Search Results - "Lehmann, Alexander"
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1
Proper static potential in classical lattice gauge theory at finite T
Published in The journal of high energy physics (01-07-2021)“…A bstract We compute the proper real-time interaction potential between a static quark and antiquark in classical lattice gauge theory at finite temperature…”
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2
Prediction of B cell epitopes in proteins using a novel sequence similarity-based method
Published in Scientific reports (12-08-2022)“…Prediction of B cell epitopes that can replace the antigen for antibody production and detection is of great interest for research and the biotech industry…”
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Unbiased, High-Throughput Identification of T Cell Epitopes by ELISPOT
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Recent systematic immune monitoring efforts suggest that, in humans, epitope recognition by T cells is far more complex than has been assumed based on…”
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4
Simulation strategies for the massless lattice Schwinger model in the dual formulation
Published in Nuclear physics. B (01-11-2017)“…The dual form of the massless Schwinger model on the lattice overcomes the complex action problems from two sources: a topological term, as well as non-zero…”
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Deconvoluting the T Cell Response to SARS-CoV-2: Specificity Versus Chance and Cognate Cross-Reactivity
Published in Frontiers in immunology (28-05-2021)“…SARS-CoV-2 infection takes a mild or clinically inapparent course in the majority of humans who contract this virus. After such individuals have cleared the…”
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Aleatory Epitope Recognition Prevails in Human T Cell Responses?
Published in Critical reviews in immunology (2020)“…Eli Sercarz pioneered epitope recognition by T cells. Studying mice, he made the seminal observation decades ago that epitope dominance is so unpredictable…”
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A push–pull strategy to suppress stable fly (Diptera: Muscidae) attacks on pasture cattle via a coconut oil fatty acid repellent formulation and traps with m‐cresol lures
Published in Pest management science (01-09-2023)“…BACKGROUND Stable flies [Stomoxys calcitrans (L.)] are economically important pests of cattle and other livestock. As an alternative to conventional…”
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Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance
Published in Frontiers in immunology (09-02-2021)“…CD8+ T cell immune monitoring aims at measuring the size and functions of antigen-specific CD8+ T cell populations, thereby providing insights into…”
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Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping
Published in Frontiers in immunology (26-04-2019)“…T cell immunity is traditionally assessed through functional recall assays, which detect the consequences of the T cells' antigen encounter, or via…”
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CERI, CEFX, and CPI: Largely Improved Positive Controls for Testing Antigen-Specific T Cell Function in PBMC Compared to CEF
Published in Cells (Basel, Switzerland) (27-01-2021)“…Monitoring antigen-specific T cell immunity relies on functional tests that require T cells and antigen presenting cells to be uncompromised. Drawing of blood,…”
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Functional T Cell Reactivity to Melanocyte Antigens Is Lost during the Progression of Malignant Melanoma, but Is Restored by Immunization
Published in Cancers (09-01-2021)“…Healthy human subjects develop spontaneous CD8+ T cell responses to melanoma associated antigens (MA) expressed by normal melanocytes, such as Tyrosinase,…”
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How Reliable Are Predictions of CD8+ T Cell Epitope Recognition? Lessons for Cancer
Published in Onco (17-04-2024)“…Synthetic peptides derived from antigen sequences are essential reagents for the detection of CD8+ cytotoxic T lymphocytes (CTLs), in assays such as…”
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Spatio-Temporal Characteristics of Inhibition Mapped by Optical Stimulation in Mouse Olfactory Bulb
Published in Frontiers in neural circuits (22-03-2016)“…Mitral and tufted cells (MTCs) of the mammalian olfactory bulb are connected via dendrodendritic synapses with inhibitory interneurons in the external…”
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High-Throughput GLP-Capable Target Cell Visualization Assay for Measuring Cell-Mediated Cytotoxicity
Published in Cells (Basel, Switzerland) (24-04-2018)“…One of the primary effector functions of immune cells is the killing of virus-infected or malignant cells in the body. Natural killer (NK) and CD8 effector T…”
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The (tremendous) gap between predicted epitopes and those actually recognized by CD8 T cells
Published in The Journal of immunology (1950) (01-05-2020)“…In order to monitor CD8 cell immunity it is essential to know the peptide determinant(s) of the antigen that these T cells recognize. Relevant peptide…”
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Critical Reviews in Immunology
Published in Critical reviews in immunology (2020)“…Eli Sercarz pioneered epitope recognition by T cells. Studying mice, he made the seminal observation decades ago that epitope dominance is so unpredictable…”
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The brain robot "Herr Tie": discovering basic principles of brain function at primary school
Published in Advances in physiology education (01-09-2016)Get full text
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18
Effect of multi-condition training and speech enhancement methods on spoofing detection
Published in 2016 First International Workshop on Sensing, Processing and Learning for Intelligent Machines (SPLINE) (01-07-2016)“…Many researchers have demonstrated the good performance of spoofing detection systems under clean training and testing conditions. However, it is well known…”
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Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents
Published in The Journal of neuroscience (23-01-2008)“…Abnormal accumulation of soluble oligomers of amyloid beta (Abeta) is believed to cause malfunctioning of neurons in Alzheimer's disease. It has been shown…”
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Amyloid β Oligomers (Aβ 1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents
Published in The Journal of neuroscience (23-01-2008)“…Abnormal accumulation of soluble oligomers of amyloid β (Aβ) is believed to cause malfunctioning of neurons in Alzheimer's disease. It has been shown that Aβ…”
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