Search Results - "Lehmann, Alexander"

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  1. 1

    Proper static potential in classical lattice gauge theory at finite T by Lehmann, Alexander, Rothkopf, Alexander

    Published in The journal of high energy physics (01-07-2021)
    “…A bstract We compute the proper real-time interaction potential between a static quark and antiquark in classical lattice gauge theory at finite temperature…”
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    Journal Article
  2. 2

    Prediction of B cell epitopes in proteins using a novel sequence similarity-based method by Ras-Carmona, Alvaro, Lehmann, Alexander A., Lehmann, Paul V., Reche, Pedro A.

    Published in Scientific reports (12-08-2022)
    “…Prediction of B cell epitopes that can replace the antigen for antibody production and detection is of great interest for research and the biotech industry…”
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    Journal Article
  3. 3

    Unbiased, High-Throughput Identification of T Cell Epitopes by ELISPOT by Lehmann, Paul V, Roen, Diana R, Lehmann, Alexander A

    “…Recent systematic immune monitoring efforts suggest that, in humans, epitope recognition by T cells is far more complex than has been assumed based on…”
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    Journal Article
  4. 4

    Simulation strategies for the massless lattice Schwinger model in the dual formulation by Göschl, Daniel, Gattringer, Christof, Lehmann, Alexander, Weis, Christoph

    Published in Nuclear physics. B (01-11-2017)
    “…The dual form of the massless Schwinger model on the lattice overcomes the complex action problems from two sources: a topological term, as well as non-zero…”
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    Journal Article
  5. 5

    Deconvoluting the T Cell Response to SARS-CoV-2: Specificity Versus Chance and Cognate Cross-Reactivity by Lehmann, Alexander A., Kirchenbaum, Greg A., Zhang, Ting, Reche, Pedro A., Lehmann, Paul V.

    Published in Frontiers in immunology (28-05-2021)
    “…SARS-CoV-2 infection takes a mild or clinically inapparent course in the majority of humans who contract this virus. After such individuals have cleared the…”
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    Journal Article
  6. 6

    Aleatory Epitope Recognition Prevails in Human T Cell Responses? by Lehmann, Paul V, Lehmann, Alexander A

    Published in Critical reviews in immunology (2020)
    “…Eli Sercarz pioneered epitope recognition by T cells. Studying mice, he made the seminal observation decades ago that epitope dominance is so unpredictable…”
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    Journal Article
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    Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance by Lehmann, Alexander A, Zhang, Ting, Reche, Pedro A, Lehmann, Paul V

    Published in Frontiers in immunology (09-02-2021)
    “…CD8+ T cell immune monitoring aims at measuring the size and functions of antigen-specific CD8+ T cell populations, thereby providing insights into…”
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    Journal Article
  9. 9

    Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping by Lehmann, Paul V, Suwansaard, Maneewan, Zhang, Ting, Roen, Diana R, Kirchenbaum, Greg A, Karulin, Alexey Y, Lehmann, Alexander, Reche, Pedro A

    Published in Frontiers in immunology (26-04-2019)
    “…T cell immunity is traditionally assessed through functional recall assays, which detect the consequences of the T cells' antigen encounter, or via…”
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    Journal Article
  10. 10

    CERI, CEFX, and CPI: Largely Improved Positive Controls for Testing Antigen-Specific T Cell Function in PBMC Compared to CEF by Lehmann, Alexander A, Reche, Pedro A, Zhang, Ting, Suwansaard, Maneewan, Lehmann, Paul V

    Published in Cells (Basel, Switzerland) (27-01-2021)
    “…Monitoring antigen-specific T cell immunity relies on functional tests that require T cells and antigen presenting cells to be uncompromised. Drawing of blood,…”
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    Journal Article
  11. 11

    Functional T Cell Reactivity to Melanocyte Antigens Is Lost during the Progression of Malignant Melanoma, but Is Restored by Immunization by Przybyla, Anna, Lehmann, Alexander A, Zhang, Ting, Mackiewicz, Jacek, Galus, Łukasz, Kirchenbaum, Greg A, Mackiewicz, Andrzej, Lehmann, Paul V

