Anders Lehmann, Rasmussen, Torsten Bloch, Vase, Henrik Ølholm, Clemmensen, Tor Skibsted, Gillmore, Julian, Poulsen, Steen Hvitfeldt

“…Background Prognostic markers of survival have been identified in wild‐type transthyretin amyloidosis (ATTRwt), but limited data exist with respect to…”
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Effect of remote ischaemic conditioning on left ventricular function in ST-segment elevation myocardial infarction patients: The CONDI-2 echocardiographic sub-study by Wood, Gregory, Johnsen, Pia Hedegaard, Pedersen, Anders Lehmann Dahl, Frederiksen, Christian Alcaraz, Poulsen, Steen Hvitfeldt, Bøtker, Hans Erik, Kim, Won Yong

“…Remote ischaemic conditioning (RIC) applied to the arm by inflation and deflation of a pneumatic cuff has been shown to reduce myocardial infarct size in…”
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Clinical presentation and cardiac imaging findings in patient cases of perimyocarditis and pericarditis with a temporal association to SARS-CoV-2 vaccination by Pedersen, Anders Lehmann Dahl, Wood, Gregory, Frederiksen, Christian Alcaraz, Løgstrup, Brian Bridal, Jensen, Morten Kvistholm, Østergaard, Lars, Kim, Won Yong, Poulsen, Steen Hvitfeldt

“…Aims We aimed to investigate and present cases of perimyocarditis and pericarditis verified by cardiovascular resonance (CMR) imaging in patients with a strong…”
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Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain by Morabito, Michael V, Ravussin, Yann, Mueller, Bridget R, Skowronski, Alicja A, Watanabe, Kazuhisa, Foo, Kylie S, Lee, Samuel X, Lehmann, Anders, Hjorth, Stephan, Zeltser, Lori M, LeDuc, Charles A, Leibel, Rudolph L

“…Diet-induced obesity (DIO) resulting from consumption of a high fat diet (HFD) attenuates normal neuronal responses to leptin and may contribute to the…”
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Effects of a novel MC4R agonist on maintenance of reduced body weight in diet‐induced obese mice by Skowronski, Alicja A., Morabito, Michael V., Mueller, Bridget R., Lee, Samuel, Hjorth, Stephan, Lehmann, Anders, Watanabe, Kazuhisa, Zeltser, Lori M., Ravussin, Yann, Rosenbaum, Michael, LeDuc, Charles A., Leibel, Rudolph L.

“…Objective The physiology of the weight‐reduced (WR) state suggests that pharmacologic agents affecting energy homeostasis may have greater efficacy in WR…”
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Reducing Adverse Effects During Drug Development: The Example of Lesogaberan and Paresthesia by Rydholm, Hans, MD, PhD, von Corswant, Christian, PhD, Denison, Hans, MD, PhD, Jensen, Jörgen M., PhD, Lehmann, Anders, PhD, Ruth, Magnus, MD, PhD, Söderlind, Erik, PhD, Aurell-Holmberg, Ann, M Med Sci

“…Abstract Purpose Lesogaberan, a γ-aminobutyric acid (GABA)B receptor agonist, was developed for the treatment of gastroesophageal reflux disease in patients…”
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(R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action by Lehmann, Anders, Antonsson, Madeleine, Holmberg, Ann Aurell, Blackshaw, L Ashley, Brändén, Lena, Bräuner-Osborne, Hans, Christiansen, Bolette, Dent, John, Elebring, Thomas, Jacobson, Britt-Marie, Jensen, Jörgen, Mattsson, Jan P, Nilsson, Karolina, Oja, Simo S, Page, Amanda J, Saransaari, Pirjo, von Unge, Sverker

“…Gastroesophageal reflux disease (GERD) affects >10% of the Western population. Conventionally, GERD is treated by reducing gastric acid secretion, which is…”
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Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons by Page, Amanda J., Young, Richard L., Martin, Chris M., Umaerus, Mia, O’Donnell, Tracey A., Cooper, Nicole J., Coldwell, Jonathan R., Hulander, Malin, Mattsson, Jan P., Lehmann, Anders, Blackshaw, L. Ashley

“…Background & Aims: Inhibitory G-protein-coupled receptors have demonstrated potential in treatment of gastroesophageal reflux disease (GERD) through actions on…”
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Cannabinoid receptor agonism inhibits transient lower esophageal sphincter relaxations and reflux in dogs by Lehmann, Anders, Blackshaw, L.Ashley, Brändén, Lena, Carlsson, Anita, Jensen, Jörgen, Nygren, Emelie, Smid, Scott D.

“…Background & Aims: Transient lower esophageal sphincter relaxations (TLESRs) are the major cause of gastroesophageal acid reflux, and are triggered by…”
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4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease by Jirholt, Johan, Asling, Bengt, Hammond, Paul, Davidson, Geoffrey, Knutsson, Mikael, Walentinsson, Anna, Jensen, Jörgen M, Lehmann, Anders, Agreus, Lars, Lagerström-Fermer, Maria

“…Gastro-esophageal reflux disease (GERD) is partly caused by genetic factors. The underlying susceptibility genes are currently unknown, with the exception of…”
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Inhibition of transient LES relaxations and reflux in ferrets by GABA receptor agonists by Blackshaw, L A, Staunton, E, Lehmann, A, Dent, J

“…Transient lower esophageal sphincter (LES) relaxation is the major mechanism of gastroesophageal reflux. This study uses an established ferret model to…”
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GABAB receptors as drug targets to treat gastroesophageal reflux disease by Lehmann, Anders

“…For many years, acid-suppressive therapy has been at the forefront of treating gastroesophageal reflux disease (GERD), yet despite the advent of the proton…”
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Inhibitory effects of GABAB receptor agonists on swallowing in the dog by LEHMANN, Anders, BREMNER-DANIELSEN, Marianne, BRÄNDEN, Lena, KÄRRBERG, Lillevi

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THE EFFECT OF TRIMETAZIDINE ON INVASIVE HEMODYNAMICS AND MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION CAPACITY IN WILD-TYPE TRANSTHYRETIN CARDIOMYOPATHY by Ladefoged, Bertil, Pedersen, Anders Lehmann Dahl, Dybro, Anne, Gillmore, Julian David

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