    Published in Cancers (09-01-2021)
    “…Healthy human subjects develop spontaneous CD8+ T cell responses to melanoma associated antigens (MA) expressed by normal melanocytes, such as Tyrosinase,…”
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    Journal Article
  12. 12

    How Reliable Are Predictions of CD8+ T Cell Epitope Recognition? Lessons for Cancer by Lehmann, Alexander A., Lehmann, Paul V., Todryk, Stephen

    Published in Onco (17-04-2024)
    “…Synthetic peptides derived from antigen sequences are essential reagents for the detection of CD8+ cytotoxic T lymphocytes (CTLs), in assays such as…”
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    Journal Article
  13. 13

    Spatio-Temporal Characteristics of Inhibition Mapped by Optical Stimulation in Mouse Olfactory Bulb by Lehmann, Alexander, D'Errico, Anna, Vogel, Martin, Spors, Hartwig

    Published in Frontiers in neural circuits (22-03-2016)
    “…Mitral and tufted cells (MTCs) of the mammalian olfactory bulb are connected via dendrodendritic synapses with inhibitory interneurons in the external…”
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    Journal Article
  14. 14

    High-Throughput GLP-Capable Target Cell Visualization Assay for Measuring Cell-Mediated Cytotoxicity by Welter, Anna, Sundararaman, Srividya, Li, Ruliang, Zhang, Ting, Karulin, Alexey Y, Lehmann, Alexander, Naeem, Villian, Roen, Diana R, Kuerten, Stefanie, Lehmann, Paul V

    Published in Cells (Basel, Switzerland) (24-04-2018)
    “…One of the primary effector functions of immune cells is the killing of virus-infected or malignant cells in the body. Natural killer (NK) and CD8 effector T…”
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    Journal Article
  15. 15

    The (tremendous) gap between predicted epitopes and those actually recognized by CD8 T cells by Kirchenbaum, Greg A, Lehmann, Alexander, Lehmann, Paul V

    Published in The Journal of immunology (1950) (01-05-2020)
    “…In order to monitor CD8 cell immunity it is essential to know the peptide determinant(s) of the antigen that these T cells recognize. Relevant peptide…”
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    Journal Article
  16. 16

    Critical Reviews in Immunology by Lehmann, Paul V, Lehmann, Alexander A

    Published in Critical reviews in immunology (2020)
    “…Eli Sercarz pioneered epitope recognition by T cells. Studying mice, he made the seminal observation decades ago that epitope dominance is so unpredictable…”
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    Journal Article
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    Effect of multi-condition training and speech enhancement methods on spoofing detection by Hong Yu, Sarkar, Achintya, Thomsen, Dennis Alexander Lehmann, Zheng-Hua Tan, Zhanyu Ma, Jun Guo

    “…Many researchers have demonstrated the good performance of spoofing detection systems under clean training and testing conditions. However, it is well known…”
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    Conference Proceeding
  19. 19

    Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents by Nimmrich, Volker, Grimm, Christiane, Draguhn, Andreas, Barghorn, Stefan, Lehmann, Alexander, Schoemaker, Hans, Hillen, Heinz, Gross, Gerhard, Ebert, Ulrich, Bruehl, Claus

    Published in The Journal of neuroscience (23-01-2008)
    “…Abnormal accumulation of soluble oligomers of amyloid beta (Abeta) is believed to cause malfunctioning of neurons in Alzheimer's disease. It has been shown…”
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    Journal Article
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    Amyloid β Oligomers (Aβ 1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents by Nimmrich, Volker, Grimm, Christiane, Draguhn, Andreas, Barghorn, Stefan, Lehmann, Alexander, Schoemaker, Hans, Hillen, Heinz, Gross, Gerhard, Ebert, Ulrich, Bruehl, Claus

    Published in The Journal of neuroscience (23-01-2008)
    “…Abnormal accumulation of soluble oligomers of amyloid β (Aβ) is believed to cause malfunctioning of neurons in Alzheimer's disease. It has been shown that Aβ…”
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    Journal Article